Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Álvaro Aranguren-Ibáñez"'
Autor:
Serdal Gungor, Yavuz Oktay, Semra Hiz, Álvaro Aranguren-Ibáñez, Ipek Kalafatcilar, Ahmet Yaramis, Ezgi Karaca, Uluc Yis, Ece Sonmezler, Burcu Ekinci, Mahmut Aslan, Elmasnur Yilmaz, Bilge Özgör, Sunitha Balaraju, Nora Szabo, Steven Laurie, Sergi Beltran, Daniel G. MacArthur, Denisa Hathazi, Ana Töpf, Andreas Roos, Hanns Lochmuller, Isabelle Vernos, Rita Horvath
Publikováno v:
iScience, Vol 24, Iss 1, Pp 101948- (2021)
Summary: Microtubules help building the cytoskeleton of neurons and other cells. Several components of the gamma-tubulin (γ-tubulin) complex have been previously reported in human neurodevelopmental diseases. We describe two siblings from a consangu
Externí odkaz:
https://doaj.org/article/2e92aa318b974cfabac7dd6e6609004b
Autor:
Ritobrata Ghose, Álvaro Aranguren-Ibáñez, Niccolò Arecco, Diego Balboa, Marc Bataller, Sergi Beltran, Hannah Benisty, Angèle Bénard, Edgar Bernardo, Sílvia Carbonell Sala, Eloi Casals, Ludovica Ciampi, Livia Condemi, Alberto Corvó, Marta Cosín-Tomás, Mirabai Cuenca-Ardura, Juan Manuel Duran Serrano, María Isabel Espejo Díaz, Marcos Fernandez Callejo, Antoni Gañez-Zapater, Raquel Garcia-Castellanos, Romina Garrido, Gil Henkin, Toni Hermoso Pulido, Xavier Hernandez-Alias, Jorge Herrero Vicente, Matthew Ingham, Wei Ming Lim, Sílvia Llonch, Elena Marmesat Bertoli, Irene Miguel-Escalada, Ariadna Montero-Blay, Cristina Navarrete Hernández, Maria Victoria Neguembor, Róisín-Ana Ní Chárthaigh, Natalia Pardo-Lorente, Laura Pascual-Reguant, Sílvia Pérez-Lluch, Reyes Perza, Martina Pesaresi, Daniel Picó Amador, Paula Pifarré, Davide Piscia, Marcos Plana-Carmona, Julia Ponomarenko, Leandro Radusky, Ezequiel Rivero, Malgorzata Rogalska, Guillem Torcal Garcia, José Wojnacki
Publikováno v:
F1000Research, Vol 9 (2020)
The COVID-19 pandemic has posed and is continuously posing enormous societal and health challenges worldwide. The research community has mobilized to develop novel projects to find a cure or a vaccine, as well as to contribute to mass testing, which
Externí odkaz:
https://doaj.org/article/a31f23efbb70401e91a65643d3267f89
Autor:
Alicia Guasch, Álvaro Aranguren-Ibáñez, Rosa Pérez-Luque, David Aparicio, Sergio Martínez-Høyer, M Carmen Mulero, Eva Serrano-Candelas, Mercè Pérez-Riba, Ignacio Fita
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134569 (2015)
A limited repertoire of PPP family of serine/threonine phosphatases with a highly conserved catalytic domain acts on thousands of protein targets to orchestrate myriad central biological roles. A major structural reorganization of human calcineurin,
Externí odkaz:
https://doaj.org/article/64e2ba1d62a94d6d85dbf07c266b1bd4
Autor:
Eva Serrano-Candelas, Domènec Farré, Álvaro Aranguren-Ibáñez, Sergio Martínez-Høyer, Mercè Pérez-Riba
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85539 (2014)
Recently there has been much interest in the Regulators of Calcineurin (RCAN) proteins which are important endogenous modulators of the calcineurin-NFATc signalling pathway. They have been shown to have a crucial role in cellular programmes such as t
Externí odkaz:
https://doaj.org/article/2a2f40a56406438982678284050f8824
Autor:
Uluç Yiş, Denisa Hathazi, Serdal Güngör, Ezgi Karaca, Ipek Kalafatcilar, Ahmet Yaramis, Ece Sonmezler, Nóra Zs Szabó, Ana Töpf, Elmasnur Yilmaz, Daniel G. MacArthur, Andreas Roos, Burcu Ekinci, Sunitha Balaraju, Steven Laurie, Bilge Özgör, Rita Horvath, Mahmut Aslan, Isabelle Vernos, Yavuz Oktay, Semra Hiz, Hanns Lochmüller, Sergi Beltran, Álvaro Aranguren-Ibáñez
Publikováno v:
iScience
iScience, Vol 24, Iss 1, Pp 101948-(2021)
iScience, Vol 24, Iss 1, Pp 101948-(2021)
Summary Microtubules help building the cytoskeleton of neurons and other cells. Several components of the gamma-tubulin (γ-tubulin) complex have been previously reported in human neurodevelopmental diseases. We describe two siblings from a consangui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7396541582b104f4e888201af99ec4d8
Autor:
Alicia Guasch, Álvaro Aranguren-Ibáñez, Mercè Pérez-Riba, Juan Carlos Paniagua, Ignacio Fita, Atilla Biçer, Saeed Chashmniam, João M.C. Teixeira, Miquel Pons
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Calcineurin is an essential calcium‐activated serine/threonine phosphatase. The six NMR‐observable methionine methyl groups in the catalytic domain of human calcineurin Aα (CNA) were assigned and used as reporters of the presence of potential ci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd8c6bf7e5f1dadb883893f9d7ef09a
http://hdl.handle.net/10261/201404
http://hdl.handle.net/10261/201404
Autor:
Mercè Pérez-Riba, Javier Garcia-Garcia, Eva Serrano-Candelas, Jordi Vilardell, Baldo Oliva, Álvaro Aranguren-Ibáñez, Fernando Aguado, Emilio Itarte, Virginia Nunes, Sergio Martínez-Hoyer
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1833:2311-2321
Cyclosporine A and FK506 produce immunosuppression by blocking calcineurin phosphatase activity and consequently activation of cytosolic Nuclear Factor of Activated T-cell (NFATc) transcription factor. Due to the chronic toxicity associated with thei
Autor:
Leonardo Pardo, Mercè Pérez-Riba, Minos-Timotheos Matsoukas, Teresa Lozano, Virginia Nunes, Juan José Lasarte, Álvaro Aranguren-Ibáñez
Publikováno v:
Science Signaling. 8
Calcineurin (CN), a serine and threonine protein phosphatase that depends on Ca(2+) and calmodulin for its activity, is the target of the immunosuppressant drugs cyclosporin A (CsA) and tacrolimus (FK506). CN dephosphorylates and activates members of
Autor:
Sonia Sole-Sanchez, Sergio Martínez-Hoyer, Mercè Pérez-Riba, Gloria Soldevila, Eva Serrano-Candelas, Melanie April Pritchard, Anna Aubareda, Jaume Adan, Germán R. Alemán-Muench, Álvaro Aranguren-Ibáñez
Publikováno v:
Biochemical and biophysical research communications. 460(2)
Cooperation between calcineurin (CN)-NFATc and RAF-MEK-ERK signaling pathways is essential in thymocyte positive selection. It is known that the Regulators of Calcineurin (RCAN) proteins can act either facilitating or suppressing CN-dependent signali
Autor:
M. Carmen Mulero, Alicia Guasch, Sergio Martínez-Hoyer, Mercè Pérez-Riba, Rosa Pérez-Luque, Eva Serrano-Candelas, David Aparicio, Ignacio Fita, Álvaro Aranguren-Ibáñez
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
PLoS ONE
PLoS ONE, Vol 10, Iss 8, p e0134569 (2015)
Digital.CSIC. Repositorio Institucional del CSIC
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
PLoS ONE
PLoS ONE, Vol 10, Iss 8, p e0134569 (2015)
Digital.CSIC. Repositorio Institucional del CSIC
Copyright: © 2015 Guasch et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b19d354c0078d1b5e8b2dd07a8392fd3
http://hdl.handle.net/2445/96367
http://hdl.handle.net/2445/96367