Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Àlex Robert-Moreno"'
Autor:
Àlex Robert-Moreno, Silvia Naranjo, Elisa de la Calle-Mustienes, José Luis Gómez-Skarmeta, Berta Alsina
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15907 (2010)
POU3F4 is a member of the POU-homedomain transcription factor family with a prominent role in inner ear development. Mutations in the human POU3F4 coding unit leads to X-linked deafness type 3 (DFN3), characterized by conductive hearing loss and prog
Externí odkaz:
https://doaj.org/article/ba2b51bd862c4bb492378cff64271950
Autor:
Àlex Robert-Moreno, Krysta Voesenek, Silvia Naranjo, José Luis Gómez-Skarmeta, Hannie Kremer, John Economides, Elisa de la Calle-Mustienes, Berta Alsina, Haris Kokotas, Maria Grigoriadou, Nele Hilgert, Guy Van Camp, Michael B. Petersen, Felipe Moreno
Publikováno v:
Human Genetics
Human Genetics, 128, 411-9
Human Genetics, 128, 4, pp. 411-9
Digital.CSIC. Repositorio Institucional del CSIC
instname
Recercat. Dipósit de la Recerca de Catalunya
Human genetics
Human Genetics, 128, 411-9
Human Genetics, 128, 4, pp. 411-9
Digital.CSIC. Repositorio Institucional del CSIC
instname
Recercat. Dipósit de la Recerca de Catalunya
Human genetics
9 páginas, 4 figuras.-- This article is distributed under the terms of the Creative Commons Attribution Noncommercial License.-- et al.
POU3F4 encodes a POU-domain transcription factor required for inner ear development. Defects in POU3F4 funct
POU3F4 encodes a POU-domain transcription factor required for inner ear development. Defects in POU3F4 funct
Autor:
Verónica Rodilla, M. Mar Albà, Vanessa Fernández-Majada, Lluis Espinosa, Alberto Villanueva, Mireia Duñach, Nuria Lopez-Bigas, Anna Bigas, Àlex Robert-Moreno, Xavier Sanjuan, Nicolás Bellora, Ferran Torres, Thomas Gridley, Sara González, Gabriel Capellá, Antonia Obrador-Hevia, Andrea Grilli
Publikováno v:
Proceedings of the National Academy of Sciences. 106:6315-6320
Notch has been linked to β-catenin-dependent tumorigenesis; however, the mechanisms leading to Notch activation and the contribution of the Notch pathway to colorectal cancer is not yet understood. By microarray analysis, we have identified a group
Publikováno v:
Molecular Biology of the Cell. 14:491-502
Notch and NFkappaB pathways are key regulators of numerous cellular events such as proliferation, differentiation, or apoptosis. In both pathways, association of effector proteins with nuclear corepressors is responsible for their negative regulation
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
Development-Cambridge
Development-Cambridge-, 2011, 138 (3), pp.397-408. ⟨10.1242/dev.056093⟩
instname
Development-Cambridge
Development-Cambridge-, 2011, 138 (3), pp.397-408. ⟨10.1242/dev.056093⟩
Proper spatial control of neurogenesis in the inner ear ensures the precise innervation of mechanotransducing cells and the propagation of auditory and equilibrium stimuli to the brain. Members of the Hairy and enhancer of split (Hes) gene family reg
Autor:
José Luis Gómez-Skarmeta, Elisa de la Calle-Mustienes, Berta Alsina, Silvia Naranjo, Àlex Robert-Moreno
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS ONE, Vol 5, Iss 12, p e15907 (2010)
PLoS ONE
Recercat. Dipósit de la Recerca de Catalunya
instname
PLoS ONE, Vol 5, Iss 12, p e15907 (2010)
PLoS ONE
Recercat. Dipósit de la Recerca de Catalunya
11 páginas, 7 figuras.-- This is an open-access article distributed under the terms of the Creative Commons Attribution License.
POU3F4 is a member of the POU-homedomain transcription factor family with a prominent role in inner ear development
POU3F4 is a member of the POU-homedomain transcription factor family with a prominent role in inner ear development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c5fe77310aa6647b929d85ea05218c9
http://hdl.handle.net/10261/40113
http://hdl.handle.net/10261/40113
Publikováno v:
The International journal of developmental biology. 54(6-7)
The main function of the Notch signaling pathway is to generate cell diversity during both embryonic development and adult tissue homeostasis. The extended use of this pathway, together with its conservation during evolution, is indicative of its imp
Autor:
Julia Inglés-Esteve, Jordi Guiu, Thomas Gridley, L. Riera, Àlex Robert-Moreno, Tariq Enver, Alex J. Tipping, Anna Bigas, Cristina Ruiz-Herguido, Elaine Dzierzak, Lluis Espinosa, M Eugenia López
Publikováno v:
EMBO Journal, 27(13), 1886-1895. Wiley-Blackwell
Specific deletion of Notch1 and RBPjkappa in the mouse results in abrogation of definitive haematopoiesis concomitant with the loss of arterial identity at embryonic stage. As prior arterial determination is likely to be required for the generation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42876101e2627fb77aebf7cd45069cbf
https://pure.eur.nl/en/publications/b2c91dd5-3c5a-4107-9f79-c7711b4163ee
https://pure.eur.nl/en/publications/b2c91dd5-3c5a-4107-9f79-c7711b4163ee
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
8 páginas.
Programmed cell death plays an important role in erythropoiesis under physiological and pathological conditions. In this study, we show that the Notch/RBPjkappa signaling pathway induces erythroid apoptosis in different hematopoietic
Programmed cell death plays an important role in erythropoiesis under physiological and pathological conditions. In this study, we show that the Notch/RBPjkappa signaling pathway induces erythroid apoptosis in different hematopoietic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b9d90a6c9169cea0d8b8fc4413c5af
http://hdl.handle.net/10261/41194
http://hdl.handle.net/10261/41194
Publikováno v:
Development (Cambridge, England). 132(5)
Definitive hematopoiesis in the mouse embryo originates from the aortic floor in the P-Sp/AGM region in close association with endothelial cells. An important role for Notch1 in the control of hematopoietic ontogeny has been recently established, alt