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Population-based input function for TSPO quantification and kinetic modeling with [11C]-DPA-713

Autor: Sadek Nehmeh, Nicolas A. Karakatsanis, Claire Henchcliffe, Susan A. Gauthier, John W. Babich, Ashish Raj, Sneha Pandya, P. David Mozley, Anastasia Nikolopoulou, Sara A. Zein, Ajay Gupta, Mercy I. Akerele

Publikováno v: EJNMMI physics, vol 8, iss 1
EJNMMI Physics
EJNMMI Physics, Vol 8, Iss 1, Pp 1-17 (2021)

Introduction Quantitative positron emission tomography (PET) studies of neurodegenerative diseases typically require the measurement of arterial input functions (AIF), an invasive and risky procedure. This study aims to assess the reproducibility of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a355546187a40abf83108ed4fed1444
https://escholarship.org/uc/item/36x0c83c

Imaging glial activation in patients with post-treatment Lyme disease symptoms: a pilot study using [11C]DPA-713 PET

Autor: Tristan A. Reekie, Jennifer M. Coughlin, John N. Aucott, Martin G. Pomper, Kathleen T. Bechtold, William B. Mathews, Wojciech G. Lesniak, Alison W. Rebman, Ting Yang, Yong Du, Mark J. Soloski, Michael Kassiou, Robert F. Dannals, Sarah Frey, Erica A. Mihm, Erica S. Marshall, Hailey B. Rosenthal

Publikováno v: Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-7 (2018)

The pathophysiology of post-treatment Lyme disease syndrome (PTLDS) may be linked to overactive immunity including aberrant activity of the brain’s resident immune cells, microglia. Here we used [11C]DPA-713 and positron emission tomography to quan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d7b15481307b215ee32d89189c601a6
https://doi.org/10.1186/s12974-018-1381-4

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Imaging glial activation in patients with post-treatment Lyme disease symptoms: a pilot study using [ ¹¹ C]DPA-713 PET.

Autor: Coughlin JM; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Yang T; Division of Rheumatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Rebman AW; Division of Rheumatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Bechtold KT; Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Du Y; Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Mathews WB; Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Lesniak WG; Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Mihm EA; Division of Rheumatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Frey SM; Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Marshall ES; Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Rosenthal HB; Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Reekie TA; School of Chemistry, The University of Sydney, Sydney, NSW, 2006, Australia., Kassiou M; School of Chemistry, The University of Sydney, Sydney, NSW, 2006, Australia., Dannals RF; Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Soloski MJ; Division of Rheumatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Aucott JN; Division of Rheumatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. jaucott2@jhmi.edu.; Lutherville, USA. jaucott2@jhmi.edu., Pomper MG; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA. mpomper@jhmi.edu.; Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA. mpomper@jhmi.edu.; Baltimore, USA. mpomper@jhmi.edu.

Publikováno v: Journal of neuroinflammation [J Neuroinflammation] 2018 Dec 19; Vol. 15 (1), pp. 346. Date of Electronic Publication: 2018 Dec 19.