Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Álvaro Cuesta-Domínguez"'
Autor:
Álvaro Cuesta-Domínguez, Mara Ortega, Cristina Ormazábal, Matilde Santos-Roncero, Marta Galán-Díez, Juan Luis Steegmann, Ángela Figuera, Eva Arranz, José Luis Vizmanos, Juan A Bueren, Paula Río, Elena Fernández-Ruiz
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32451 (2012)
Chromosomal translocations in tumors frequently produce fusion genes coding for chimeric proteins with a key role in oncogenesis. Recent reports described a BCR-JAK2 fusion gene in fatal chronic and acute myeloid leukemia, but the functional behavior
Externí odkaz:
https://doaj.org/article/bc52bc3a930b499690d3aaf99af551e0
Autor:
Edlira Hoxha, Catherine Diefenbach, Yutong Zhang, Adriana Heguy, Anastasia N. Tikhonova, Stavroula Kousteni, Kishor K. Sivaraj, Aristotelis Tsirigos, Hai Hu, Ralf H. Adams, Igor Dolgalev, Aris N. Economides, Matthew T. Witkowski, Ilseyar Akhmetzyanova, Michael C. Gutkin, Jason M. Butler, Maria Guillamot, Álvaro Cuesta-Domínguez, Jie Gao, Sandra Pinho, Hua Zhong, Paul S. Frenette, Rahul Satija, David R. Fooksman, Christian Marier, Iannis Aifantis
Publikováno v:
Nature
The molecular complexity of the bone marrow (BM) microenvironment and its response to stress are incompletely understood, despite its key role in the regulation of hematopoiesis. Here we map the transcriptional landscape of BM vascular, perivascular,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd188ba243ed1779b2b761ac1b0f86e2
https://doi.org/10.1038/s41586-019-1104-8
https://doi.org/10.1038/s41586-019-1104-8
Autor:
Rocío Baños, Elena Almarza, Miguel Ángel Martín-Rey, Elena Fernández-Ruiz, Irene Bodega-Mayor, Paloma Martín-Acosta, Lara Álvarez, Matilde Santos-Roncero, María Luisa Gaspar, Juan A. Bueren, Paula Río, Álvaro Cuesta-Domínguez, Begoña Díez, Diego Leon-Rico
Publikováno v:
The Journal of Pathology. 236:219-228
BCR-JAK2 is an infrequent gene fusion found in chronic/acute, myeloid/lymphoid Philadelphia chromosome-negative leukaemia. In this study, we demonstrated that in vivo expression of BCR-JAK2 in mice induces neoplasia, with fatal consequences. Transpla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b90e73a05e3944f92f5e70766f15121
https://doi.org/10.1002/path.4513
https://doi.org/10.1002/path.4513
Autor:
Aris N. Economides, Hua Zhong, Edlira Hoxha, Jie Gao, Rahul Satija, Catherine Diefenbach, Christian Marier, Anastasia N. Tikhonova, Kishor K. Sivaraj, Maria Guillamot, Iannis Aifantis, Ilseyar Akhmetzyanova, Igor Dolgalev, Adriana Heguy, Yutong Zhang, Aristotelis Tsirigos, Jason M. Butler, Ralf H. Adams, David R. Fooksman, Hai Hu, Michael C. Gutkin, Stavroula Kousteni, Álvaro Cuesta-Domínguez, Paul S. Frenette, Sandra Pinho, Matthew T. Witkowski
Publikováno v:
Nature. 572:E6-E6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e91c95e5e8ea2735d3fd0687977ea13
https://doi.org/10.1038/s41586-019-1394-x
https://doi.org/10.1038/s41586-019-1394-x
Publikováno v:
Cold Spring Harb Perspect Med
Hematopoietic stem cells (HSCs) interact dynamically with an intricate network of cells in the bone marrow (BM) microenvironment or niche. These interactions provide instructive cues that influence the production and lineage determination of differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f91f3912ae84ae0d84594cd205856d
https://doi.org/10.1101/cshperspect.a031328
https://doi.org/10.1101/cshperspect.a031328
Autor:
Álvaro, Cuesta-Domínguez, Diego, León-Rico, Lara, Álvarez, Begoña, Díez, Irene, Bodega-Mayor, Rocío, Baños, Miguel Ángel, Martín-Rey, Matilde, Santos-Roncero, María Luisa, Gaspar, Paloma, Martín-Acosta, Elena, Almarza, Juan A, Bueren, Paula, Río, Elena, Fernández-Ruiz
Publikováno v:
The Journal of pathology. 236(2)
BCR-JAK2 is an infrequent gene fusion found in chronic/acute, myeloid/lymphoid Philadelphia chromosome-negative leukaemia. In this study, we demonstrated that in vivo expression of BCR-JAK2 in mice induces neoplasia, with fatal consequences. Transpla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::575c61fba5d5dffbc08b848be29e0cf8
https://pubmed.ncbi.nlm.nih.gov/25664618
https://pubmed.ncbi.nlm.nih.gov/25664618
Autor:
Elena Fernández-Ruiz, Juan Luis Steegmann, José L. Vizmanos, Marta Galán-Díez, Álvaro Cuesta-Domínguez, Matilde Santos-Roncero, E. Arranz, Mara Ortega, Cristina Ormazábal, A Figuera, Juan A. Bueren, Paula Río
Publikováno v:
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
PLoS ONE
PLoS ONE, Vol 7, Iss 2, p e32451 (2012)
instname
PLoS ONE
PLoS ONE, Vol 7, Iss 2, p e32451 (2012)
Chromosomal translocations in tumors frequently produce fusion genes coding for chimeric proteins with a key role in oncogenesis. Recent reports described a BCR-JAK2 fusion gene in fatal chronic and acute myeloid leukemia, but the functional behavior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3faa2a371db2bee5a7e557c765061e69
http://hdl.handle.net/10486/666893
http://hdl.handle.net/10486/666893
Autor:
Jesús Pla, Mara Ortega, Marta Galán-Díez, Álvaro Cuesta-Domínguez, José M. Casasnovas, Leonor Kremer, Angel L. Corbí, Diego Serrano-Gómez, David M. Arana, Elena Fernández-Ruiz
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Innate immunity to Candida albicans depends upon the recognition of molecular patterns on the fungal cell wall. However, the masking of major components such as β-glucan seems to be a mechanism that fungi have evolved to avoid immune cell recognitio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd3a0dabfb9d5d333b740a7956ebbc56
http://hdl.handle.net/10261/82243
http://hdl.handle.net/10261/82243
Autor:
Marta Galán-Díez, Álvaro Cuesta-Domínguez, Mara Ortega, María Ángeles Figuera, Matilde Santos-Roncero, Juan A. Bueren, Peter P. Sayeski, Paula Río, Jaqueline Sayyah, Juan Luis Steegmann, E. Arranz, Cristina Ormazábal, Elena Fernández-Ruiz, José L. Vizmanos
Publikováno v:
Blood. 114:4683-4683
Abstract 4683 Chromosomal translocations in human tumors frequently produce fusion genes whose chimeric protein products play an essential role in oncogenesis. Recent reports have found a BCR-JAK2 fusion gene in cases of chronic or acute myeloid leuk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d88aedbd8394b310f9d7d7ae23bea59
https://doi.org/10.1182/blood.v114.22.4683.4683
https://doi.org/10.1182/blood.v114.22.4683.4683