Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Ágnes Telbisz"'
Autor:
Orsolya Mózner, Boglárka Zámbó, Zsuzsa Bartos, Anna Gergely, Kata Sára Szabó, Bálint Jezsó, Ágnes Telbisz, György Várady, László Homolya, Tamás Hegedűs, Balázs Sarkadi
Publikováno v:
Membranes, Vol 13, Iss 10, p 822 (2023)
The human ABCG2 multidrug transporter plays a crucial role in the absorption and excretion of xeno- and endobiotics, contributes to cancer drug resistance and the development of gout. In this work, we have analyzed the effects of selected variants, r
Externí odkaz:
https://doaj.org/article/d2e751a0cf98473c95d382c7980d6546
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Transporters in the human liver play a major role in the clearance of endo- and xenobiotics. Apical (canalicular) transporters extrude compounds to the bile, while basolateral hepatocyte transporters promote the uptake of, or expel, various
Externí odkaz:
https://doaj.org/article/4ddf4cfaa6b9472a9a671a89aa7c8a37
Autor:
Ágnes Telbisz, Csilla Ambrus, Orsolya Mózner, Edit Szabó, György Várady, Éva Bakos, Balázs Sarkadi, Csilla Özvegy-Laczka
Publikováno v:
Pharmaceutics, Vol 13, Iss 1, p 81 (2021)
During the COVID-19 pandemic, several repurposed drugs have been proposed to alleviate the major health effects of the disease. These drugs are often applied with analgesics or non-steroid anti-inflammatory compounds, and co-morbid patients may also
Externí odkaz:
https://doaj.org/article/c73bd9faab8d4e24a621c1d9885c5d7f
Autor:
Edit Szabó, Dóra Türk, Ágnes Telbisz, Nóra Kucsma, Tamás Horváth, Gergely Szakács, László Homolya, Balázs Sarkadi, György Várady
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190629 (2018)
ABC multidrug transporters are key players in cancer multidrug resistance and in general xenobiotic elimination, thus their functional assays provide important tools for research and diagnostic applications. In this study we have examined the potenti
Externí odkaz:
https://doaj.org/article/9464bd06305d48278d5000f204f0913c
Autor:
Csilla Temesszentandrási-Ambrus, Szilárd Tóth, Rinkee Verma, Péter Bánhegyi, István Szabadkai, Ferenc Baska, Csaba Szántai-Kis, Ruben C Hartkoorn, Mary A Lingerfelt, Balázs Sarkadi, Gergely Szakács, László Őrfi, Valakunja Nagaraja, Sean Ekins, Ágnes Telbisz
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0202749 (2018)
Drug resistant tuberculosis (TB) is a major worldwide health problem. In addition to the bacterial mechanisms, human drug transporters limiting the cellular accumulation and the pharmacological disposition of drugs also influence the efficacy of trea
Externí odkaz:
https://doaj.org/article/1a845305b8a4467da0d15ebe921cc693
Autor:
Marija Mioč, Ágnes Telbisz, Katarina Radman, Branimir Bertoša, Tatjana Šumanovac, Balázs Sarkadi, Marijeta Kralj
Publikováno v:
Histochemistry and Cell Biology. 158:261-277
Overexpression of ABC transporters, such as ABCB1 and ABCG2, plays an important role in mediating multidrug resistance (MDR) in cancer. This feature is also attributed to a subpopulation of cancer stem cells (CSCs), having enhanced tumourigenic poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f3c2cd701d0d4c8e33183dd0254b443
https://doi.org/10.1007/s00418-022-02106-z
https://doi.org/10.1007/s00418-022-02106-z
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
Transporters in the human liver play a major role in the clearance of endo- and xenobiotics. Apical (canalicular) transporters extrude compounds to the bile, while basolateral hepatocyte transporters promote the uptake of, or expel, various compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4822c4bfd64bbe8a9a97573bfb4975c
https://doaj.org/article/4ddf4cfaa6b9472a9a671a89aa7c8a37
https://doaj.org/article/4ddf4cfaa6b9472a9a671a89aa7c8a37
Autor:
Tímea Bencsik, Balázs Zoltán Zsidó, Miklós Poór, Orsolya Ungvári, Katalin Kuffa, Éva Bakos, Violetta Mohos, Eszter Fliszár-Nyúl, Ágnes Telbisz, Csilla Özvegy-Laczka, Csaba Hetényi
Publikováno v:
Drug Metabolism and Disposition. 48:1064-1073
Chrysin is an abundant flavonoid in nature, and it is also contained by several dietary supplements. Chrysin is highly biotransformed in the body, during which conjugated metabolites chrysin-7-sulfate and chrysin-7-glucuronide are formed. These conju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db7d33728f82ef6a548e9e686d4306ac
https://doi.org/10.1124/dmd.120.000085
https://doi.org/10.1124/dmd.120.000085
Autor:
Zsuzsa Bartos, György Várady, György Török, László Homolya, Balázs Sarkadi, Orsolya Mózner, Boglárka Zámbó, Ágnes Telbisz, Tamás I. Orbán
Publikováno v:
Cellular and Molecular Life Sciences
The human ABCG2 multidrug transporter plays a crucial role in the absorption and excretion of xeno- and endobiotics; thus the relatively frequent polymorphic and mutant ABCG2 variants in the population may significantly alter disease conditions and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f57502e119723c3b3a2da04085d0e46
https://doi.org/10.1007/s00018-019-03186-2
https://doi.org/10.1007/s00018-019-03186-2
Transporters in the human liver play a major role in the metabolism of endo-and xenobiotics. Apical (canalicular) transporters extrude compounds to the bile, while basolateral hepatocyte transporters promote the uptake or expel various compounds into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::952cf2a19850f0b2899d8ad2871ed4c0
https://doi.org/10.21203/rs.3.rs-382702/v1
https://doi.org/10.21203/rs.3.rs-382702/v1
