Zobrazeno 1 - 10 of 704 pro vyhledávání: '"[SDV.SP.PG] Life Sciences [q-bio]/Pharmaceutical sciences/Galenic pharmacology"'
1
Tailoring PEGylated nanoparticle surface modulates inflammatory response in vascular endothelial cells
Autor: Soudeh F. Tehrani, Jean-Michel Rabanel, Samuel Legeay, Jérôme Cayon, Jérémie Riou, Patrick Saulnier, Sylvie Marleau, V. Gaëlle Roullin, Patrice Hildgen, Guillaume Bastiat
Publikováno v: European Journal of Pharmaceutics and Biopharmaceutics
European Journal of Pharmaceutics and Biopharmaceutics, In press, ⟨10.1016/j.ejpb.2022.04.003⟩
International audience; Polymer nanoparticles (NPs) are extensively studied as drug delivery systems for various therapeutic indications, including drug and imaging agent delivery to the brain. Despite intensive research, their toxicological profile
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dbe60222d509f64bee51213c0ee3773
https://doi.org/10.1016/j.ejpb.2022.04.003
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2
Defining Endocytic Pathways of Fucoidan-Coated PIBCA Nanoparticles from the Design of their Surface Architecture
Autor: M. C. B. Lira-Nogueira, V. P. Gibson, V. Nicolas, N. S. Santos-Magalhães, C. Vauthier
Publikováno v: Pharmaceutical Research
Pharmaceutical Research, In press, 2022 (Mar 1), pp.1-16. ⟨10.1007/s11095-022-03202-4⟩
International audience; PURPOSE: This work investigated the endocytic pathways taken by poly(isobutylcyanoacrylate) (PIBCA) nanoparticles differing in their surface composition and architecture, assuming that this might determine their efficiency of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f61f6884e672840c84033ae48770b8
https://doi.org/10.1007/s11095-022-03202-4
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3
Liquid crystalline lipid nanoparticles for combined delivery of curcumin, fish oil and BDNF: In vitro neuroprotective potential in a cellular model of tunicamycin-induced endoplasmic reticulum stress
Autor: Miora Rakotoarisoa, Borislav Angelov, Markus Drechsler, Valérie Nicolas, Thomas Bizien, Yulia E. Gorshkova, Yuru Deng, Angelina Angelova
Publikováno v: Smart Materials in Medicine
Smart Materials in Medicine, 2022, 3, pp.274-288. ⟨10.1016/j.smaim.2022.03.001⟩
International audience; We develop multidrug-loaded cubosome and spongosome lipid nanoparticles for targeting of endoplasmic reticulum stress as a potential emerging therapeutic strategy against neuronal degeneration. The multicompartment organizatio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de7bbc7f573e42c837ea7edf2c27e20b
https://doi.org/10.1016/j.smaim.2022.03.001
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4
Delivery Systems for Mitochondrial Gene Therapy: A Review
Autor: Diana Costa, Prisca Boisguerin, Ângela Sousa, Rúben Miguel Ribeiro Faria
Publikováno v: Pharmaceutics
Pharmaceutics, 2023, 15 (2), pp.572. ⟨10.3390/pharmaceutics15020572⟩
International audience; Mitochondria are membrane-bound cellular organelles of high relevance responsible for the chemical energy production used in most of the biochemical reactions of cells. Mitochondria have their own genome, the mitochondrial DNA
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e961c940820d55a20c81b0501901a31e
https://doi.org/10.3390/pharmaceutics15020572
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5
H2O2-Responsive Nanocarriers Prepared by RAFT-Mediated Polymerization-Induced Self-Assembly of N-(2-(Methylthio)ethyl)acrylamide for Biomedical Applications
Autor: Hien Phan, Robert Cavanagh, Damien Destouches, Francis Vacherot, Blandine Brissault, Vincenzo Taresco, Jacques Penelle, Benoit Couturaud
Publikováno v: ACS Applied Polymer Materials
ACS Applied Polymer Materials, 2022, 4 (10), pp.7778-7789. ⟨10.1021/acsapm.2c01327⟩
International audience; H2O2-sensitive block copolymer nanoparticles (NPs) composed of a hydrophilic macro-chain transfer agent (macro-CTA) and a hydrophobic thioether-bearing block were prepared by polymerization-induced self-assembly (PISA) approac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c07cb26b2d3c373bd9f3c780abf6674c
https://doi.org/10.1021/acsapm.2c01327
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6
Spheroplexes: Hybrid PLGA-cationic lipid nanoparticles, for in vitro and oral delivery of siRNA
Autor: Danielle Campiol Arruda, Anne-Marie Lachagès, Hélène Demory, Guillaume Escriou, René Lai-Kuen, Pierre-Yves Dugas, Céline Hoffmann, Stéphanie Bessoles, Guillaume Sarrabayrouse, Angelo Malachias, Stéphanie Finet, Pedro Lana Gastelois, Waldemar Augusto de Almeida Macedo, Armando da Silva Cunha, Pascal Bigey, Virginie Escriou
Publikováno v: Journal of Controlled Release
Journal of Controlled Release, 2022, 350, pp.228-243. ⟨10.1016/j.jconrel.2022.08.030⟩
International audience; Vectorized small interfering RNAs (siRNAs) are widely used to induce gene silencing. Among the delivery systems used, lipid-based particles are the most effective. Our objective was the development of novel lipid-polymer hybri
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4092a10928f4d39baa56cc395caea4d1
https://hal-cnrs.archives-ouvertes.fr/hal-03764331/document
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7
Effect of baobab pulp powder on controlled release properties of matrix tablet formulated with whey protein and alginate
Autor: Chervet, Arthur, Delanne, Améline, Garrait, Ghislain, FADHLAOUI, Khaled, Chalancon, Sandrine, Denis, Sylvain, Beyssac, Eric, Laine, Emmanuelle
Publikováno v: 4th European Conference on Pharmaceutics : Advanced technologies enabling new therapies
4th European Conference on Pharmaceutics : Advanced technologies enabling new therapies, Mar 2023, Marseille, France.
International audience
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2885::3a60e0d0021671168f6946d8ae90a954
https://hal.science/hal-04104108
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8
Amphiphilic phosphorous dendron micelles co-deliver microRNA inhibitor and doxorubicin for augmented triple negative breast cancer therapy
Autor: Liang Chen, Mengsi Zhan, Jin Li, Liu Cao, Huxiao Sun, Régis Laurent, Serge Mignani, Anne-Marie Caminade, Jean-Pierre Majoral, Xiangyang Shi
Publikováno v: Journal of materials chemistry‎ B
Journal of materials chemistry‎ B, 2023, 11 (24), pp.5483-5493. ⟨10.1039/D2TB02114E⟩
International audience; Combined chemo/gene therapy of cancer through different action mechanisms has been emerging to enhance the therapeutic efficacy towards cancer, and still remains a challenging task due to the lack of highly effective and bioco
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::400105af0d48f6c7a92885b8a1d5d884
https://hal.science/hal-04144460/document
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9
Single-Component Physical Hydrogels of Dendritic Molecules
Autor: Evgeny Apartsin, Anne-marie Caminade
Publikováno v: Journal of Composites Science
Journal of Composites Science, 2023, 7 (1), pp.26. ⟨10.3390/jcs7010026⟩
International audience; Hydrogels are hydrophilic, three-dimensional networks able to imprison large amounts of water and are largely used in pharmaceutical formulations. Hydrogels are frequently obtained from hydrophilic polymers, either natural, bi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddff9dbe60112328dee2499bd0a59bf3
https://hal.science/hal-03932728/document
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10
Solubility enhancement of mefenamic acid by inclusion complex with β-cyclodextrin: in silico modelling, formulation, characterisation, and in vitro studies
Autor: Ferhat Djerboua, Zineb Elbahri, Milad Baitiche, Dounia Sid, Zouhair Bouaziz, Mokhtar Boutahala, Marc Le Borgne
Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021, 36 (1), pp.605-617. ⟨10.1080/14756366.2020.1869225⟩
Journal of Enzyme Inhibition and Medicinal Chemistry, Informa Healthcare, 2021, 36 (1), pp.605-617. ⟨10.1080/14756366.2020.1869225⟩
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 605-617 (2021)
International audience; The aim of this study was to prepare and characterise inclusion complexes of a low water-soluble drug, mefenamic acid (MA), with b-cyclodextrin (b-CD). First, the phase solubility diagram of MA in b-CD was drawn from 0 to 21
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467038933b23bccf425af798601048df
https://doi.org/10.1080/14756366.2020.1869225
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