Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Àngel Fenollar"'
Autor:
Marcell Crispim, Ignasi Bofill Verdaguer, Agustín Hernández, Thales Kronenberger, Àngel Fenollar, Lydia Fumiko Yamaguchi, María Pía Alberione, Miriam Ramirez, Sandra Souza de Oliveira, Alejandro Miguel Katzin, Luis Izquierdo
Publikováno v:
PLoS Pathogens, Vol 20, Iss 1, p e1011557 (2024)
A proposed treatment for malaria is a combination of fosmidomycin and clindamycin. Both compounds inhibit the methylerythritol 4-phosphate (MEP) pathway, the parasitic source of farnesyl and geranylgeranyl pyrophosphate (FPP and GGPP, respectively).
Externí odkaz:
https://doaj.org/article/237ca26c1906426da1acea6b60a8f15a
Autor:
Àngel Fenollar, Albert Ros-Lucas, María Pía Alberione, Nieves Martínez-Peinado, Miriam Ramírez, Miguel Ángel Rosales-Motos, Ling Y. Lee, Julio Alonso-Padilla, Luis Izquierdo
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 850-863 (2022)
The emergence of resistance to first-line antimalarials, including artemisinin, the last effective malaria therapy in some regions, stresses the urgent need to develop new effective treatments against this disease. The identification and validation o
Externí odkaz:
https://doaj.org/article/ed8b307435744cd396ba8358f429af7a
Autor:
Nieves Martinez-Peinado, Álvaro Lorente-Macías, Alejandro García-Salguero, Nuria Cortes-Serra, Ángel Fenollar-Collado, Albert Ros-Lucas, Joaquim Gascon, Maria-Jesus Pinazo, Ignacio J. Molina, Asier Unciti-Broceta, Juan J. Díaz-Mochón, María J. Pineda de las Infantas y Villatoro, Luis Izquierdo, Julio Alonso-Padilla
Publikováno v:
Pharmaceuticals, Vol 14, Iss 7, p 638 (2021)
Malaria and Chagas disease, caused by Plasmodium spp. and Trypanosoma cruzi parasites, remain important global health problems. Available treatments for those diseases present several limitations, such as lack of efficacy, toxic side effects, and dru
Externí odkaz:
https://doaj.org/article/2732b0160c824e21ba750a13df89f0ae