Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Álvaro Fernández Álvarez"'
Autor:
Manel Ouji, Guillaume Barnoin, Álvaro Fernández Álvarez, Jean-Michel Augereau, Catherine Hemmert, Françoise Benoit-Vical, Heinz Gornitzka
Publikováno v:
Molecules, Vol 25, Iss 12, p 2817 (2020)
The emergence of Plasmodium falciparum parasites, responsible for malaria disease, resistant to antiplasmodial drugs including the artemisinins, represents a major threat to public health. Therefore, the development of new antimalarial drugs or combi
Externí odkaz:
https://doaj.org/article/c69d09a16117434d96bdd6baaccbf70d
Autor:
Marie-Lise Maddelein, Olivier Cuvillier, Christian Bijani, Xing Wang, Catherine Hemmert, Xue Qin, Pierre-Yves Fortin, Heinz Gornitzka, Chen Zhang, Álvaro Fernández Álvarez, Guillaume Barnoin
Publikováno v:
Angewandte Chemie International Edition
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2020, 59 (29), pp.12062-12068. ⟨10.1002/anie.202002992⟩
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2020, 59 (29), pp.12062-12068. ⟨10.1002/anie.202002992⟩
A family of original bis(artemisinin-NHC)gold(I) complexes have been synthesized. These hybrid molecules combine two biological active motifs, an artemisinin derivative (DHA) and a cationic bis(NHC)gold(I) unit. One of these complexes, complex 2a, ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1441a3fb088bed031e824e6be5982da8
https://pubmed.ncbi.nlm.nih.gov/32304346
https://pubmed.ncbi.nlm.nih.gov/32304346
Autor:
Olivier Cuvillier, Catherine Hemmert, Xing Wang, Chen Zhang, Álvaro Fernández Álvarez, Pierre-Yves Fortin, Christian Bijani, Xue Qin, Guillaume Barnoin, Marie-Lise Maddelein, Heinz Gornitzka
Publikováno v:
Angewandte Chemie International Edition
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2020, 59 (29), pp.12062-12068. ⟨10.1002/anie.202002992⟩
Angewandte Chemie International Edition, 2020, 59 (29), pp.12062-12068. ⟨10.1002/anie.202002992⟩
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2020, 59 (29), pp.12062-12068. ⟨10.1002/anie.202002992⟩
Angewandte Chemie International Edition, 2020, 59 (29), pp.12062-12068. ⟨10.1002/anie.202002992⟩
A family of original bis(artemisinin-NHC)gold(I) complexes have been synthesized. These hybrid molecules combine two biological active motifs, an artemisinin derivative (DHA) and a cationic bis(NHC)gold(I) unit. One of these complexes, complex 2a, ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6514059b1678f18e5803ee064be1d16f
https://doi.org/10.26434/chemrxiv.11629113.v1
https://doi.org/10.26434/chemrxiv.11629113.v1
Autor:
Sandra Bourgeade Delmas, Alexis Valentin, Catherine Hemmert, Chen Zhang, Heinz Gornitzka, Álvaro Fernández Álvarez
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2018, 143, pp.1635-1643. ⟨10.1016/j.ejmech.2017.10.060⟩
European Journal of Medicinal Chemistry, 2018, 143, pp.1635-1643. ⟨10.1016/j.ejmech.2017.10.060⟩
European Journal of Medicinal Chemistry, Elsevier, 2018, 143, pp.1635-1643. ⟨10.1016/j.ejmech.2017.10.060⟩
European Journal of Medicinal Chemistry, 2018, 143, pp.1635-1643. ⟨10.1016/j.ejmech.2017.10.060⟩
International audience; A series of five new mononuclear neutral gold(I) complexes containing N-heterocyclic carbenes (NHCs) was synthesized and fully characterized by spectroscopic methods. The X-ray structures of four complexes are presented. These
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b605dac8b41c6019b0bf5e4666f3bea
https://hal.archives-ouvertes.fr/hal-01963517
https://hal.archives-ouvertes.fr/hal-01963517
Autor:
Heinz Gornitzka, Luca Boselli, Álvaro Fernández Álvarez, Jean-Michel Augereau, Françoise Benoit-Vical, Arba Pramundita Ramadani, Catherine Hemmert, Lucie Paloque
Publikováno v:
Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, Elsevier, 2016, 24 (13), pp.3075-3082. ⟨10.1016/j.bmc.2016.05.023⟩
Bioorganic and Medicinal Chemistry, 2016, 24 (13), pp.3075-3082. ⟨10.1016/j.bmc.2016.05.023⟩
Bioorganic and Medicinal Chemistry, Elsevier, 2016, 24 (13), pp.3075-3082. ⟨10.1016/j.bmc.2016.05.023⟩
Bioorganic and Medicinal Chemistry, 2016, 24 (13), pp.3075-3082. ⟨10.1016/j.bmc.2016.05.023⟩
International audience; A series of twenty five molecules, including imidazolium salts functionalized by N-, O- or S-containing groups and their corresponding cationic, neutral or anionic gold(I) complexes were evaluated on Plasmodium falciparum in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16caa6abf45b73261903b7d618891a40
https://hal.archives-ouvertes.fr/hal-01937596
https://hal.archives-ouvertes.fr/hal-01937596