Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Águeda Martinez-Barriocanal"'
Autor:
Higinio Dopeso, Paulo Rodrigues, Fernando Cartón-García, Irati Macaya, Josipa Bilic, Estefanía Anguita, Li Jing, Bruno Brotons, Núria Vivancos, Laia Beà, Manuel Sánchez-Martín, Stefania Landolfi, Javier Hernandez-Losa, Santiago Ramon y Cajal, Rocío Nieto, María Vicario, Ricard Farre, Simo Schwartz, Jr., Sven C.D. van Ijzendoorn, Kazuto Kobayashi, Águeda Martinez-Barriocanal, Diego Arango
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109400- (2024)
Summary: Rho GTPases are molecular switches regulating multiple cellular processes. To investigate the role of RhoA in normal intestinal physiology, we used a conditional mouse model overexpressing a dominant negative RhoA mutant (RhoAT19N) in the in
Externí odkaz:
https://doaj.org/article/9d852163178f465ea052ec089ed5a27d
Autor:
John Winslow, Isabel T. Rubio, Johannes Sam, Vicente Peg, Violeta Serra, Ahmed Chenna, Pablo Umana, Cristina Saura, Paolo Nuciforo, Jeff Sperinde, Enrique J. Arenas, Rocio Vicario, Joaquín Arribas, Josep Tabernero, Weidong Huang, José Baselga, Santiago Escrivá-de-Romaní, Javier Cortes, Christian Klein, Sylvia Herter, Joan Seoane, Jitka Somandin, Roberta Fasani, Irene Rius Ruiz, Oliver Ast, Marta Escorihuela, Ismael Varela, Marina Bacac, Joan Albanell, Isabel Cuartas, Águeda Martinez Barriocanal, Beatriz Morancho, Anne Freimoser-Grundschober, Cristina Bernadó Morales, Antonio Luque, Maurizio Scaltriti
Publikováno v:
Science Translational Medicine. 10
T cell bispecific antibodies (TCBs) are engineered molecules that include, within a single entity, binding sites to the T cell receptor and to tumor-associated or tumor-specific antigens. The receptor tyrosine kinase HER2 is a tumor-associated antige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5afd191e7518caf55dcd9c937ab0adde
https://doi.org/10.1126/scitranslmed.aat1445
https://doi.org/10.1126/scitranslmed.aat1445
Autor:
Ana I. Matos, Carina Peres, Barbara Carreira, Liane I. F. Moura, Rita C. Acúrcio, Theresa Vogel, Erik Wegener, Filipa Ribeiro, Marta B. Afonso, Fábio M. F. Santos, Águeda Martínez‐Barriocanal, Diego Arango, Ana S. Viana, Pedro M. P. Góis, Liana C. Silva, Cecília M. P. Rodrigues, Luis Graca, Rainer Jordan, Ronit Satchi‐Fainaro, Helena F. Florindo
Publikováno v:
Advanced Science, Vol 10, Iss 25, Pp n/a-n/a (2023)
Abstract Immune checkpoint blockade reaches remarkable clinical responses. However, even in the most favorable cases, half of these patients do not benefit from these therapies in the long term. It is hypothesized that the activation of host immunity
Externí odkaz:
https://doaj.org/article/4b20ef243e294bf990270de291c0adb7
Autor:
Ismael Varela, Rocio Vicario, Johannes Sam, J. Baselga, Marina Bacac, Isabel T. Rubio, Jeff Sperinde, Cristina Saura, Jitka Somandin, Weidong Huang, Violeta Serra, Águeda Martinez Barriocanal, Maurizio Scaltriti, Beatriz Morancho, Antonio Luque, Oliver Ast, Ahmed Chenna, Irene Rius Ruiz, Christian Klein, Pablo Umana, John Winslow, Javier Cortes, Paolo Nuciforo, Sylvia Herter, Vicente Peg, Joaquín Arribas, Cristina Bernadó Morales, Anne Freimoser-Grundscholber, Josep Tabernero, Santiago Escrivá, Marta Escorihuela, Roberta Fasani
Publikováno v:
Cancer Research. 78:LB-292
T cell bispecific antibodies (TCBs) are engineered molecules that include, within a single entity, binding sites to the T cell receptor and to a tumor-specific or a tumor-associated antigen. The receptor tyrosine kinase HER2 is a tumor-associated ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a67b686fc1b2e2e61dadafb46139313
https://doi.org/10.1158/1538-7445.am2018-lb-292
https://doi.org/10.1158/1538-7445.am2018-lb-292
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Whole genome and transcriptome sequencing technologies have led to the identification of many long non-coding RNAs (lncRNAs) and stimulated the research of their role in health and disease. LncRNAs participate in the regulation of critical signaling
Externí odkaz:
https://doaj.org/article/62ca6857aa124574add80ad093a70520
Autor:
Rocio Vicario, Vicente Peg, Beatriz Morancho, Mariano Zacarias-Fluck, Junjie Zhang, Águeda Martínez-Barriocanal, Alexandra Navarro Jiménez, Claudia Aura, Octavio Burgues, Ana Lluch, Javier Cortés, Paolo Nuciforo, Isabel T Rubio, Elisabetta Marangoni, James Deeds, Markus Boehm, Robert Schlegel, Josep Tabernero, Rebecca Mosher, Joaquín Arribas
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129876 (2015)
A chromosomal region that includes the gene encoding HER2, a receptor tyrosine kinase (RTK), is amplified in 20% of breast cancers. Although these tumors tend to respond to drugs directed against HER2, they frequently become resistant and resume thei
Externí odkaz:
https://doaj.org/article/b8f0cd35f328483ca3ba72a0f0e5b491
Autor:
Aroa Ejarque-Ortiz, Carme Solà, Águeda Martínez-Barriocanal, Simó Schwartz, Margarita Martín, Hugo Peluffo, Joan Sayós
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123928 (2015)
CMRF35-like molecule-1 (CLM-1) belongs to a receptor family mainly expressed in myeloid cells that include activating and inhibitory receptors. CLM-1 contains two ITIMs and a single immunoreceptor tyrosine-based switch motif (ITSM), although also dis
Externí odkaz:
https://doaj.org/article/b0c46ce15376428381ca5b5ca77a6150