Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Àfrica Marzal-Casacuberta"'
1
Akademický článek
ApoA-II expression in CETP transgenic mice increases VLDL production and impairs VLDL clearance
Autor: Joan Carles Escolà-Gil, Josep Julve, Àfrica Marzal-Casacuberta, Jordi Ordóñez-Llanos, Francesc González-Sastre, Francisco Blanco-Vaca
Publikováno v: Journal of Lipid Research, Vol 42, Iss 2, Pp 241-248 (2001)
Apolipoprotein (apo)A-II is a major high density lipoprotein (HDL) protein; however, its role in lipoprotein metabolism is largely unknown. Transgenic (Tg) mice that overexpress human apoA-II present functional lecithin: cholesterol acyltransferase d
Externí odkaz: https://doaj.org/article/7d9def12fe2b432db1ca2de1a3e9ec56
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2
Akademický článek
Expression of human apolipoprotein A-II in apolipoprotein E-deficient mice induces features of familial combined hyperlipidemia
Autor: Joan Carles Escolà-Gil, Josep Julve, Àfrica Marzal-Casacuberta, Jordi Ordóñez-Llanos, Francesc González-Sastre, Francisco Blanco-Vaca
Publikováno v: Journal of Lipid Research, Vol 41, Iss 8, Pp 1328-1338 (2000)
Familial combined hyperlipidemia (FCHL) is a common inherited hyperlipidemia and a major risk factor for atherothrombotic cardiovascular disease. The cause(s) leading to FCHL are largely unknown, but the existence of unidentified “major” genes th
Externí odkaz: https://doaj.org/article/fe8e436def6c49e5992ec893144c225c
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3
Akademický článek
Human apolipoprotein A-II is a pro-atherogenic molecule when it is expressed in transgenic mice at a level similar to that in humans: evidence of a potentially relevant species-specific interaction with diet
Autor: Joan Carles Escolà-Gil, Àfrica Marzal-Casacuberta, Josep Julve-Gil, Brian Y. Ishida, Jordi Ordóñez-Llanos, Lawrence Chan, Francesc González-Sastre, Francisco Blanco-Vaca
Publikováno v: Journal of Lipid Research, Vol 39, Iss 2, Pp 457-462 (1998)
We report on the effect of human apolipoprotein (apo) A-II transgene expression on atherosclerosis susceptibility in two transgenic lines (25.3 and 11.1) whose plasma human apoA-II concentrations (∼23 and 96 mg/dl, respectively) span the normal ran
Externí odkaz: https://doaj.org/article/f6c7bff98e3446819d9b9c2fd18aee03
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4
Expression of human apolipoprotein A-II in apolipoprotein E-deficient mice induces features of familial combined hyperlipidemia
Autor: Francesc González-Sastre, Francisco Blanco-Vaca, Jordi Ordóñez-Llanos, Josep Julve, Àfrica Marzal-Casacuberta, Joan Carles Escolà-Gil
Publikováno v: Journal of Lipid Research, Vol 41, Iss 8, Pp 1328-1338 (2000)
Europe PubMed Central
Familial combined hyperlipidemia (FCHL) is a common inherited hyperlipidemia and a major risk factor for atherothrombotic cardiovascular disease. The cause(s) leading to FCHL are largely unknown, but the existence of unidentified “major” genes th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8d229a9a3e63b5efca64ff2547078a
http://www.sciencedirect.com/science/article/pii/S0022227520334416
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5
Free cholesterol deposition in the cornea of human apolipoprotein A-II transgenic mice with functional lecithin: Cholesterol acyltransferase deficiency
Autor: Àfrica Marzal-Casacuberta, Elena Ruiz-Pérez, Ricardo P. Casaroli-Marano, Josep Julve-Gil, Francesc González-Sastre, Joan Carles Escolà-Gil, Francisco Blanco-Vaca
Publikováno v: Metabolism. 48:415-421
We have developed several lines of transgenic animals that overexpress different levels of human apolipoprotein A-II (apoA-II). The 11.1 transgenic line has human apoA-II in plasma at threefold the level in normolipidemic humans and a functional leci
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d987fe0a679bfce94fea5c91b87a831e
https://doi.org/10.1016/s0026-0495(99)90097-5
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6
Functional Lecithin:Cholesterol Acyltransferase Deficiency and High Density Lipoprotein Deficiency in Transgenic Mice Overexpressing Human Apolipoprotein A-II
Autor: Francisco Blanco-Vaca, Jianhe Shen, Santiago Calvet-Márquez, Josep Julve-Gil, Lawrence Chan, Àfrica Marzal-Casacuberta, Brian Y. Ishida, Francesc González-Sastre
Publikováno v: Journal of Biological Chemistry. 271:6720-6728
The concentration of high density lipoproteins (HDL) is inversely related to the risk of atherosclerosis. The two major protein components of HDL are apolipoprotein (apo) A-I and apoA-II. To study the role of apoA-II in lipoprotein metabolism and ath
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f078cffc02f4d2f26b0a9ce2efb24be9
https://doi.org/10.1074/jbc.271.12.6720
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7
Increased production of very-low-density lipoproteins in transgenic mice overexpressing human apolipoprotein A-II and fed with a high-fat diet
Autor: Josep Julve, Àfrica Marzal-Casacuberta, Francisco Blanco-Vaca, Joan Carles Escolà-Gil, Jordi Ordóñez-Llanos, Francesc González-Sastre
Publikováno v: Biochimica et biophysica acta. 1488(3)
We investigated the mechanisms that lead to combined hyperlipidemia in transgenic mice that overexpress human apolipoprotein (apo) A-II (line 11.1). The 11.1 transgenic mice develop pronounced hypertriglyceridemia, and a moderate increase in free fat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d41d6abdadb41c12331df55a026cf604
https://pubmed.ncbi.nlm.nih.gov/11082533
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8
ApoA-II expression in CETP transgenic mice increases VLDL production and impairs VLDL clearance
Autor: Jordi Ordóñez-Llanos, Francisco Blanco-Vaca, Francesc González-Sastre, Josep Julve, Joan Carles Escolà-Gil, Àfrica Marzal-Casacuberta
Publikováno v: Europe PubMed Central
Journal of Lipid Research, Vol 42, Iss 2, Pp 241-248 (2001)
Scopus-Elsevier
Apolipoprotein (apo)A-II is a major high density lipoprotein (HDL) protein; however, its role in lipoprotein metabolism is largely unknown. Transgenic (Tg) mice that overexpress human apoA-II present functional lecithin: cholesterol acyltransferase d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4120b528521777933ada4a0c441bda90
http://europepmc.org/abstract/med/11181754
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9
Molecular basis of fish-eye disease in a patient from Spain: Characterization of a novel mutation in the LCAT gene and lipid analysis of the cornea
Autor: Àfrica Marzal-Casacuberta, Xavier Pintó, Isabel Hurtado, Henry J. Pownall, Hui Zhen Fan, Francisco Blanco-Vaca, Concha Fiol, John J. Albers, Quein Pao, Tomás Martí, Shi Jing Qu, V. Gracia
Publikováno v: Scopus-Elsevier
Abstract The genetic and biochemical basis of fish-eye disease (FED) was investigated in a 63-year-old female proband with low plasma HDL cholesterol. Analyses of corneal and plasma lipids of the proband were consistent with impaired lecithin:cholest
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c69d5671109ff9e143674356d5f15816
http://www.scopus.com/inward/record.url?eid=2-s2.0-16944364616&partnerID=MN8TOARS
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10
Human apolipoprotein A-II is a pro-atherogenic molecule when it is expressed in transgenic mice at a level similar to that in humans: Evidence of a potentially relevant species-specific interaction with diet
Autor: Francesc González-Sastre, Francisco Blanco-Vaca, Lawrence Chan, Jordi Ordóñez-Llanos, Joan Carles Escolà-Gil, Brian Y. Ishida, Àfrica Marzal-Casacuberta, Josep Julve-Gil
Publikováno v: Universitat Autònoma de Barcelona
Journal of Lipid Research, Vol 39, Iss 2, Pp 457-462 (1998)
Scopus-Elsevier
Europe PubMed Central
We report on the effect of human apolipoprotein (apo) A-II transgene expression on atherosclerosis suscep- tibility in two transgenic lines (25.3 and 11.1) whose plasma human apoA-II concentrations ( , 23 and 96 mg/dl, re- spectively) span the normal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9dd6329d45b80f379e5623fc5725a98
https://portalrecerca.uab.cat/en/publications/51e6953f-4ec4-44e3-ba3b-de113a407661
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