Zobrazeno 1 - 7
of 7
pro vyhledávání: '"'Viktoriya G. Stancheva"'
Autor:
Joshua Hutchings, Viktoriya G. Stancheva, Nick R. Brown, Alan C. M. Cheung, Elizabeth A. Miller, Giulia Zanetti
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Cytosolic coat proteins capture secretory cargo and sculpt membrane carriers for intracellular transport, such as COPII which mediates Endoplasmic Reticulum to Golgi trafficking of thousands of cargoes. Here authors visualise the complete, membrane-a
Externí odkaz:
https://doaj.org/article/5898464a97104058b571bede3a2948c3
Autor:
Tamara L. Hendrickson, J. Christopher Fromme, Sudeep Banjade, Kaixian Liu, Daniel J. Barrero, Jing Zhang, Aditya Krishnakumar, Zhi Zheng, Saket R. Bagde, Travis J. Ness, Caroline Kisker, Xiao-Han Li, Scott Keeney, Viktoriya G. Stancheva, Eric C. Greene, Dana Branzei, Sergey Ovchinnikov, David Baker, Jochen Kuper, Elizabeth A. Miller, Upasana Roy, Barnabas Szakal, Josep Rizo, Israel S. Fernández, Ivan Anishchenko, Ian R. Humphreys, Minkyung Baek, Sue Biggins, Jimin Pei, Qian Cong
Publikováno v:
Science
Protein-protein interactions play critical roles in biology, but the structures of many eukaryotic protein complexes are unknown, and there are likely many interactions not yet identified. We take advantage of advances in proteome-wide amino acid coe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a37aed18d09e7e5517aeadb3ec6ac6
https://europepmc.org/articles/PMC7612107/
https://europepmc.org/articles/PMC7612107/
Autor:
Viktoriya G. Stancheva, Giulia Zanetti, Xiao-Han Li, Natalia Gomez-Navarro, M. Madan Babu, Elizabeth A. Miller, Balaji Santhanam, Joshua Hutchings
Publikováno v:
Journal of Cell Biology
The Journal of Cell Biology
The Journal of Cell Biology
Using in vitro reconstitution assays and in vivo cellular phenotypes, Stancheva and colleagues dissect the protein interaction network that drives COPII coat assembly during vesicle formation from the endoplasmic reticulum, revealing the importance o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7789efa658af6dd9cde1c7a0abb0e7cc
https://eprints.bbk.ac.uk/id/eprint/40708/1/Combinatorial-multivalent-interactions-drive
https://eprints.bbk.ac.uk/id/eprint/40708/1/Combinatorial-multivalent-interactions-drive
Autor:
Nick R. Brown, Elizabeth A. Miller, Viktoriya G. Stancheva, Joshua Hutchings, Giulia Zanetti, Alan C. M. Cheung
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Hutchings, J, Stancheva, V G, Brown, N R, Cheung, A C M, Miller, E A & Zanetti, G 2021, ' Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network ', Nature Communications, vol. 12, no. 1, 2034 (2021) . https://doi.org/10.1038/s41467-021-22110-6
Nature Communications
Hutchings, J, Stancheva, V G, Brown, N R, Cheung, A C M, Miller, E A & Zanetti, G 2021, ' Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network ', Nature Communications, vol. 12, no. 1, 2034 (2021) . https://doi.org/10.1038/s41467-021-22110-6
COPII mediates Endoplasmic Reticulum to Golgi trafficking of thousands of cargoes. Five essential proteins assemble into a two-layer architecture, with the inner layer thought to regulate coat assembly and cargo recruitment, and the outer coat formin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec3ab7b07086f4042001c0102ca64de
https://doi.org/10.1101/2020.06.18.159608
https://doi.org/10.1101/2020.06.18.159608
Autor:
Viktoriya G. Stancheva, Balaji Santhanam, M. Madan Babu, Giulia Zanetti, Elizabeth A. Miller, Joshua Hutchings, Xiao-Han Li
Protein secretion is initiated at the endoplasmic reticulum by the COPII coat, which self-assembles to form vesicles. Here, we examine the mechanisms by which the outer scaffolding layer of the coat drives local assembly of a structure rigid enough t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75c21b76239bf7a904de444c8907f8c9
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Nature Communications
Nature Communications
Eukaryotic cells employ membrane-bound carriers to transport cargo between compartments in a process essential to cell functionality. Carriers are generated by coat complexes that couple cargo capture to membrane deformation. The COPII coat mediates