Zobrazeno 1 - 3
of 3
pro vyhledávání: '"(R)-crizotinib"'
Autor:
François Potus, Steeve Provencher, Eve Tremblay, Roxane Paulin, Charifa Awada, Sébastien Bonnet, Olivier Boucherat
Publikováno v:
Circulation. 142
Introduction: Pulmonary arterial hypertension (PAH) is a vascular disease characterized by persistent elevation of pulmonary vascular resistance leading to right heart failure and death. In 10% of cases, PAH is induced by drugs including chemotherape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e90785b9d051cf081c26ad13af8cfc8
https://doi.org/10.1161/circ.142.suppl_3.15624
https://doi.org/10.1161/circ.142.suppl_3.15624
Autor:
Yann Grobs, Olivier Boucherat, Sandra Breuils-Bonnet, Steeve Provencher, François Potus, Charlotte Romanet, Charifa Awada, Sandra Martineau, Wen-Hui Wu, Eve Tremblay, Karima Habbout, Sébastien Bonnet, Roxane Paulin
Publikováno v:
The European respiratory journal. 57(5)
Pulmonary hypertension (PH) is a life-threatening disease of multiple etiologies. Regardless of the underlying cause, PH is characterised by vasoconstriction and progressive thickening of the pulmonary vessel wall all of which is initiated by the los
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28cc1914696b1b0309b67dba800cf4a4
https://pubmed.ncbi.nlm.nih.gov/33446610
https://pubmed.ncbi.nlm.nih.gov/33446610
Publikováno v:
Journal of chemical theory and computation. 12(2)
As one of the most successful anticancer drugs, crizotinib is found to be efficient in the suppression of MTH1, a new therapeutic target for RAS-dependent cancers. Deep analysis shows that stereospecificity is prevalent in the binding of crizotinib t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::540d092d23c4ab06f76d6fc06a52cedc
https://pubmed.ncbi.nlm.nih.gov/26764587
https://pubmed.ncbi.nlm.nih.gov/26764587