Zobrazeno 1 - 10
of 105
pro vyhledávání: '"[11C]-PK11195"'
Akademický článek
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Autor:
Ana Rita Silva, Patricia Regueira, André Peres, Ana Luísa Cardoso, Inês Baldeiras, Isabel Santana, Joaquim Cerejeira
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
IntroductionChronic neuroinflammatory events have been implicated in the pathophysiology of neurodegenerative conditions but no studies have directly examined the neuroinflammatory response to acute systemic infection in older people with dementia. T
Externí odkaz:
https://doaj.org/article/622dd625681f4ed9ae1da0b4a5b8b3b6
Autor:
Pontus Plavén-Sigray, Granville James Matheson, Zsolt Cselényi, Aurelija Jucaite, Lars Farde, Simon Cervenka
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Purpose The PET radioligand (R)-[11C]PK11195 is used to quantify the 18-kDa translocator protein (TSPO), a marker for glial activation. Since there is no brain region devoid of TSPO, an arterial input function (AIF) is ideally required for q
Externí odkaz:
https://doaj.org/article/14a6295bda984b289ae7eb4a4d2b7d5c
Autor:
Yo-Han Joo, Min-Woo Lee, Young-Don Son, Keun-A Chang, Maqsood Yaqub, Hang-Keun Kim, Paul Cumming, Jong-Hoon Kim
Publikováno v:
Biomedicines, Vol 10, Iss 1, p 34 (2021)
Adiponectin is an adipokine that mediates cellular cholesterol efflux and plays important roles in neuroinflammatory processes. In this study, we undertook positron emission tomography (PET) with the translocator protein (TSPO) ligand [11C]PK11195 an
Externí odkaz:
https://doaj.org/article/6d94b72561da4ffd8c7a1aa02e2d4a62
Introdução: Esclerose múltipla (EM) é uma doença desmielinizante e inflamatória do sistema nervoso central. Seu diagnóstico é clínico, auxiliado pela imagem de ressonância magnética, mas essa imagem não diferencia processos de inflamaçã
Akademický článek
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Autor:
Makoto Kitade, Hideaki Nakajima, Tetsuya Tsujikawa, Sakon Noriki, Tetsuya Mori, Yasushi Kiyono, Hidehiko Okazawa, Akihiko Matsumine
Publikováno v:
Journal of Clinical Medicine; Volume 12; Issue 1; Pages: 116
Activated microglia are involved in secondary injury after acute spinal cord injury (SCI) and in development of spinal cord-related neuropathic pain (NeP). The aim of the study was to assess expression of translocator protein 18 kDa (TSPO) as an indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::840685c5c9ed2a8e180f74711a831869
Autor:
Evan Reid, Tim D. Fryer, Antonina Kouli, Patrick Yu-Wai-Man, Roido Manavaki, Caroline H. Williams-Gray, Patrick F. Chinnery, Heather Biggs, Edward T. Bullmore, Zoe MacIntyre, Young T. Hong, Rita Horvath, Jelle van den Ameele, Franklin I. Aigbirhio
Publikováno v:
Neurology
article-version (Version of Record) 3
article-version (Version of Record) 3
ObjectiveTo explore the possibilities of radioligands against the mitochondrial outer membrane translocator protein (TSPO) as biomarkers for mitochondrial disease, we performed brain PET-MRI with [11C]PK11195 in 14 patients with genetically confirmed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::580191ddc541ac97f82e007d8ec533bd
https://doi.org/10.1212/wnl.0000000000012033
https://doi.org/10.1212/wnl.0000000000012033
Autor:
Fábio Marques, Aline Morais de Souza, Larissa Estessi de Souza, Caroline Cristiano Real, Carlos Alberto Buchpiguel, Daniele de Paula Faria, Milena Sales Pitombeira
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 12, Pp 2494-2498 (2021)
Neural Regeneration Research
Neural Regeneration Research
11C-PK11195 is a positron emitter tracer used for Positron Emission Tomography (PET) imaging of innate immune cell activation in studies of neuroinflammatory diseases. For the image quantitative analysis, it is necessary to quantify the intact fracti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ca8dab88127328771953d9d75a07d50
http://www.nrronline.org/article.asp?issn=1673-5374
http://www.nrronline.org/article.asp?issn=1673-5374
Akademický článek
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