Zobrazeno 1 - 10
of 101
pro vyhledávání: '"'t Hoen PAC"'
Autor:
den Dunnen JT, Hooiveld GJEJ, Pedotti P, 't Hoen PAC, van Iterson M, van Ommen GJB, Boer JM, Menezes RX
Publikováno v:
BMC Genomics, Vol 10, Iss 1, p 439 (2009)
Abstract Background With the increasing number of expression profiling technologies, researchers today are confronted with choosing the technology that has sufficient power with minimal sample size, in order to reduce cost and time. These depend on d
Externí odkaz:
https://doaj.org/article/7d9de50073d54c9c8538095e7b7f4a72
Publikováno v:
BMC Genomics, Vol 6, Iss 1, p 98 (2005)
Abstract Background Duchenne muscular dystrophy (DMD), caused by mutations in the dystrophin gene, is lethal. In contrast, dystrophin-deficient mdx mice recover due to effective regeneration of affected muscle tissue. To characterize the molecular pr
Externí odkaz:
https://doaj.org/article/b74e7f208dfa485ea0d130dfa193c7be
Autor:
Shvetsova, E, Sofronova, A, Monajemi, R, Gagalova, K, Draisma, HHM, White, SJ, Santen, GWE, Lopes, SMCDS, Heijmans, BT, Van Meurs, J, Jansen, R, Franke, L, Kielbasa, SM, Den Dunnen, JT, 't Hoen, PAC, Boomsma, DI, Pool, R, Van Dongen, J, Hottenga, JJ, Van Greevenbroek, MMJ, Da Stehouwer, C, Van der Kallen, CJH, Schalkwijk, CG, Wijmenga, C, Zhernakova, S, Tigchelaar, EF, Slagboom, PE, Beekman, M, Deelen, J, Van Heemst, D, Veldink, JH, Van den Berg, LH, Van Duijn, CM, Hofman, BA, Uitterlinden, AG, Jhamai, PM, Verbiest, M, Suchiman, HED, Verkerk, M, Van der Breggen, R, Van Rooij, J, Lakenberg, N, Mei, H, Bot, J, Zhernakova, DV, 't Hof, PV, Deelen, P, Nooren, I, Moed, M, Vermaat, M, Luijk, R, Bonder, MJ, Van Iterson, M, Van Dijk, F, Van Galen, M, Arindrarto, W, Swertz, MA, Van Zwet, EW, Isaacs, A, Francioli, LC, Menelaou, A, Pulit, SL, Palamara, PF, Elbers, CC, Neerincx, PB, Ye, K, Guryev, V, Kloosterman, WP, Abdellaoui, A, Van Leeuwen, EM, Van Oven, M, Li, M, Laros, JF, Karssen, LC, Kanterakis, A, Amin, N, Lameijer, EW, Kattenberg, M, Dijkstra, M, Byelas, H, Van Setten, J, Van Schaik, BD, Nijman, IJ, Renkens, I, Marschall, T, Schonhuth, A, Hehir-Kwa, JY, Handsaker, RE, Polak, P, Sohail, M, Vuzman, D, Hormozdiari, F, Van Enckevort, D, Koval, V, Moed, MH, Van der Velde, KJ, Rivadeneira, F, Estrada, K, Medina-Gomez, C, McCarroll, SA, De Craen, AJ, Suchiman, HE, Oostra, B, Willemsen, G, Platteel, M, Pitts, SJ, Potluri, S, Sundar, P, Cox, DR, Sunyaev, SR, Stoneking, M, De Knijff, P, Kayser, M, Li, Q, Li, Y, Du, Y, Chen, R, Cao, H, Li, N, Cao, S, Wang, J, Bovenberg, JA, Pe'er, I, Van Ommen, GJ, De Bakker, PI
Publikováno v:
European Journal of Human Genetics
European Journal of Human Genetics, 27(3), 455-465. Nature Publishing Group
European journal of human genetics, 27(3), 455-465. Nature Publishing Group
European Journal of Human Genetics, 27(3), 455-465
European Journal of Human Genetics, 27, 455-465
European Journal of Human Genetics, 27(3), 455. Nature Publishing Group
European Journal of Human Genetics, 27, 3, pp. 455-465
Shvetsova, E, 't Hoen, P A C, Boomsma, D I, Pool, R, van Dongen, J, Hottenga, J J, Willemsen, G & BIOS Consortium 2019, ' Skewed X-inactivation is common in the general female population ', European Journal of Human Genetics, vol. 27, no. 3, pp. 455-465 . https://doi.org/10.1038/s41431-018-0291-3
Shvetsova, E, Sofronova, A, Monajemi, R, Gagalova, K, Draisma, H H M, White, S J, Santen, G W E, Chuva de Sousa Lopes, S M, Heijmans, B T, van Meurs, J, Jansen, R, Franke, L, Kiełbasa, S M, den Dunnen, J T, ‘t Hoen, P A C & BIOS Consortium 2019, ' Skewed X-inactivation is common in the general female population ', European Journal of Human Genetics, vol. 27, no. 3, pp. 455-465 . https://doi.org/10.1038/s41431-018-0291-3
European Journal of Human Genetics, 27(3), 455-465. Nature Publishing Group
European journal of human genetics, 27(3), 455-465. Nature Publishing Group
European Journal of Human Genetics, 27(3), 455-465
European Journal of Human Genetics, 27, 455-465
European Journal of Human Genetics, 27(3), 455. Nature Publishing Group
European Journal of Human Genetics, 27, 3, pp. 455-465
Shvetsova, E, 't Hoen, P A C, Boomsma, D I, Pool, R, van Dongen, J, Hottenga, J J, Willemsen, G & BIOS Consortium 2019, ' Skewed X-inactivation is common in the general female population ', European Journal of Human Genetics, vol. 27, no. 3, pp. 455-465 . https://doi.org/10.1038/s41431-018-0291-3
Shvetsova, E, Sofronova, A, Monajemi, R, Gagalova, K, Draisma, H H M, White, S J, Santen, G W E, Chuva de Sousa Lopes, S M, Heijmans, B T, van Meurs, J, Jansen, R, Franke, L, Kiełbasa, S M, den Dunnen, J T, ‘t Hoen, P A C & BIOS Consortium 2019, ' Skewed X-inactivation is common in the general female population ', European Journal of Human Genetics, vol. 27, no. 3, pp. 455-465 . https://doi.org/10.1038/s41431-018-0291-3
X-inactivation is a well-established dosage compensation mechanism ensuring that X-chromosomal genes are expressed at comparable levels in males and females. Skewed X-inactivation is often explained by negative selection of one of the alleles. We dem
Autor:
Graaf, A, Claringbould, A, Rimbert, A, Heijmans, BT, 't Hoen, PAC, van Meurs, Joyce, Jansen, R, Franke, L, Westra, HJ, Li, Y, Wijmenga, C, Sanna, S
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), ⟨10.1038/s41467-020-18716-x⟩
Nature Communications, 11(1):4930. Nature Publishing Group UK
Nature communications
England
BIOS Consortium 2020, ' Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids ', Nature Communications, vol. 11, no. 1, 4930 . https://doi.org/10.1038/s41467-020-18716-x
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications, 11(1):4930. Nature Publishing Group
Nature Communications, Nature Publishing Group, 2020, 11 (1), ⟨10.1038/s41467-020-18716-x⟩
Nature Communications, 11(1):4930. Nature Publishing Group UK
Nature communications
England
BIOS Consortium 2020, ' Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids ', Nature Communications, vol. 11, no. 1, 4930 . https://doi.org/10.1038/s41467-020-18716-x
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications, 11(1):4930. Nature Publishing Group
Inference of causality between gene expression and complex traits using Mendelian randomization (MR) is confounded by pleiotropy and linkage disequilibrium (LD) of gene-expression quantitative trait loci (eQTL). Here, we propose an MR method, MR-link
Autor:
Richard, MA, Huan, T, Ligthart, S, Gondalia, R, Jhun, MA, Brody, JA, Irvin, MR, Marioni, R, Shen, J, Tsai, PC, Montasser, ME, Jia, Y, Syme, C, Salfati, EL, Boerwinkle, E, Guan, W, Mosley, TH, Bressler, J, Morrison, AC, Liu, C, Mendelson, MM, Uitterlinden, AG, van Meurs, JB, Heijmans, BT, ’t Hoen, PAC, van Meurs, J, Isaacs, A, Jansen, R, Franke, L, Boomsma, DI, Pool, R, van Dongen, J, Hottenga, JJ, van Greevenbroek, MMJ, Stehouwer, CDA, van der Kallen, CJH, Schalkwijk, CG, Wijmenga, C, Zhernakova, A, Tigchelaar, EF, Slagboom, PE, Beekman, M, Deelen, J, van Heemst, D, Veldink, JH, van den Berg, LH, van Duijn, CM, Hofman, A, Jhamai, PM, Verbiest, M, Suchiman, HED, Verkerk, M, van der Breggen, R, van Rooij, J, Lakenberg, N, Mei, H, van Iterson, M, van Galen, M, Bot, J, van ’t Hof, P, Deelen, P, Nooren, I, Moed, M, Vermaat, M, Zhernakova, DV, Luijk, R, Bonder, MJ, van Dijk, F, Arindrarto, W, Kielbasa, SM, Swertz, MA, van Zwet, EW, Franco, OH, Zhang, G, Li, Y, Stewart, JD, Bis, JC, Psaty, BM, Chen, YDI, Kardia, SLR, Zhao, W, Turner, ST, Absher, D, Aslibekyan, S, Starr, JM
Publikováno v:
Richard, MA; Huan, T; Ligthart, S; Gondalia, R; Jhun, MA; Brody, JA; et al.(2017). DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation. American Journal of Human Genetics, 101(6), 888-902. doi: 10.1016/j.ajhg.2017.09.028. UCLA: Retrieved from: http://www.escholarship.org/uc/item/3670s683
© 2017 American Society of Human Genetics Genome-wide association studies have identified hundreds of genetic variants associated with blood pressure (BP), but sequence variation accounts for a small fraction of the phenotypic variance. Epigenetic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::584b9d7681d402a6374a446e2760c33d
http://www.escholarship.org/uc/item/3670s683
http://www.escholarship.org/uc/item/3670s683
Background: Sparse Gaussian graphical models are popular for inferring biological networks, such as gene regulatory networks. In this paper, we investigate the consistency of these models across different data platforms, such as microarray and next g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______900::3cab3f5be6a0a436618d9fc4db4fe571
http://bura.brunel.ac.uk/handle/2438/12947
http://bura.brunel.ac.uk/handle/2438/12947
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