Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Melissa Damon"'
Publikováno v:
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Symptoms associated with acute pancreatitis can be debilitating, and treatment remains a challenge. This study aimed to investigate the efficacy of selectively inhibiting the soluble form of TNF (solTNF) using the biologic XPro159
Externí odkaz:
https://doaj.org/article/ecd3117c6d8240cd955d1dbecc73b8bf
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 22:1378-1390
Aims: To determine the efficacy of XPro1595 to improve pathophysiological and functional outcomes in a mouse model of traumatic brain injury (TBI). Background: Symptoms associated with TBI can be debilitating, and treatment without off-target side ef
Autor:
Udaiyappan Janakiraman, Katelyn Larson, Nancy Nixon-Lee, Melissa Damon, Andrew Biscardi, Elisa Hawkins, Laxmikant S. Deshpande, Kirsty J. Dixon
BACKGROUNDSystemic inflammation is a major contributor to poor brain pathology across many disease conditions. Specifically, the upregulation of the pro-inflammatory cytokine TNF in the hippocampus activates its receptor TNFR1, reducing AMPA receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cb7b75f18d72c19dcca0fab9c4a409c
https://doi.org/10.1101/2022.11.28.518204
https://doi.org/10.1101/2022.11.28.518204
Publikováno v:
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-10 (2021)
BMC Gastroenterology
BMC Gastroenterology
Background Symptoms associated with acute pancreatitis can be debilitating, and treatment remains a challenge. This study aimed to investigate the efficacy of selectively inhibiting the soluble form of TNF (solTNF) using the biologic XPro1595 in a mo
Treatment of acute pancreatitis remains a challenge, with therapy focused on supportive care and treatment of the inciting etiology. Individuals with pancreatitis may experience severe upper abdominal pain, although pain mechanisms in patients with p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53fce54796ccbbda7438b3cdfab41337
https://doi.org/10.21203/rs.3.rs-126759/v1
https://doi.org/10.21203/rs.3.rs-126759/v1