Zobrazeno 1 - 10
of 46
pro vyhledávání: '"África González-Murillo"'
Autor:
Josune Zubicaray, Maria Ivanova, June Iriondo, Jorge García Martínez, Rafael Muñoz-Viana, Lorea Abad, Lorena García-García, Jesús González de Pablo, Eva Gálvez, Elena Sebastián, Manuel Ramírez, Luis Madero, Miguel Ángel Díaz, África González-Murillo, Julián Sevilla
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
IntroductionFanconi anemia (FA) is an inherited disorder characterized by bone marrow failure, congenital malformations, and predisposition to malignancies. Alterations in hematopoietic stem cells (HSC) have been reported, but little is known regardi
Externí odkaz:
https://doaj.org/article/a1912601287e4b89a684e68a105b628e
Autor:
Beatriz Martín-Antonio, Belén Blanco, África González-Murillo, Laura Hidalgo, Jordi Minguillón, Gema Pérez-Chacón, Next Generation CART MAD Consortium, Lucía Fernández, Halin Bareke, Andrés París-Muñoz, Adriana Mañas, Cristina Aguirre-Portolés, Alfonso Navarro-Zapata, Carmen Mestre-Durán, Marta Ibáñez-Navarro, Laura Clares-Villa, Sara Naharro, Antonio Perez-Martinez, Marcos Aldea, María Gaibar, Javier Ruiz-Navarro, Manuel Izquierdo, Juan M. Zapata, África González Murillo, Elena García Sánchez, Jorge García Martínez, Alba Rubio San Simón, Blanca Herrero, Gonzalo García Aguilera, Beatriz Horcajo Morera, Manuel Ramírez Orellana, Belén Blanco-Durango, Anais Jiménez-Reinoso, Rodrigo Lázaro-Gorines, Ivana Zagorac, Antonio Tapia Galisteo, Ángel Ramirez-Fernández, Laura Díez-Alonso, Carmen Dominguez-Alonso, Ainhoa Erce-Llamazares, Oana Hangiu, Laura Rubio Pérez, Marina Gómez Rosel, Alejandro Segura Tudela, Javier Arroyo-Ródena, Luis Álvarez-Vallina, Miguel Ángel Rodríguez Milla, Patricia García Rodríguez, Beatriz Somovilla Crespo, Javier García-Castro, Esperanza Esquinas Tarifa, Juana Serrano-López, Pilar Llamas-Sillero, Beatriz Martin-Antonio
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Adoptive T cellular immunotherapies have emerged as relevant approaches for treating cancer patients who have relapsed or become refractory (R/R) to traditional cancer treatments. Chimeric antigen receptor (CAR) T-cell therapy has improved survival i
Externí odkaz:
https://doaj.org/article/49d95b3c222f4b7389eb0625d73c49df
Autor:
Anaïs Jiménez-Reinoso, Magdalena Molero-Abraham, Cristina Cirauqui, Belén Blanco, Eva M. Garrido-Martin, Daniel Nehme-Álvarez, Carmen Domínguez-Alonso, Ángel Ramírez-Fernández, Laura Díez-Alonso, Ángel Nuñez-Buiza, África González-Murillo, Raquel Tobes, Eduardo Pareja, Manuel Ramírez-Orellana, José Luis Rodriguez-Peralto, Irene Ferrer, Jon Zugazagoitia, Luis Paz-Ares, Luis Álvarez-Vallina
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Adoptive transfer of tumor-infiltrating lymphocytes (TIL) has shown remarkable results in melanoma, but only modest clinical benefits in other cancers, even after TIL have been genetically modified to improve their tumor homing, cytotoxic potential o
Externí odkaz:
https://doaj.org/article/e8672f59553649e1a19d8ee020cd28b0
Autor:
Lorena García-García, Elena G. Sánchez, Mariya Ivanova, Keren Pastora, Cristina Alcántara-Sánchez, Jorge García-Martínez, Beatriz Martín-Antonio, Manuel Ramírez, África González-Murillo
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe clinical success of chimeric antigen receptor-modified T cells (CAR-T cells) for hematological malignancies has not been reproduced for solid tumors, partly due to the lack of cancer-type specific antigens. In this work, we used a nov
Externí odkaz:
https://doaj.org/article/ae61223ed1b840c18235788dbbc584d0
Autor:
Marta Isidro-Hernández, Ana Casado-García, Ninad Oak, Silvia Alemán-Arteaga, Belén Ruiz-Corzo, Jorge Martínez-Cano, Andrea Mayado, Elena G. Sánchez, Oscar Blanco, Ma Luisa Gaspar, Alberto Orfao, Diego Alonso-López, Javier De Las Rivas, Susana Riesco, Pablo Prieto-Matos, África González-Murillo, Francisco Javier García Criado, María Begoña García Cenador, Manuel Ramírez-Orellana, Belén de Andrés, Carolina Vicente-Dueñas, César Cobaleda, Kim E. Nichols, Isidro Sánchez-García
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The initial steps of B-cell acute lymphoblastic leukemia (B-ALL) development usually pass unnoticed in children. Several preclinical studies have shown that exposure to immune stressors triggers the transformation of preleukemic B cells to f
Externí odkaz:
https://doaj.org/article/7edbe4149620489b8ca43749dc557848
Autor:
Raquel González-Novo, Ana de Lope-Planelles, María Pilar Cruz Rodríguez, África González-Murillo, Elena Madrazo, David Acitores, Mario García de Lacoba, Manuel Ramírez, Javier Redondo-Muñoz
Publikováno v:
European Journal of Cell Biology, Vol 102, Iss 3, Pp 151343- (2023)
Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, and the infiltration of leukemic cells is critical for disease progression and relapse. Nuclear deformability plays a critical role in cancer cell invasion through confined space
Externí odkaz:
https://doaj.org/article/51c38b50b2bf4a0a9e249892f4f92e07
Autor:
María Vinaixa, Sandra Canelles, África González-Murillo, Vítor Ferreira, Diana Grajales, Santiago Guerra-Cantera, Ana Campillo-Calatayud, Manuel Ramírez-Orellana, Óscar Yanes, Laura M. Frago, Ángela M. Valverde, Vicente Barrios
Publikováno v:
Cells, Vol 10, Iss 8, p 2085 (2021)
Insulin receptor substrate (IRS) 2 is a key mediator of insulin signaling and IRS-2 knockout (IRS2−/−) mice are a preclinical model to study the development of diabetes, as they develop peripheral insulin resistance and beta-cell failure. The dif
Externí odkaz:
https://doaj.org/article/d46ff4296d1f473da67f9a2adc2ddc10
Autor:
Lidia Franco-Luzón, Sandra García-Mulero, Rebeca Sanz-Pamplona, Gustavo Melen, David Ruano, Álvaro Lassaletta, Luís Madero, África González-Murillo, Manuel Ramírez
Publikováno v:
Cancers, Vol 12, Iss 5, p 1104 (2020)
Little is known about the effect of oncolytic adenovirotherapy on pediatric tumors. Here we present the clinical case of a refractory neuroblastoma that responded positively to Celyvir (ICOVIR-5 oncolytic adenovirus delivered by autologous mesenchyma
Externí odkaz:
https://doaj.org/article/dd21158b7f1b489aa35f3e01a4858037
Autor:
Elena Madrazo, David Ruano, Lorea Abad, Estefanía Alonso-Gómez, Carmen Sánchez-Valdepeñas, África González-Murillo, Manuel Ramírez, Javier Redondo-Muñoz
Publikováno v:
Cancers, Vol 10, Iss 9, p 325 (2018)
Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. As ALL progresses, leukemic cells cross the endothelial barrier and infiltrate other tissues. Epigenetic enzymes represent novel therapeutic targets in hematological malignancies
Externí odkaz:
https://doaj.org/article/f0c723be68334f14bdcd84c270441e83
Autor:
Carmen Fiuza-Luces, África González-Murillo, Luisa Soares-Miranda, Jesús Martínez Palacio, Isabel Colmenero, Fernando Casco, Gustavo Melén, María Morán, Alejandro Lucia, Manuel Ramírez
Publikováno v:
Cell Transplantation, Vol 22 (2013)
Graft-versus-host-disease (GVHD) is a major complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT), which is associated with high morbimortality and decreased patients' physical capacity. We evaluated the effects of an 11-week
Externí odkaz:
https://doaj.org/article/b740031cc04a4c19b40867859283a7e0