Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Àgatha Cabrero"'
Autor:
Mireia Jové, Joel Salla, Anna Planavila, Àgatha Cabrero, Liliane Michalik, Walter Wahli, Juan C. Laguna, Manuel Vázquez-Carrera
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 1, Pp 113-123 (2004)
Type 2 diabetes has been related to a decrease of mitochondrial DNA (mtDNA) content. In this study, we show increased expression of the peroxisome proliferator-activated receptor-α (PPARα) and its target genes involved in fatty acid metabolism in s
Externí odkaz:
https://doaj.org/article/b78e7176f6594d0ca2d32637ba580906
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 2, Pp 388-398 (2003)
Activation of nuclear factor-κB (NF-κB) is required for hypertrophic growth of cardiomyocytes. Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase I (CPT-I) that activates peroxisome proliferator-activated receptor α (PPARα) a
Externí odkaz:
https://doaj.org/article/181a12dee86c43af82fe64d310209ae0
Publikováno v:
Clínica e Investigación en Arteriosclerosis. 16:90-98
Fundamento Los receptores activados por proliferadores peroxisomicos (peroxisome proliferator-activated receptors [PPAR]) desempenan un papel fundamental en el control del metabolismo lipidico de los macrofagos. El objetivo del presente estudio ha si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04e0e2401d5ee2f1b7e0a0205ea0ee4f
https://doi.org/10.1016/s0214-9168(04)78969-x
https://doi.org/10.1016/s0214-9168(04)78969-x
Autor:
Juan C. Laguna, Anna Planavila, Walter Wahli, Joel Salla, Liliane Michalik, Àgatha Cabrero, Mireia Jové, Manuel Vázquez-Carrera
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 1, Pp 113-123 (2004)
Type 2 diabetes has been related to a decrease of mitochondrial DNA (mtDNA) content. In this study, we show increased expression of the peroxisome proliferator-activated receptor-α (PPARα) and its target genes involved in fatty acid metabolism in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9bc5c5a7db00f423654a682252504d4
http://www.sciencedirect.com/science/article/pii/S0022227520319271
http://www.sciencedirect.com/science/article/pii/S0022227520319271
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 2, Pp 388-398 (2003)
Activation of nuclear factor-kappaB (NF-kappaB) is required for hypertrophic growth of cardiomyocytes. Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase I (CPT-I) that activates peroxisome proliferator-activated receptor alpha (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3750460959901cced9defbe576ca992e
https://doi.org/10.1194/jlr.m200294-jlr200
https://doi.org/10.1194/jlr.m200294-jlr200
Autor:
Daniel Zambón, Núria Roglans, Àgatha Cabrero, Emilio Ros, Cristina Rodríguez, Juan C. Laguna, Ferran Novell, Antonia Bellido
Publikováno v:
Clinical Pharmacology & Therapeutics. 72:692-701
Background and Objectives Fibrates induce hepatic peroxisome proliferation and carcinogenesis in rodents by activating peroxisome proliferator-activated receptor α (PPARα). There is no conclusive evidence that humans are unresponsive to peroxisome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e9f185cb06ca49b29454c1749c593a2
https://doi.org/10.1067/mcp.2002.128605
https://doi.org/10.1067/mcp.2002.128605
Publikováno v:
Current Drug Target -Inflammation & Allergy. 1:243-248
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors which form a subfamily of the nuclear receptor gene family. This subfamily consists of three isotypes, alpha (NR1C1), gamma (NR1C3), and beta/delta (NRC1C2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab69ceabc168f84a0855bd382c0c2167
https://doi.org/10.2174/1568010023344616
https://doi.org/10.2174/1568010023344616
Autor:
Marta Alegret, Manuel Vázquez Carrera, Rosa M. Sánchez, Tomás Adzet, Àgatha Cabrero, Juan C. Laguna
Publikováno v:
Journal of Biological Chemistry. 277:10100-10107
Generation of reactive oxygen species may contribute to the pathogenesis of diseases involving intracellular lipid accumulation. To explore the mechanisms leading to these pathologies we tested the effects of etomoxir, an inhibitor of carnitine palmi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f534f92ab6391d79d35cadf2be75fb
https://doi.org/10.1074/jbc.m110321200
https://doi.org/10.1074/jbc.m110321200
Publikováno v:
Clínica e Investigación en Arteriosclerosis. 14:67-73
Fundamento Los valores elevados de leptina se asocian con un mayor riesgo cardiovascular en la obesidad a traves de un mecanismo desconocido. La isoforma gamma del receptor activado por proliferadores peroxisomicos (PPAR γ) desempena un papel fundam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f32acb17723e03df60da9326624c605
https://doi.org/10.1016/s0214-9168(02)78828-1
https://doi.org/10.1016/s0214-9168(02)78828-1
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1532:195-202
Uncoupling proteins (UCPs) are mitochondrial membrane proton transporters that uncouple respiration from oxidative phosphorylation by dissipating the proton gradient across the membrane. Treatment of C2C12 myotubes for 24 h with 40 microM etomoxir, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326244f6fa7a5695c8f15a1cb1c61f9b
https://doi.org/10.1016/s1388-1981(01)00131-7
https://doi.org/10.1016/s1388-1981(01)00131-7