Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Álvaro Curiel-García"'
Autor:
Beatriz Parejo-Alonso, Alba Royo-García, Pilar Espiau-Romera, Sarah Courtois, Álvaro Curiel-García, Sladjana Zagorac, Isabel Villaoslada, Kenneth P. Olive, Christopher Heeschen, Patricia Sancho
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 158, Iss , Pp 114162- (2023)
Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive disease characterized by its metastatic potential and chemoresistance. These traits are partially attributable to the highly tumorigenic pancreatic cancer stem cells (PaCSCs). Interes
Externí odkaz:
https://doaj.org/article/506d1cc2b5904b518e528ab51caf3893
Autor:
Barbara Oldrini, Álvaro Curiel-García, Carolina Marques, Veronica Matia, Özge Uluçkan, Osvaldo Graña-Castro, Raul Torres-Ruiz, Sandra Rodriguez-Perales, Jason T. Huse, Massimo Squatrito
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Accurate recapitulation of human disease in animal models requires generation of complex and heterogeneous genetic variation. Here the authors combine RCAS-TVA with CRISPR-Cas9 to generate mouse models of cancer.
Externí odkaz:
https://doaj.org/article/fd236016877346748003cdfce0070291
Autor:
Massimo Squatrito, Fátima Al-Shahrour, Scott W. Lowe, Lucía Zhu, Marcos Galán-Ganga, Alberto J. Schuhmacher, Javier Perales-Patón, Paula Nogales, Álvaro Curiel-García, Miguel Jiménez-Alcázar
Glioblastoma (GBM) is the most frequent and aggressive primary tumor type in the central nervous system in adults. Resistance to chemotherapy remains one of the major obstacles in GBM treatment. Identifying and overcoming the mechanisms of therapy re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43115107f15d3f842e939c69d8b4576d
https://doi.org/10.1158/1535-7163.c.6543511.v1
https://doi.org/10.1158/1535-7163.c.6543511.v1
Autor:
Massimo Squatrito, Fátima Al-Shahrour, Scott W. Lowe, Lucía Zhu, Marcos Galán-Ganga, Alberto J. Schuhmacher, Javier Perales-Patón, Paula Nogales, Álvaro Curiel-García, Miguel Jiménez-Alcázar
Screening results U251 TMZ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f675ddfc171650e7cca1b27ca970dea
https://doi.org/10.1158/1535-7163.22522864.v1
https://doi.org/10.1158/1535-7163.22522864.v1
Autor:
Massimo Squatrito, Fátima Al-Shahrour, Scott W. Lowe, Lucía Zhu, Marcos Galán-Ganga, Alberto J. Schuhmacher, Javier Perales-Patón, Paula Nogales, Álvaro Curiel-García, Miguel Jiménez-Alcázar
Combined supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09faa93274a8f3ec1648652d9437fa29
https://doi.org/10.1158/1535-7163.22522870.v1
https://doi.org/10.1158/1535-7163.22522870.v1
Autor:
Beatriz Parejo-Alonso, Alba Royo-García, Pilar Espiau-Romera, Sarah Courtois, Álvaro Curiel-García, Sladjana Zagorac, Isabel Villaoslada, Kenneth P. Olive, Christopher Heeschen, Patricia Sancho
Publikováno v:
Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 158
Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive disease characterized by its metastatic potential and chemoresistance. These traits are partially attributable to the highly tumorigenic pancreatic cancer stem cells (PaCSCs). Interes
Autor:
Beatriz Parejo-Alonso, Alba Royo-García, Pilar Espiau-Romera, Sarah Courtois, Álvaro Curiel-García, Sladjana Zagorac, Isabel Villaoslada, Kenneth P. Olive, Christopher Heeschen, Patricia Sancho
Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive disease characterized by its metastatic potential and chemoresistance. These traits are partially attributable to the highly tumorigenic pancreatic cancer stem cells (PaCSCs). Interes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8a4582a0511c6ef69a7fd6500ca85d4
https://doi.org/10.1101/2022.08.29.505637
https://doi.org/10.1101/2022.08.29.505637
Autor:
Marcos Galán-Ganga, Alberto J. Schuhmacher, Paula Nogales, Fatima Al-Shahrour, Miguel Jiménez-Alcázar, Lucía Zhu, Javier Perales-Patón, Scott W. Lowe, Álvaro Curiel-García, Massimo Squatrito
Publikováno v:
Mol Cancer Ther
Glioblastoma (GBM) is the most frequent and aggressive primary tumor type in the central nervous system in adults. Resistance to chemotherapy remains one of the major obstacles in GBM treatment. Identifying and overcoming the mechanisms of therapy re
Autor:
Kenneth P. Olive, Álvaro Curiel-García
Publikováno v:
Trends in molecular medicine. 25(5)
Genetically engineered mouse models have revolutionized the study of pancreatic cancer, but have several technical and practical limitations. A new adeno-associated virus (AAV)-driven somatic genome-editing model of pancreatic ductal adenocarcinoma r
Autor:
Ingo K. Mellinghoff, Craig M. Bielski, Maryam Pourmaleki, Paolo Codega, Maria Stella Carro, Massimo Squatrito, Barry S. Taylor, Álvaro Curiel-García, Paul Tempst, Daniel Rohle, John Blenis, Travis J. Hollmann, Barbara Oldrini, Igor Vivanco, Carl Campos, Hediye Erdjument-Bromage, Wan-Ying Hsieh, Marc K. Rosenblum, Christian Grommes
Publikováno v:
Repisalud
Instituto de Salud Carlos III (ISCIII)
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications
Instituto de Salud Carlos III (ISCIII)
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications
Transport of macromolecules through the nuclear pore by importins and exportins plays a critical role in the spatial regulation of protein activity. How cancer cells co-opt this process to promote tumorigenesis remains unclear. The epidermal growth f