Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ákos Hornung"'
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 18, p 4455 (2019)
Altered cell surface glycosylation in congenital and acquired diseases has been shown to affect cell differentiation and cellular responses to external signals. Hence, it may have an important role in immune regulation; however, T cell surface glycos
Externí odkaz:
https://doaj.org/article/13cdf942dae443519a2d5a3e2e07a617
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 18, p 4455 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 18
International Journal of Molecular Sciences
Volume 20
Issue 18
Altered cell surface glycosylation in congenital and acquired diseases has been shown to affect cell differentiation and cellular responses to external signals. Hence, it may have an important role in immune regulation
however, T cell surface gl
however, T cell surface gl
Autor:
Andrea Blaskó, Ildikó Makra, Nandor Gabor Than, Éva Kriston-Pál, Roberta Fajka-Boja, Ferenc Uher, Enikő Szabó, Ágnes Czibula, Veronika S. Urbán, Éva Monostori, Gábor J. Szebeni, Ákos Hornung
Publikováno v:
Cytotherapy. 18:360-370
BACKGROUND AIMS: Mesenchymal stromal cells (MSCs) have powerful immunosuppressive activity. This function of MSCs is attributed to plethora of the expressed immunosuppressive factors, such as galectin-1 (Gal-1), a pleiotropic lectin with robust anti-
Publikováno v:
Poster session 5: Innate and adaptive immunity.
Glycosylation (sugar code) is frequently altered on the surface of various cells in patients with immune-mediated diseases resulting in changes in signal transduction and metabolic control. However, alteration of glycosylation patterns of T cells has
Autor:
Magdolna Deák, Dmytro Demydenko, Enikő Szabó, Julianna Novák, László Kovács, Ágnes Czibula, Éva Monostori, Éva Kriston-Pál, Roberta Fajka-Boja, Ákos Hornung
Publikováno v:
Immunobiology. 220:483-489
Secreted, extracellular galectin-1 (exGal-1) but not intracellular Gal-1 (inGal-1) has been described as a strong immunosuppressive protein due to its major activity of inducing apoptosis of activated T-cells. It has previously been reported that T-c
Publikováno v:
Immune regulation.
Background We have previously shown that activated T-cells from systemic lupus erythematosus (SLE) patients are resistant to the apoptotic effects of galectin-1 (Gal-1), an endogenous immunoregulatory lectin. The expression of de novo synthesised, in
Systemic lupus erythematosus in the light of the regulatory effects of galectin-1 on T-cell function
Publikováno v:
Lupus. 26(4)
Galectin-1 is an endogenous immunoregulatory lectin-type protein. Its most important effects are the inhibition of the differentiation and cytokine production of Th1 and Th17 cells, and the induction of apoptosis of activated T-cells. Galectin-1 has
Autor:
Roberta Fajka-Boja, Erika Szabó, Kriston-Pá É, Magdolna Deák, László Kovács, Ágnes Czibula, Julianna Novák, Ákos Hornung, Éva Monostori
Publikováno v:
Annals of the Rheumatic Diseases. 74:A19.1-A19
Background and objectives Secreted, extracellular galectin-1 (exGal-1) but not intracellular Gal-1 (inGal-1) has been described as a strong immunosuppressive protein due to its major activity of inducing apoptosis of activated T-cells. It has previou