Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ágnes Welker"'
Autor:
Péter István Kulcsár, András Tálas, Zoltán Ligeti, Eszter Tóth, Zsófia Rakvács, Zsuzsa Bartos, Sarah Laura Krausz, Ágnes Welker, Vanessza Laura Végi, Krisztina Huszár, Ervin Welker
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Streptococcus pyogenes Cas9 (SpCas9) has been employed as a genome engineering tool with a promising potential within therapeutics. However, its off-target effects present major safety concerns for applications requiring high specificity. Ap
Externí odkaz:
https://doaj.org/article/5ea3c939ed4a4822bf4f4ba4073454b2
Publikováno v:
Cancers
Volume 13
Issue 1
Cancers, Vol 13, Iss 63, p 63 (2021)
Volume 13
Issue 1
Cancers, Vol 13, Iss 63, p 63 (2021)
Introduction: Squamous cell carcinomas (SCC) are a major subgroup of malignant tumors with a platinum-based first-line systematic chemotherapy. miRNAs play a role in various diseases and modulate therapy response as well. The aim of this study was to
Autor:
Krisztina Huszár, Zsombor Welker, András Tálas, Júlia Varga, Zoltan Gyorgypal, Ágnes Welker, Ervin Welker, Péter Ferenc Pach, E. Varga, Eszter Tóth, Gábor E. Tusnády, Gergely Erdős, Péter István Kulcsár
Publikováno v:
Nucleic Acids Research
Detailed target-selectivity information and experiment-based efficacy prediction tools are primarily available for Streptococcus pyogenes Cas9 (SpCas9). One obstacle to develop such tools is the rarity of accurate data. Here, we report a method terme