Výsledky vyhledávání - "Álvaro F. García-Jiménez"

Akademický článek

BCG priming followed by a novel interleukin combination activates Natural Killer cells to selectively proliferate and become anti-tumour long-lived effectors

Autor: María-José Felgueres, Gloria Esteso, Álvaro F. García-Jiménez, Ana Dopazo, Nacho Aguiló, Carmen Mestre-Durán, Luis Martínez-Piñeiro, Antonio Pérez-Martínez, Hugh T. Reyburn, Mar Valés-Gómez

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)

Abstract The short-lived nature and heterogeneity of Natural Killer (NK) cells limit the development of NK cell-based therapies, despite their proven safety and efficacy against cancer. Here, we describe the biological basis, detailed phenotype and f

Externí odkaz: https://doaj.org/article/bd24417e2d61481aba2a499fb276ab1b

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Akademický článek

Elevated levels of cell-free NKG2D-ligands modulate NKG2D surface expression and compromise NK cell function in severe COVID-19 disease

Autor: Daniel Fernández-Soto, Álvaro F. García-Jiménez, José M. Casasnovas, Mar Valés-Gómez, Hugh T. Reyburn

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

IntroductionIt is now clear that coronavirus disease 19 (COVID-19) severity is associated with a dysregulated immune response, but the relative contributions of different immune cells is still not fully understood. SARS CoV-2 infection triggers marke

Externí odkaz: https://doaj.org/article/393746ad871c479da14e43b119e05dbb

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Akademický článek

BCG-activation of leukocytes is sufficient for the generation of donor-independent innate anti-tumor NK and γδ T-cells that can be further expanded in vitro

Autor: Gloria Esteso, María José Felgueres, Álvaro F. García-Jiménez, Christina Reyburn-Valés, Alberto Benguría, Enrique Vázquez, Hugh T. Reyburn, Nacho Aguiló, Carlos Martín, Eugenia Puentes, Ingrid Murillo, Esteban Rodríguez, Mar Valés-Gómez

Publikováno v: OncoImmunology, Vol 12, Iss 1 (2023)

ABSTRACTBacillus Calmette-Guérin (BCG), the nonpathogenic Mycobacterium bovis strain used as tuberculosis vaccine, has been successfully used as treatment for non-muscle invasive bladder cancer for decades, and suggested to potentiate cellular and h

Externí odkaz: https://doaj.org/article/d8013a98d0e348c39add8c2094c07125

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BCG-activation of leukocytes is sufficient for the generation of donor-independent innate anti-tumor NK and γδ T-cells that can be further expanded

Publikováno v: Oncoimmunology. 12(1)

Bacillus Calmette-Guérin (BCG), the nonpathogenic Mycobacterium bovis strain used as tuberculosis vaccine, has been successfully used as treatment for non-muscle invasive bladder cancer for decades, and suggested to potentiate cellular and humoral i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a9347c310a9c290a50ae736a4d4dc0f
https://pubmed.ncbi.nlm.nih.gov/36567803

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