Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Álvaro Fernando da Silva do Nascimento"'
Autor:
Tassiane Assíria Fontes Martins, Lívia de Figueiredo Diniz, Ana Lia Mazzeti, Álvaro Fernando da Silva do Nascimento, Sérgio Caldas, Ivo Santana Caldas, Isabel Mayer de Andrade, Isabela Ribeiro, Maria Terezinha Bahia
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128707 (2015)
The nitroheterocyclic drugs nifurtimox and benznidazole are first-line drugs available to treat Chagas disease; however, they have limitations, including long treatment courses and toxicity. Strategies to overcome these limitations include the identi
Externí odkaz:
https://doaj.org/article/a55bc8ce1c974b32bf57041861773590
Autor:
Maria Terezinha Bahia, Isabel Mayer de Andrade, Tassiane Assíria Fontes Martins, Álvaro Fernando da Silva do Nascimento, Lívia de Figueiredo Diniz, Ivo Santana Caldas, André Talvani, Bernadette Bourdin Trunz, Els Torreele, Isabela Ribeiro
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 11, p e1870 (2012)
BACKGROUND: New safe and effective treatments for Chagas disease (CD) are urgently needed. Current chemotherapy options for CD have significant limitations, including failure to uniformly achieve parasitological cure or prevent the chronic phase of C
Externí odkaz:
https://doaj.org/article/c4e69245bf3842dc952c48b2f38e205f
Autor:
Lucas Eduardo Lessa Mussi, Bruno Victor De Souza Lima, Gabriel Côrrea Costa, Ian Lucas Leite Veloso, Sollon Nathan Freitas Almeida, Geraldo César Barroso De Souza, Álvaro Fernando Da Silva Do Nascimento
Publikováno v:
Saúde Integrativa: a saúde nos conecta! ISBN: 9786586700886
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0564373aec76fdb1ccefcf2c41aa18b8
https://doi.org/10.29327/547549.1-16
https://doi.org/10.29327/547549.1-16
Autor:
Álvaro Fernando da Silva do Nascimento, Maria Terezinha Bahia, Pollyanna Álvaro Spósito, Karolina R. Gonçalves, Isabela Ribeiro, Lívia de Figueiredo Diniz, Vanessa Carla Furtado Mosqueira, Ana Lia Mazzeti, George Luiz Lins Machado-Coelho
Publikováno v:
Biochemical Pharmacology. 148:213-221
Benznidazole and nifurtimox-treatments regimens currently used in human are supported by very limited experimental data. This study was designed to evaluate the time and dose dependence for efficacy of the most important nitroheterocyclic drugs in us
Autor:
Wanderson Geraldo de Lima, Paulo Marcos da Matta Guedes, Ivo Santana Caldas, Lúcia Maria da Cunha Galvão, Lívia de Figueiredo Diniz, Sérgio Caldas, Álvaro Fernando da Silva do Nascimento, Maria Terezinha Bahia
Publikováno v:
Repositório Institucional da UFOP
Universidade Federal de Ouro Preto (UFOP)
instacron:UFOP
Universidade Federal de Ouro Preto (UFOP)
instacron:UFOP
This study was designed to verify the relationship between IgG antibodies isotypes and myocarditis in Trypanosoma cruzi infection using mice and dogs infected with different T. cruzi strains. The animals were infected with benznidazole-susceptible Be
Autor:
Ivo Santana Caldas, Karolina R. Gonçalves, Luiz F. Marques, David M. Shackleford, Ana Lia Mazzeti, Eric Chatelain, Álvaro Fernando da Silva do Nascimento, Ludmilla Walter Reis Mota, Lívia de Figueiredo Diniz, Karen L. White, Maria Koltun, Jessica Saunders, Ivan Scandale, Susan A. Charman, André Talvani, Maria Terezinha Bahia
Publikováno v:
Antimicrobial Agents and Chemotherapy. 58:4362-4370
This study was designed to verify the in vivo efficacy of sulfoxide and sulfone fexinidazole metabolites following oral administration in a murine model of Chagas disease. Female Swiss mice infected with the Y strain of Trypanosoma cruzi were treated
Autor:
Álvaro Fernando da Silva do Nascimento, Raimundo Marques do Nascimento Neto, Maria Terezinha Bahia, André Talvani, Tassiane Assíria Fontes Martins, Paulo Marcos da Matta Guedes, Maira Araújo Azevedo, Ivo Santana Caldas, Fabiane Matos dos Santos, Wanderson Geraldo de Lima, Lívia de Figueiredo Diniz, Rosália Morais Torres
Publikováno v:
Tropical Medicine & International Health. 18:75-84
Objectives The cardiac form of Chagas disease is evidenced by a progressive cardiac inflammation that leads to myocarditis, fibrosis and electrocardiographic (ECG) conduction abnormalities. Considering these characteristics, the aim of this study was
Autor:
Ivo Santana Caldas, Maira Araújo Azevedo, Maria Terezinha Bahia, Karolina R. Gonçalves, Lívia de Figueiredo Diniz, Rosália Moraes Torres, Lilian Melo, Vivian Paulino Figueiredo, Wanderson Geraldo de Lima, André Talvani, Álvaro Fernando da Silva do Nascimento
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 84:325-331
Chagas cardiomyopathy remodeling is based on the presence of Trypanosoma cruzi in heart tissue and on the complex inflammatory response leading to a myocardium fibrosis and alterations in conductive and functional heart parameters. This study aims to
Autor:
M. T. Bahia, Maria Adelaide Do-Valle-Matta, Ivo Santana Caldas, Janeusa Trindade de Souto, Manuela Sales Lima Nascimento, Paulo Marcos da Matta Guedes, Álvaro Fernando da Silva do Nascimento, Antônia Cláudia Jácome da Câmara, T.D.R. Albuquerque, Lúcia Maria da Cunha Galvão, André Talvani
Publikováno v:
Journal of comparative pathology. 153(4)
Dogs are the primary urban reservoir of Leishmania infantum and play a crucial role in the transmission of this parasite to man via sandflies. The spleen and liver are the main target organs of L. infantum infection, but few studies have evaluated th
Autor:
Sérgio Caldas, Maria Terezinha Bahia, Ivo Santana Caldas, Tassiane Assíria Fontes Martins, Isabel Mayer de Andrade, Álvaro Fernando da Silva do Nascimento, Lívia de Figueiredo Diniz, Isabela Ribeiro, Ana Lia Mazzeti
Publikováno v:
PLoS ONE
Repositório Institucional da UFOP
Universidade Federal de Ouro Preto (UFOP)
instacron:UFOP
PLoS ONE, Vol 10, Iss 6, p e0128707 (2015)
Repositório Institucional da UFOP
Universidade Federal de Ouro Preto (UFOP)
instacron:UFOP
PLoS ONE, Vol 10, Iss 6, p e0128707 (2015)
The nitroheterocyclic drugs nifurtimox and benznidazole are first-line drugs available to treat Chagas disease; however, they have limitations, including long treatment courses and toxicity. Strategies to overcome these limitations include the identi