Deep Learning in current Neuroimaging: a multivariate approach with power and type I error control but arguable generalization ability

Autor: Jiménez-Mesa, Carmen, Ramírez, Javier, Suckling, John, Vöglein, Jonathan, Levin, Johannes, Górriz, Juan Manuel, ADNI, Alzheimer's Disease Neuroimaging Initiative, DIAN, Dominantly Inherited Alzheimer Network

Discriminative analysis in neuroimaging by means of deep/machine learning techniques is usually tested with validation techniques, whereas the associated statistical significance remains largely under-developed due to their computational complexity.

Externí odkaz: http://arxiv.org/abs/2103.16685

Comparing cortical signatures of atrophy between late-onset and autosomal dominant Alzheimer disease

Autor: Dincer, Aylin, Gordon, Brian A, Allegri, Ricardo, Ances, Beau M, Berman, Sarah B, Brickman, Adam M, Brooks, William S, Cash, David M, Chhatwal, Jasmeer P, Farlow, Martin R, la Fougère, Christian, Fox, Nick C, Hari-Raj, Amrita, Fulham, Michael J, Jack, Clifford R, Joseph-Mathurin, Nelly, Karch, Celeste M, Lee, Athene, Levin, Johannes, Masters, Colin L, McDade, Eric M, Oh, Hwamee, Perrin, Richard J, Keefe, Sarah J, Raji, Cyrus, Salloway, Stephen P, Schofield, Peter R, Su, Yi, Villemagne, Victor L, Wang, Qing, Weiner, Michael W, Xiong, Chengjie, Yakushev, Igor, Morris, John C, Flores, Shaney, Bateman, Randall J, L S Benzinger, Tammie, DIAN, Dominantly Inherited Alzheimer Network, McKay, Nicole S, Paulick, Angela M, Shady Lewis, Kristine E, Feldman, Rebecca L, Hornbeck, Russ C

Publikováno v: NeuroImage: Clinical 28, 102491-(2020). doi:10.1016/j.nicl.2020.102491
NeuroImage: Clinical, Vol 28, Iss, Pp 102491-(2020)
NeuroImage : Clinical

Highlights • Cortical signatures selective to AD could provide an early MRI biomarker. • Autosomal dominant Alzheimer disease (ADAD) may model an ideal AD signature. • ADAD and late-onset maps overlap in parietal cortex but contain unique featu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2137b8c6fb5949e67aad2cd45279f38e
https://pub.dzne.de/record/154742