Zobrazeno 1 - 10
of 102
pro vyhledávání: '"[11C]PBR28"'
Akademický článek
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Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-6 (2020)
Abstract Background Lipopolysaccharide (LPS) is a classic immune stimulus. LPS combined with positron emission tomography (PET) 18 kDa translocator protein (TSPO) brain imaging provides a robust human laboratory model to study neuroimmune signaling.
Externí odkaz:
https://doaj.org/article/20129abec91f48a3b53181e745cc69b3
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
Granville J. Matheson, Pontus Plavén-Sigray, Anton Forsberg, Andrea Varrone, Lars Farde, Simon Cervenka
Publikováno v:
EJNMMI Research, Vol 7, Iss 1, Pp 1-6 (2017)
Abstract Purpose Kinetic modelling with metabolite-corrected arterial plasma is considered the gold standard for quantification of [11C]PBR28 binding to the translocator protein (TSPO), since there is no brain region devoid of TSPO that can serve as
Externí odkaz:
https://doaj.org/article/a7b5dc3081944cd7b695a346724dd527
Autor:
Katelyn M. Kozinski, Michael L. Himes, Brian J. Lopresti, Joseph R. Hibbeln, Matthew F. Muldoon, Rajesh Narendran, N. Scott Mason, Savannah Tollefson
Publikováno v:
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 7:998-1006
Docosahexaenoic acid (DHA) shows anti-inflammatory/proresolution effects in the brain. Higher red blood cell (RBC) DHA in humans is associated with improved cognitive performance and a lower risk for suicide. Here, we hypothesized that binding to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12056a723155b2e53933ec444bfddb64
https://doi.org/10.1016/j.bpsc.2021.09.005
https://doi.org/10.1016/j.bpsc.2021.09.005
Autor:
Merja Haaparanta-Solin, Juha O. Rinne, Olof Solin, Diana Bocancea, Jatta S. Helin, Francisco R. López-Picón, Semi Helin, Annelaure Damont, Frédéric Dollé, Thomas Keller, Anna Krzyczmonik
Publikováno v:
Molecular Imaging and Biology
Purpose In this study we compared the recently developed TSPO tracer [18F]F-DPA, with [18F]DPA-714 and [11C]PBR28 by performing in vivo PET imaging on the same Alzheimer’s disease mouse model APP/PS1-21 (TG) and wild-type (WT) mice with all three r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c120c5e40f6b17078ee94d90a381800d
http://europepmc.org/articles/PMC8760190
http://europepmc.org/articles/PMC8760190
Publikováno v:
Molecular Imaging and Biology. 24:404-415
To identify a reliable alternative to the full blood [11C]PBR28 quantification method that would be easily replicated in multiple research and clinical settings. Ten [11C]PBR28 scans were acquired from 7 healthy non-human primates (NHP). Arterial inp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e7b8857a474e94f6ee83433b9c8918d
https://doi.org/10.1007/s11307-021-01661-6
https://doi.org/10.1007/s11307-021-01661-6
Autor:
Tiago Reis Marques, David R. Owen, Oliver D. Howes, Mattia Veronese, Graham E. Searle, Eugenii A. Rabiner
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging
ObjectiveThe mitochondrial 18-kDa translocator protein (TSPO) is expressed by activated microglia and positron emission tomography enables the measurement of TSPO levels in the brain. Findings in schizophrenia have shown to vary depending on the outc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4025751002fca716e364cdb7ce55bc2f
https://doi.org/10.1007/s00259-021-05327-x
https://doi.org/10.1007/s00259-021-05327-x
Autor:
Jouni Tuisku, Aurelija Jucaite, Päivi Marjamäki, Jon Lampa, Jarkko Johansson, Laura L. Ekblad, Andrea Varrone, Pontus Plavén-Sigray, Anna Brück, Simon Cervenka, Ming-Kai Chen, Yiyun Huang, Christine M. Sandiego, Kelly P. Cosgrove, Lars Farde, K. Collste, Juha O. Rinne, Eva Kosek, Edward C. Gaiser, David Matuskey, Richard E. Carson, Semi Helin, Caroline Olgart Höglund, Mats Lekander, Irina Esterlis, Brian Pittman, Eero Rissanen, Laura Airas, Jean-Dominique Gallezot, Haidar Al-Abdulrasul, Christer Halldin, Noora Lindgren, Nabeel Nabulsi, Anton Forsberg, Ansel T. Hillmer, Per Stenkrona, Marcus Sucksdorff
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging
Purpose The purpose of this study was to investigate the effects of ageing, sex and body mass index (BMI) on translocator protein (TSPO) availability in healthy subjects using positron emission tomography (PET) and the radioligand [11C]PBR28. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86692ec96e0ef4e4b87748c6a904184a
https://doi.org/10.1007/s00259-019-04403-7
https://doi.org/10.1007/s00259-019-04403-7
Autor:
Julie K. Wisch, Jon Christensen, Anna H. Boerwinkle, Tammie L.S. Benzinger, Sarah A. Cooley, Robert H. Paul, Mandy D. Smith, Hussain Jafri, Yi Su, John Doyle, Beau M. Ances, Florin Vaida, Tricia H. Burdo, Jeremy F. Strain
Publikováno v:
J Acquir Immune Defic Syndr
Journal of acquired immune deficiency syndromes (1999), vol 85, iss 2
Journal of acquired immune deficiency syndromes (1999), vol 85, iss 2
OBJECTIVE: Despite combined antiretroviral therapy (cART), neuroinflammation may persist in persons living with HIV (PLWH) and contribute to cognitive impairment in this population. Positron emission tomography (PET) imaging targeting 18kDa transloca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf99e679c13599a3bf7f3162ab6b4637
https://doi.org/10.1097/qai.0000000000002435
https://doi.org/10.1097/qai.0000000000002435