Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ángela, Bella"'
Autor:
Claudia Augusta Di Trani, Assunta Cirella, Leire Arrizabalaga, Maite Alvarez, Ángela Bella, Myriam Fernandez-Sendin, Joan Salvador Russo-Cabrera, Celia Gomar, Nuria Ardaiz, Alvaro Teijeira, Elixabet Bolaños, José González-Gomariz, Itziar Otano, Fernando Aranda, Belén Palencia, Aina Segués, Shuyu Huang, Sander M.J. van Duijnhoven, Andrea van Elsas, Ignacio Melero, Pedro Berraondo
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 599-616 (2023)
IL-12 is a potent cytokine for cancer immunotherapy. However, its systemic delivery as a recombinant protein has shown unacceptable toxicity in the clinic. Currently, the intratumoral injection of IL-12-encoding mRNA or DNA to avoid such side effects
Externí odkaz:
https://doaj.org/article/b7ab44ddf91c4d09a6a701937d803612
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTOur recent research has unveiled the potential of locoregional immunotherapy. Cytokine-armored viral vectors, such as modified vaccinia virus Ankara vector encoding single-chain interleukin-12 (MVA.scIL-12), can target the omentum and elicit
Externí odkaz:
https://doaj.org/article/61006135d7684fc8aaa8a533103f3eec
Autor:
Claudia Augusta Di Trani, Assunta Cirella, Leire Arrizabalaga, Ángela Bella, Myriam Fernandez-Sendin, Joan Salvador Russo-Cabrera, Celia Gomar, Irene Olivera, Elizabeth Bolaños, José González-Gomariz, Maite Álvarez, Iñaki Etxeberria, Belen Palencia, Álvaro Teijeira, Ignacio Melero, Pedro Berraondo, Fernando Aranda
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTPrevious studies have shown that local delivery of tumor antigen-specific CD8+ T lymphocytes engineered to transiently express single-chain IL-12 mRNA is highly efficacious. Peritoneal dissemination of cancer is a frequent and often fatal pat
Externí odkaz:
https://doaj.org/article/7995ddacfe9f449ca1ff8dccf0f9a256
Autor:
Ángela Bella, Leire Arrizabalaga, Claudia Augusta Di Trani, Assunta Cirella, Myriam Fernandez-Sendin, Celia Gomar, Joan Salvador Russo-Cabrera, Inmaculada Rodríguez, José González-Gomariz, Maite Alvarez, Álvaro Teijeira, José Medina-Echeverz, Maria Hinterberger, Hubertus Hochrein, Ignacio Melero, Pedro Berraondo, Fernando Aranda
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Recombinant-modified vaccinia virus Ankara (rMVA) is known to elicit potent antitumor immune responses in preclinical models due to its inherent ability to activate the innate immune system and the activation of adaptive responses mediated by the exp
Externí odkaz:
https://doaj.org/article/f9d020b0324c489cb77988b46440b9e8
Autor:
Claudia Augusta Di Trani, Assunta Cirella, Leire Arrizabalaga, Ángela Bella, Myriam Fernandez-Sendin, Joan Salvador Russo-Cabrera, Celia Gomar, Irene Olivera, Elizabeth Bolaños, José González-Gomariz, Maite Álvarez, Iñaki Etxeberria, Belen Palencia, Álvaro Teijeira, Ignacio Melero, Pedro Berraondo, Fernando Aranda
Publikováno v:
OncoImmunology. 12
Publikováno v:
Clinical Cancer Research. 28:1993-1995
Ovarian cancer is often limited to the peritoneal cavity in the form of peritoneal carcinomatosis. Peritoneal spreading offers the opportunity for locoregional delivery of combinations of immunotherapy agents, maximizing bioavailability while potenti
Autor:
Ángela, Bella, Leire, Arrizabalaga, Claudia Augusta, Di Trani, Myriam, Fernández-Sendin, Alvaro, Teijeira, Joan Salvador, Russo-Cabrera, Ignacio, Melero, Pedro, Berraondo, Fernando, Aranda
Publikováno v:
International review of cell and molecular biology. 371
Ovarian cancer often spreads out of the ovary before a patient is diagnosed and is the deadliest gynecological malignancy. The aggressiveness of ovarian cancer is determined by the progression in the form of peritoneal carcinomatosis, a stage with a
Autor:
Ángela Bella, Leire Arrizabalaga, Claudia Augusta Di Trani, Myriam Fernández-Sendin, Alvaro Teijeira, Joan Salvador Russo-Cabrera, Ignacio Melero, Pedro Berraondo, Fernando Aranda
Publikováno v:
International Review of Cell and Molecular Biology ISBN: 9780323994002
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::418d85ffd5d707f6df1f4dfdfa767e03
https://doi.org/10.1016/bs.ircmb.2022.04.017
https://doi.org/10.1016/bs.ircmb.2022.04.017