Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Álvaro Chiner‐Oms"'
Autor:
Chantal Renau-Mínguez, Paula Herrero-Abadía, Paula Ruiz-Rodriguez, Vicente Sentandreu, Eduard Torrents, Álvaro Chiner-Oms, Manuela Torres-Puente, Iñaki Comas, Esther Julián, Mireia Coscolla
Publikováno v:
Frontiers in Microbiology, Vol 13 (2023)
Mycobacterium brumae is a rapid-growing, non-pathogenic Mycobacterium species, originally isolated from environmental and human samples in Barcelona, Spain. Mycobacterium brumae is not pathogenic and it’s in vitro phenotype and immunogenic properti
Externí odkaz:
https://doaj.org/article/aaa5d4d1b2d94d728f599ae1c0880f1d
Autor:
Victoria Furió, Miguel Moreno-Molina, Álvaro Chiner-Oms, Luis M. Villamayor, Manuela Torres-Puente, Iñaki Comas
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Victoria Furió et al. apply functional genomics and evolutionary analyses to the study of antibiotic resistance in tuberculosis. Focusing on isoniazid resistance and using genomic data from clinical strains, they identify novel candidate genes with
Externí odkaz:
https://doaj.org/article/19f431d7b8e34a2ebb1131dafa6b61b8
Autor:
Antoni E. Bordoy, Xavier Vallès, Anna Not, Álvaro Chiner-Oms, Verónica Saludes, Judit Torres Cervós, Anna Roset Roig, Concha Juan-Andres, Helena Sureda, Vanessa Pardo-Amil, Irene García, Gemma Guitart Rossell, Laura Cambra Cibeira, Cristina Casañ, Montserrat Giménez, Ignacio Blanco, Manuela Torres-Puente, Irving Cancino-Muñoz, Fernando González-Candelas, Iñaki Comas, Elisa Martró
Publikováno v:
mSphere, Vol 7, Iss 6 (2022)
ABSTRACT Limiting outbreaks in long-term care facilities (LTCFs) is a cornerstone strategy to avoid an excess of COVID-19-related morbidity and mortality and to reduce its burden on the health system. We studied a large outbreak that occurred at an L
Externí odkaz:
https://doaj.org/article/bc08f6bb060544eb9f1d6ce53f2a8303
Autor:
Jeremy Sousa, Baltazar Cá, Ana Raquel Maceiras, Luisa Simões-Costa, Kaori L. Fonseca, Ana Isabel Fernandes, Angélica Ramos, Teresa Carvalho, Leandro Barros, Carlos Magalhães, Álvaro Chiner-Oms, Henrique Machado, Maria Isabel Veiga, Albel Singh, Rui Pereira, António Amorim, Jorge Vieira, Cristina P. Vieira, Apoorva Bhatt, Fernando Rodrigues, Pedro N. S. Rodrigues, Sebastien Gagneux, António Gil Castro, João Tiago Guimarães, Helder Novais Bastos, Nuno S. Osório, Iñaki Comas, Margarida Saraiva
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Some strains of Mycobacterium tuberculosis seem to be able to avoid host defense systems. Here the authors stratify patients by severity of tuberculosis and find correlations with the level of IL-1β production by macrophages exposed to these isolate
Externí odkaz:
https://doaj.org/article/9739f22b341d45e887d3375a55c3b04a
Autor:
Juan José Badiola, Alicia Otero, Eloisa Sevilla, Belén Marín, Mirta García Martínez, Marina Betancor, Diego Sola, Sonia Pérez Lázaro, Jenny Lozada, Carolina Velez, Álvaro Chiner-Oms, Iñaki Comas, Irving Cancino-Muñoz, Eva Monleón, Marta Monzón, Cristina Acín, Rosa Bolea, Bernardino Moreno
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2022)
Farmed minks have been reported to be highly susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and may represent a risk to humans. In this study, we describe the first outbreak of SARS-CoV-2 occurred on a mink farm in Spain,
Externí odkaz:
https://doaj.org/article/90470ad06c7b46168c2f9e554e3d27dd
Autor:
Paula Ruiz-Rodriguez, Clara Francés-Gómez, Álvaro Chiner-Oms, Mariana G. López, Santiago Jiménez-Serrano, Irving Cancino-Muñoz, Paula Ruiz-Hueso, Manuela Torres-Puente, Maria Alma Bracho, Giuseppe D’Auria, Llúcia Martinez-Priego, Manuel Guerreiro, Marta Montero-Alonso, María Dolores Gómez, José Luis Piñana, Fernando González-Candelas, Iñaki Comas, Alberto Marina, Ron Geller, Mireia Coscolla
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT We have detected two mutations in the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at amino acid positions 1163 and 1167 that appeared independently in multiple transmission clusters and different genetic bac
Externí odkaz:
https://doaj.org/article/c89a80d9f2994db38337a44de2b57718
Autor:
Álvaro Chiner-Oms, Michael Berney, Christine Boinett, Fernando González-Candelas, Douglas B. Young, Sebastien Gagneux, William R. Jacobs, Julian Parkhill, Teresa Cortes, Iñaki Comas
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
A variety of biological differences exist between strains and phylogenetic lineages in the Mycobacterium tuberculosis complex (MTBC). Here, the authors perform RNAseq and methylome analysis of the main clades of the MTBC and show variation in transcr
Externí odkaz:
https://doaj.org/article/420da98a568148859292e03efed69a7b
Autor:
Juan Domínguez, Fermín Acosta, Laura Pérez-Lago, Dilcia Sambrano, Victoria Batista, Carolina De La Guardia, Estefanía Abascal, Álvaro Chiner-Oms, Iñaki Comas, Prudencio González, Jaime Bravo, Pedro Del Cid, Samantha Rosas, Patricia Muñoz, Amador Goodridge, Darío García de Viedma
Publikováno v:
Emerging Infectious Diseases, Vol 25, Iss 3, Pp 507-514 (2019)
Systematic molecular/genomic epidemiology studies for tuberculosis surveillance cannot be implemented in many countries. We selected Panama as a model for an alternative strategy. Mycobacterial interspersed repetitive unit–variable-number tandem-re
Externí odkaz:
https://doaj.org/article/f0e5c7c2460a46f9bc4acb77874a1996
Autor:
Francisco José Martínez-Martínez, Arsenia J Massinga, Áuria De Jesus, Rita M Ernesto, Pablo Cano-Jiménez, Álvaro Chiner-Oms, Inmaculada Gómez-Navarro, Marina Guillot-Fernández, Caterina Guinovart, António Sitoe, Delfino Vubil, Rubão Bila, Rufino Gujamo, Sónia Enosse, Santiago Jiménez-Serrano, Manuela Torres-Puente, Iñaki Comas, Inácio Mandomando, Mariana G López, Alfredo Mayor
9 hojas, 4 figuras, 1 tabla. Demographic data of the participants are available in the appendix (pp 40–42). Genome sequences are publicly available on GISAID. All scripts used for the analysis, and beta and delta subtree files are publicly availabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::999fd1223e02105223ec7d5cdf6969d6
http://hdl.handle.net/10261/310456
http://hdl.handle.net/10261/310456
Autor:
Marta Herranz, Ilva Pole, Iveta Ozere, Álvaro Chiner-Oms, Miguel Martínez-Lirola, Felipe Pérez-García, Paloma Gijón, María Jesús Ruiz Serrano, Laura Clotet Romero, Oscar Cuevas, Iñaki Comas, Emilio Bouza, Laura Pérez-Lago, Darío García-de-Viedma
Publikováno v:
Frontiers in Microbiology, Vol 8 (2018)
Background:Mycobacterium tuberculosis (MTB) has limited ability to acquire variability. Analysis of its microevolution might help us to evaluate the pathways followed to acquire greater infective success. Whole-genome sequencing (WGS) in the analysis
Externí odkaz:
https://doaj.org/article/8a4804804a2f4065abd986effec3f540