Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ángel M, Carrión"'
Autor:
Mercedes M. Pérez-Jiménez, José M. Monje-Moreno, Ana María Brokate-Llanos, Mónica Venegas-Calerón, Alicia Sánchez-García, Paula Sansigre, Amador Valladares, Sara Esteban-García, Irene Suárez-Pereira, Javier Vitorica, José Julián Ríos, Marta Artal-Sanz, Ángel M. Carrión, Manuel J. Muñoz
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Sul-2 is a steroid sulfatase in c.elegans. Here the authors show that, in the absence of sul-2 enzymatic activity, worm lifespan is increased, and that chemical inhibition ameliorates symptoms of neurodegenerative disorders in worms and mice.
Externí odkaz:
https://doaj.org/article/873769f1ad43491084d967f67bef724d
Autor:
Enrique Navas-Pérez, Cristina Vicente-García, Serena Mirra, Demian Burguera, Noèlia Fernàndez-Castillo, José Luis Ferrán, Macarena López-Mayorga, Marta Alaiz-Noya, Irene Suárez-Pereira, Ester Antón-Galindo, Fausto Ulloa, Carlos Herrera-Úbeda, Pol Cuscó, Rafael Falcón-Moya, Antonio Rodríguez-Moreno, Salvatore D’Aniello, Bru Cormand, Gemma Marfany, Eduardo Soriano, Ángel M. Carrión, Jaime J. Carvajal, Jordi Garcia-Fernàndez
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-27 (2020)
Abstract Background One of the most unusual sources of phylogenetically restricted genes is the molecular domestication of transposable elements into a host genome as functional genes. Although these kinds of events are sometimes at the core of key m
Externí odkaz:
https://doaj.org/article/fedd01eb02c446829d850715c9b40a40
Autor:
Monica, Cubillos-Rojas, Taiane, Schneider, Ouadah, Hadjebi, Leonardo, Pedrazza, Jarbas Rodrigues, de Oliveira, Francina, Langa, Jean-Louis, Guénet, Joan, Duran, Josep Maria, de Anta, Soledad, Alcántara, Rocio, Ruiz, Eva María, Pérez-Villegas, Francisco J, Aguilar-Montilla, Ángel M, Carrión, Jose Angel, Armengol, Emma, Baple, Andrew H, Crosby, Ramon, Bartrons, Francesc, Ventura, Jose Luis, Rosa
Publikováno v:
Oncotarget
A mutation in the HERC2 gene has been linked to a severe neurodevelopmental disorder with similarities to the Angelman syndrome. This gene codifies a protein with ubiquitin ligase activity that regulates the activity of tumor protein p53 and is invol