Výsledky vyhledávání - "Áine M. Kelly"

Akademický článek

Renewing an undergraduate science curriculum for the 21st century

Autor: Louise McAteer, Joseph Roche, Áine M. Kelly

Publikováno v: Frontiers in Education, Vol 8 (2023)

IntroductionThe rapid pace of technological advancement, globalisation, and complex socio-economic challenges facing 21st-century society necessitates a rethinking of undergraduate science education. Undergraduate science curriculum reform is essenti

Externí odkaz: https://doaj.org/article/58cf75dcaa9e4a3f8bc8d64b4a9d1130

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Akademický článek

Acute high-intensity aerobic exercise affects brain-derived neurotrophic factor in mild cognitive impairment: a randomised controlled study

Autor: Emer M Guinan, Kate E Devenney, Áine M Kelly, Bibiana C Mota, Cathal Walsh, Marcel Olde Rikkert, Stefan Schneider, Brian Lawlor

Publikováno v: BMJ Open Sport & Exercise Medicine, Vol 5, Iss 1 (2019)

Objective To investigate the brain-derived neurotrophic factor (BDNF) and cognitive response to a short bout of high-intensity aerobic exercise in older adults with mild cognitive impairment (MCI).Methods Participants were randomised to one of two te

Externí odkaz: https://doaj.org/article/118b32f30c964a548e6d392549fe5eae

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Exercise-induced modulation of neuroinflammation in ageing

Autor: Zsuzsanna Barad, Joana Augusto, Áine M. Kelly

Publikováno v: The Journal of physiologyReferences.

Optimal performance of the central nervous system (CNS) depends on dynamic, multidirectional communication between different cell types both within and without the CNS to maintain the homeostatic environment. Ageing, in turn, is associated with CNS d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb1056e278d187df123e38c3175eed0
https://pubmed.ncbi.nlm.nih.gov/36479905

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Exercise-induced re-programming of age-related metabolic changes in microglia is accompanied by a reduction in senescent cells

Autor: Marina A. Lynch, Virginia Mela, Kingston H. G. Mills, Mark Milner, Bibiana C Mota, Áine M. Kelly, Aoife M. McGinley

Publikováno v: Brain, Behavior, and Immunity. 87:413-428

Microglial activation and neuroinflammatory changes are characteristic of the aged brain and contribute to age-related cognitive impairment. Exercise improves cognitive function in aged animals, perhaps because of a modulatory effect on microglial ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5f0c483a1b7ae1e0ccf34f38c45f95
https://doi.org/10.1016/j.bbi.2020.01.012

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Network Physiology in Aging and Frailty: The Grand Challenge of Physiological Reserve in Older Adults

Autor: Rose Galvin, Roman Romero-Ortuno, Andrea Ungar, Artur Fedorowski, Jurgen Claassen, Richard B. Reilly, Plamen Ch. Ivanov, Richard Sutton, Áine M Kelly, Andrew Davies, Olga Theou, Nicolás Martínez-Velilla

Publikováno v: Frontiers in Network Physiology. 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3414a53a2c81affdbac56eee26d16d56
https://doi.org/10.3389/fnetp.2021.712430

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An investigation into the relationship between cardiorespiratory fitness, cognition and BDNF in young healthy males

Autor: Jennifer Fortune, Áine M. Kelly, Ian H. Robertson, Juliette Hussey

Publikováno v: Neuroscience Letters. 704:126-132

Background: Recent investigations demonstrate that cardiorespiratory fitness may benefit brain health and plasticity with concurrent enhancements in cognitive performance; possibly via a brain-derived neurotrophic factor (BDNF)-regulated mechanism. W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef9714bbad8c03c4dd2e40995f599e2b
https://doi.org/10.1016/j.neulet.2019.03.012

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Exercise-Induced Modulation of Neuroinflammation in Models of Alzheimer’s Disease

Autor: Áine M. Kelly

Publikováno v: Brain Plasticity

Alzheimer's disease (AD), a progressive, neurodegenerative condition characterised by accumulation of toxic βeta-amyloid (Aβ) plaques, is one of the leading causes of dementia globally. The cognitive impairment that is a hallmark of AD may be cause

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::614588d9151ea5de88bc613a306e46e5
http://europepmc.org/articles/PMC6296260

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Exercise alters LPS-induced glial activation in the mouse brain

Autor: Bibiana C Mota, Áine M. Kelly

Publikováno v: Neuronal Signaling

Experimental and epidemiological evidence suggest that modifiable lifestyle factors, including physical exercise, can build structural and cognitive reserve in the brain, increasing resilience to injury and insult. Accordingly, exercise can reduce th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad486991692ba191f629d41f4d82a869
https://pubmed.ncbi.nlm.nih.gov/33304620

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Acute high-intensity aerobic exercise affects brain-derived neurotrophic factor in mild cognitive impairment: a randomised controlled study

Autor: Marcel G. M. Olde Rikkert, Emer Guinan, Brian A. Lawlor, Stefan Schneider, Bibiana C Mota, Áine M. Kelly, Cathal Walsh, Kate E. Devenney

Publikováno v: BMJ Open Sport — Exercise Medicine
BMJ Open Sport & Exercise Medicine, Vol 5, Iss 1 (2019)
BMJ Open Sport & Exercise Medicine, 5, e000499
BMJ Open Sport & Exercise Medicine, 5, 1, pp. e000499

ObjectiveTo investigate the brain-derived neurotrophic factor (BDNF) and cognitive response to a short bout of high-intensity aerobic exercise in older adults with mild cognitive impairment (MCI).MethodsParticipants were randomised to one of two test

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e2d4373d913b4bb5965e33d344ee36
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/208125

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