Dissecting Abdominal Aortic Aneurysm Is Aggravated by Genetic Inactivation of LIGHT (TNFSF14)

Autor: Andrea Herrero-Cervera, Carla Espinós-Estévez, Susana Martín-Vañó, Alida Taberner-Cortés, María Aguilar-Ballester, Ángela Vinué, Laura Piqueras, Sergio Martínez-Hervás, Herminia González-Navarro

Publikováno v: Biomedicines, Vol 9, Iss 11, p 1518 (2021)

Abdominal aortic aneurysm (AAA), is a complex disorder characterized by vascular vessel wall remodeling. LIGHT (TNFSF14) is a proinflammatory cytokine associated with vascular disease. In the present study, the impact of genetic inactivation of Light

Externí odkaz: https://doaj.org/article/f74087f9be3e4f8498c9c7cce0dd4d90

Srebf2 Locus Overexpression Reduces Body Weight, Total Cholesterol and Glucose Levels in Mice Fed with Two Different Diets

Autor: Irene Andrés-Blasco, Sebastian Blesa, Ángela Vinué, Herminia González-Navarro, José Tomás Real, Sergio Martínez-Hervás, Julián Carretero, Antonio Ferrández-Izquierdo, Felipe Javier Chaves, Ana-Bárbara García-García

Publikováno v: Nutrients, Vol 12, Iss 10, p 3130 (2020)

Macronutrients represent risk factors for hyperlipidemia or diabetes. Lipid alterations and type 2 diabetes mellitus are global health problems. Overexpression of sterol regulatory element-binding factor (Srebf2) in transgenic animals is linked to el

Externí odkaz: https://doaj.org/article/7d82cac72d1d4f90a10e39de404c32b3

Understanding the Impact of Dietary Cholesterol on Chronic Metabolic Diseases through Studies in Rodent Models

Autor: Ángela Vinué, Andrea Herrero-Cervera, Herminia González-Navarro

Publikováno v: Nutrients, Vol 10, Iss 7, p 939 (2018)

The development of certain chronic metabolic diseases has been attributed to elevated levels of dietary cholesterol. However, decades of research in animal models and humans have demonstrated a high complexity with respect to the impact of dietary ch

Externí odkaz: https://doaj.org/article/881040d9937044068c75e74175a45551

Type 1 diabetic mellitus patients with increased atherosclerosis risk display decreased CDKN2A/2B/2BAS gene expression in leukocytes

Autor: Herminia González-Navarro, Juan F. Ascaso, Verónica Sánchez-García, Andrea Herrero-Cervera, Ángela Vinué, Sergio Martínez-Hervás, Deborah J. Burks, José T. Real

Publikováno v: Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-12 (2019)
Martínez Hervás, Sergio Sánchez-García, Verónica Herrero-Cervera, Andrea Vinué Visús, María Ángela Real Collado, José Tomás Ascaso Gimilio, Juan Francisco Burks, Deborah Jane González Navarro, Herminia 2019 Type 1 diabetic mellitus patientswith increased atherosclerosisriskdisplay decreased CDKN2A/2B/2BAS gene expression in leukocytes Journal Of Translational Medicine 17 1 222
Journal of Translational Medicine
RODERIC. Repositorio Institucional de la Universitat de Valéncia
instname

Background Type 1 diabetes mellitus (T1DM) patients display increased risk of cardiovascular disease (CVD) and are characterized by a diminished regulatory T (Treg) cell content or function. Previous studies have shown an association between decrease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f8d1c14c7b49302adbadd1e70fe7b9
http://link.springer.com/article/10.1186/s12967-019-1977-1

Dapagliflozin Does Not Modulate Atherosclerosis in Mice with Insulin Resistance

Autor: Herminia González-Navarro, Ángela Vinué, María Aguilar-Ballester, José T. Real, Andrea Herrero-Cervera, Deborah J. Burks, Alida Taberner-Cortés, Sergio Martínez-Hervás

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 9216, p 9216 (2020)
Volume 21
Issue 23

Type 2 diabetes mellitus (T2DM) increases morbimortality in humans via enhanced susceptibility to cardiovascular disease (CVD). Sodium-glucose co-transporter 2 inhibitors (SGLT2i) are drugs designed for T2DM treatment to diminish hyperglycaemia by re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd37611ad32f336ede99cadde2d9655
https://pubmed.ncbi.nlm.nih.gov/33287201