Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Ángel G, Valdivieso"'
1
Akademický článek
N-acetyl cysteine reverts the proinflammatory state induced by cigarette smoke extract in lung Calu-3 cells
Autor: Ángel G. Valdivieso, Andrea V. Dugour, Verónica Sotomayor, Mariángeles Clauzure, Juan M. Figueroa, Tomás A. Santa-Coloma
Publikováno v: Redox Biology, Vol 16, Iss , Pp 294-302 (2018)
Chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF) are lethal pulmonary diseases. Cigarette consumption is the main cause for development of COPD, while CF is produced by mutations in the CFTR gene. Although these diseases have a d
Externí odkaz: https://doaj.org/article/1e269b3b2d90436888cf218fe1e25ecf
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2
Akademický článek
The Chloride Anion Acts as a Second Messenger in Mammalian Cells - Modifying the Expression of Specific Genes
Autor: Ángel G. Valdivieso, Mariángeles Clauzure, Macarena Massip-Copiz, Tomás A. Santa-Coloma
Publikováno v: Cellular Physiology and Biochemistry, Vol 38, Iss 1, Pp 49-64 (2016)
Background/Aims: Cystic Fibrosis (CF) is caused by mutations in the CFTR gene, encoding a cAMP-activated chloride (Cl-) channel. We have previously demonstrated that the expression of several genes can be modulated by the CFTR activity; among them, S
Externí odkaz: https://doaj.org/article/719819a69df041a19ef8bf3808521a39
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3
Apolipoprotein E4 heterologous expression, purification under non-denaturing conditions, and effects on neuronal clonal cell lines
Autor: Ezequiel Serrano, Francisco J. Barrantes, Ángel G. Valdivieso
Publikováno v: Protein Expression and Purification. 2023, 210
The ε4 allele of the apolipoprotein E gene (APOE4) constitutes the main genetic risk factor for late-onset Alzheimer disease (AD). High amounts of pure apolipoprotein E4 (ApoE4), in a rapid and reproducible fashion, could be of value for studying it
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb4e71b8f678ca0f55dcd5936e175b60
https://doi.org/10.1016/j.pep.2023.106312
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4
The chloride anion as a signalling effector
Autor: Ángel G. Valdivieso, Tomás A. Santa-Coloma
Publikováno v: Biological Reviews. 2019, 94(5)
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
Fil: Valdivieso, Ángel Gabriel. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas. Laboratorio de Biología Celular y Molecular; Argentina Fil: Valdivieso, Ángel Gabriel. Consejo Nac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1acd0fe5c9d44377dcd48a72bf43997c
https://doi.org/10.1111/brv.12536
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5
NLR family pyrin domain containing 3 (NLRP3) and caspase 1 (CASP1) modulation by intracellular Cl
Autor: Mariángeles, Clauzure, Ángel G, Valdivieso, Andrea V, Dugour, Consuelo, Mori, María M, Massip-Copiz, María Á, Aguilar, Verónica, Sotomayor, Cristian J A, Asensio, Juan M, Figueroa, Tomás A, Santa-Coloma
Publikováno v: Immunology
The impairment of the cystic fibrosis transmembrane conductance regulator (CFTR) activity induces intracellular chloride (Cl(–)) accumulation. The anion Cl(–), acting as a second messenger, stimulates the secretion of interleukin‐1β (IL‐1β)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::afe30d4e712b4a464e6ddc05e5cea28e
https://pubmed.ncbi.nlm.nih.gov/33835494
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6
Epidermal growth factor receptor activity upregulates lactate dehydrogenase A expression, lactate dehydrogenase activity, and lactate secretion in cultured IB3-1 cystic fibrosis lung epithelial cells
Autor: María Macarena Massip-Copiz, Mariángeles Clauzure, Ángel G. Valdivieso, María Ángeles Aguilar, Consuelo Mori, Tomás A. Santa-Coloma, Cristian J A Asensio
Publikováno v: Postprint de artículo publicado en Biochemistry and Cell Biology. 2021, 99 (4)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
Cystic fibrosis (CF) is caused by mutations in the CFTR gene. It has been postulated that a reduced HCO3 − transport in CF through CFTR may lead to a decreased airway surface liquid (ASL) pH. In contrast, others have reported no changes in the extr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3452890939cbdbdba8d607be4bbd0038
https://pubmed.ncbi.nlm.nih.gov/33481676
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7
NLR family pyrin domain containing 3 (NLRP3) and caspase 1 (CASP1) modulation by intracellular Cl– concentration
Autor: María M. Massip-Copiz, Consuelo Mori, Verónica Sotomayor, Ángel G. Valdivieso, Mariángeles Clauzure, Andrea V. Dugour, María Á. Aguilar, Juan Manuel Figueroa, Tomás A. Santa-Coloma, Cristian J. A. Asensio
Publikováno v: Immunology Vol.163, No.4, 2021
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
Fil: Clauzure, Mariángeles. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas. Laboratorio de Biología Celular y Molecular; Argentina Fil: Clauzure, Mariángeles. Consejo Nacional de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df0f94cac0d0faeaf5fefa17b1be5f18
https://repositorio.uca.edu.ar/handle/123456789/14599
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8
CFTR chloride channel activity modulates the mitochondrial morphology in cultured epithelial cells
Autor: Camila Falduti, Tomás A. Santa-Coloma, Ángel G. Valdivieso, Rocío García, Raquel Jara, Mariángeles Clauzure, María M. Massip-Copiz, María Á. Aguilar
Publikováno v: International Journal of Biochemistry and Cell Biology, Vol. 135, 105976, 2021
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
Fil: García Solcá, Rocío. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas. Laboratorio de Biología Celular y Molecular; Argentina Fil: García Solcá, Rocío. Consejo Nacional de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a00f741d84236988b83d64235b74cf1f
https://repositorio.uca.edu.ar/handle/123456789/14597
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9
Identification and characterization of human PEIG-1/GPRC5A as a 12-Otetradecanoyl phorbol-13-acetate (TPA) and PKC-induced gene
Autor: Tomás A. Santa Coloma, María Á. Aguilar, Ángel G. Valdivieso, Consuelo Mori, María M. Massip-Copiz, Eduardo G. Cafferata, Mariángeles Clauzure
Publikováno v: Archives of Biochemistry and Biophysics Vol. 687,108375, 2020
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
Fil: Mori, Consuelo. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas. Laboratorio de Biología Celular y Molecular; Argentina Fil: Mori, Consuelo. Consejo Nacional de Investigaciones
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020b85b4e65d08e01f6e4cf559479d3d
https://repositorio.uca.edu.ar/handle/123456789/14592
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10
Intracellular Chloride Concentration Changes Modulate IL-1β Expression and Secretion in Human Bronchial Epithelial Cultured Cells
Autor: Tomás A. Santa-Coloma, Ángel G. Valdivieso, Consuelo Mori, Mariángeles Clauzure, Juan Manuel Figueroa, María M. Massip-Copiz, Andrea V. Dugour
Publikováno v: Journal of Cellular Biochemistry. 118:2131-2140
Cystic fibrosis (CF) is caused by mutations in the CFTR gene, which encodes a cAMP-regulated chloride channel. Several cellular functions are altered in CF cells. However, it is not clear how the CFTR failure induces those alterations. We have found
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c773284f6b8fe348a3a6b4eda4039a24
https://doi.org/10.1002/jcb.25850
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