Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ákos Urai"'
Autor:
Ferenc Ötvös, Edina Szűcs, Ákos Urai, István Köteles, Pál T. Szabó, Zsuzsanna Katalin Varga, Dávid Gombos, Sándor Hosztafi, Sándor Benyhe
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Opiate alkaloids and their synthetic derivatives are still widely used in pain management, drug addiction, and abuse. To avoid serious side effects, compounds with properly designed pharmacological profiles at the opioid receptor subtypes ar
Externí odkaz:
https://doaj.org/article/b5b57eb3746046f899b96dbae84ce431
Autor:
Ákos Urai, Levente Szőcs, Sándor Hosztafi, Balázs Komjáti, Amanda Hunkele, Gavril W. Pasternak, Valerie Le Rouzic, Susruta Majumdar, András Váradi
Publikováno v:
MedChemComm. 8:152-157
It was previously reported that 6β-aminomorphinan derivatives show high affinity for opiate receptors. Novel 6β-heteroarylamidomorphinanes were designed based on the MOR selective antagonist NAP. The 6β-aminomorphinanes were prepared by stereosele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec0a450ba678464ae6606725bcf84766
https://doi.org/10.1039/c6md00450d
https://doi.org/10.1039/c6md00450d
Autor:
Gergő Tóth, Ákos Urai, Sándor Hosztafi, Valerie Le Rouzic, Gavril W. Pasternak, András Váradi, Steven G. Grinnell, Susruta Majumdar, Béla Noszál
Publikováno v:
European Journal of Medicinal Chemistry. 69:786-789
Aminomorphinans are a relatively young class of opioid drugs among which substances of high in vitro efficacy and favorable in vivo action are found. We report the synthesis and pharmacological evaluation of novel 6β-acylaminomorphinans. 6β-Morphin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82ac7b05aa053ec1cfed17e0952658b4
https://doi.org/10.1016/j.ejmech.2013.09.031
https://doi.org/10.1016/j.ejmech.2013.09.031
Autor:
József Nagy, Balázs Komjáti, Benjámin Kováts, Peter Horvath, Ákos Urai, József Kökösi, Sándor Hosztafi
Publikováno v:
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 155
B3LYP is one of the most widely used functional for the prediction of electronic circular dichroism spectra, however if the studied molecule contains aromatic nitro group computations may fail to produce reliable results. A test set of molecules of k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea8b2584c414af579908838de5128327
https://pubmed.ncbi.nlm.nih.gov/26583523
https://pubmed.ncbi.nlm.nih.gov/26583523