Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Charlotte Thibeault"'
Autor:
Morgan Essex, Belén Millet Pascual-Leone, Ulrike Löber, Mathias Kuhring, Bowen Zhang, Ulrike Brüning, Raphaela Fritsche-Guenther, Marta Krzanowski, Facundo Fiocca Vernengo, Sophia Brumhard, Ivo Röwekamp, Agata Anna Bielecka, Till Robin Lesker, Emanuel Wyler, Markus Landthaler, Andrej Mantei, Christian Meisel, Sandra Caesar, Charlotte Thibeault, Victor M. Corman, Lajos Marko, Norbert Suttorp, Till Strowig, Florian Kurth, Leif E. Sander, Yang Li, Jennifer A. Kirwan, Sofia K. Forslund, Bastian Opitz
Publikováno v:
npj Biofilms and Microbiomes, Vol 10, Iss 1, Pp 1-15 (2024)
Abstract The clinical course of COVID-19 is variable and often unpredictable. To test the hypothesis that disease progression and inflammatory responses associate with alterations in the microbiome and metabolome, we analyzed metagenome, metabolome,
Externí odkaz:
https://doaj.org/article/3800ac4d0de04e14b83d18bba159a41d
Autor:
Mikhail Lebedin, Christoph Ratswohl, Amar Garg, Marta Schips, Clara Vázquez García, Lisa Spatt, Charlotte Thibeault, Benedikt Obermayer, January Weiner, 3rd, Ilais Moreno Velásquez, Cathrin Gerhard, Paula Stubbemann, Leif-Gunnar Hanitsch, Tobias Pischon, Martin Witzenrath, Leif Erik Sander, Florian Kurth, Michael Meyer-Hermann, Kathrin de la Rosa
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109330- (2024)
Summary: Identifying immune modulators that impact neutralizing antibody responses against severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) is of great relevance. We postulated that high serum concentrations of soluble angiotensin-co
Externí odkaz:
https://doaj.org/article/7c9c5701df2748eb9bb1238451f24137
Autor:
Florian Kurth, Elisa T. Helbig, Lena J. Lippert, Charlotte Thibeault, Gianluca Barbone, Marius A. Eckart, Martin Kluge, Tobias Puengel, Münevver Demir, Robert Röhle, Theresa Keller, Christoph Ruwwe-Glösenkamp, Martin Witzenrath, Norbert Suttorp, Christof von Kalle, Leif E. Sander, Christoph Jochum, Frank Tacke
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 32, Iss , Pp 44-47 (2023)
Objectives: C-C-chemokine receptors (CCRs) are expressed on a variety of immune cells and play an important role in many immune processes, particularly leukocyte migration. Comprehensive preclinical research demonstrated CCR2/CCR5-dependent pathways
Externí odkaz:
https://doaj.org/article/fd42a83ee4e342fab6bcb02045e44124
Statistical biases due to anonymization evaluated in an open clinical dataset from COVID-19 patients
Autor:
Carolin E. M. Koll, Sina M. Hopff, Thierry Meurers, Chin Huang Lee, Mirjam Kohls, Christoph Stellbrink, Charlotte Thibeault, Lennart Reinke, Sarah Steinbrecher, Stefan Schreiber, Lazar Mitrov, Sandra Frank, Olga Miljukov, Johanna Erber, Johannes C. Hellmuth, Jens-Peter Reese, Fridolin Steinbeis, Thomas Bahmer, Marina Hagen, Patrick Meybohm, Stefan Hansch, István Vadász, Lilian Krist, Steffi Jiru-Hillmann, Fabian Prasser, Jörg Janne Vehreschild, NAPKON Study Group
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-15 (2022)
Abstract Anonymization has the potential to foster the sharing of medical data. State-of-the-art methods use mathematical models to modify data to reduce privacy risks. However, the degree of protection must be balanced against the impact on statisti
Externí odkaz:
https://doaj.org/article/28a3080393434801b72639368e05f863
Autor:
Charlotte Thibeault, Lara Bardtke, Kanika Vanshylla, Veronica di Cristanziano, Kirsten A. Eberhardt, Paula Stubbemann, David Hillus, Pinkus Tober-Lau, Parnika Mukherjee, Friederike Münn, Lena J. Lippert, Elisa T. Helbig, Tilman Lingscheid, Fridolin Steinbeis, Mirja Mittermaier, Martin Witzenrath, Thomas Zoller, Pa-COVID study group, Florian Klein, Leif E. Sander, Florian Kurth
Publikováno v:
JCI Insight, Vol 8, Iss 8 (2023)
BACKGROUND After its introduction as standard-of-care for severe COVID-19, dexamethasone has been administered to a large number of patients globally. Detailed knowledge of its impact on the cellular and humoral immune response to SARS-CoV-2 remains
Externí odkaz:
https://doaj.org/article/229b1b6d598e45c5912da9fc1d7b7970
Autor:
Tatjana Schwarz, Pinkus Tober-Lau, David Hillus, Elisa T. Helbig, Lena J. Lippert, Charlotte Thibeault, Willi Koch, Irmgard Landgraf, Janine Michel, Leon Bergfeld, Daniela Niemeyer, Barbara Mühlemann, Claudia Conrad, Chantip Dang-Heine, Stefanie Kasper, Friederike Münn, Kai Kappert, Andreas Nitsche, Rudolf Tauber, Sein Schmidt, Piotr Kopankiewicz, Harald Bias, Joachim Seybold, Christof von Kalle, Terry C. Jones, Norbert Suttorp, Christian Drosten, Leif Erik Sander, Victor M. Corman, Florian Kurth
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 8, Pp 2174-2178 (2021)
We detected delayed and reduced antibody and T-cell responses after BNT162b2 vaccination in 71 elderly persons (median age 81 years) compared with 123 healthcare workers (median age 34 years) in Germany. These data emphasize that nonpharmaceutical in
Externí odkaz:
https://doaj.org/article/af1f98e3745c4d0180f53051d86658b4
Autor:
Pinkus Tober-Lau, Tatjana Schwarz, David Hillus, Jana Spieckermann, Elisa T. Helbig, Lena J. Lippert, Charlotte Thibeault, Willi Koch, Leon Bergfeld, Daniela Niemeyer, Barbara Mühlemann, Claudia Conrad, Stefanie Kasper, Friederike Münn, Frank Kunitz, Terry C. Jones, Norbert Suttorp, Christian Drosten, Leif Erik Sander, Florian Kurth, Victor M. Corman
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 8, Pp 2169-2173 (2021)
One week after second vaccinations were administered, an outbreak of B.1.1.7 lineage severe acute respiratory syndrome coronavirus 2 infections occurred in a long-term care facility in Berlin, Germany, affecting 16/20 vaccinated and 4/4 unvaccinated
Externí odkaz:
https://doaj.org/article/689178e7809e49a2984a116167606378
Autor:
Richard Dannebaum, Phillip Suwalski, Hosseinali Asgharian, Gracie Du Zhipei, Hai Lin, January Weiner, 3rd, Manuel Holtgrewe, Charlotte Thibeault, Melina Müller, Xiaomin Wang, Zehra Karadeniz, Jacopo Saccomanno, Jan-Moritz Doehn, Ralf-Harto Hübner, Bernd Hinzmann, Anja Blüher, Sandra Siemann, Dilduz Telman, Norbert Suttorp, Martin Witzenrath, Stefan Hippenstiel, Carsten Skurk, Wolfgang Poller, Leif E Sander, Dieter Beule, Florian Kurth, Toumy Guettouche, Ulf Landmesser, Jan Berka, Khai Luong, Florian Rubelt, Bettina Heidecker
Publikováno v:
EClinicalMedicine, Vol 48, Iss , Pp 101438- (2022)
Summary: Background: Disease progression of subjects with coronavirus disease 2019 (COVID-19) varies dramatically. Understanding the various types of immune response to SARS-CoV-2 is critical for better clinical management of coronavirus outbreaks an
Externí odkaz:
https://doaj.org/article/ea43228ea981419387b84f56bd729389
Autor:
Vadim Demichev, Pinkus Tober-Lau, Tatiana Nazarenko, Oliver Lemke, Simran Kaur Aulakh, Harry J Whitwell, Annika Röhl, Anja Freiwald, Mirja Mittermaier, Lukasz Szyrwiel, Daniela Ludwig, Clara Correia-Melo, Lena J Lippert, Elisa T Helbig, Paula Stubbemann, Nadine Olk, Charlotte Thibeault, Nana-Maria Grüning, Oleg Blyuss, Spyros Vernardis, Matthew White, Christoph B Messner, Michael Joannidis, Thomas Sonnweber, Sebastian J Klein, Alex Pizzini, Yvonne Wohlfarter, Sabina Sahanic, Richard Hilbe, Benedikt Schaefer, Sonja Wagner, Felix Machleidt, Carmen Garcia, Christoph Ruwwe-Glösenkamp, Tilman Lingscheid, Laure Bosquillon de Jarcy, Miriam S Stegemann, Moritz Pfeiffer, Linda Jürgens, Sophy Denker, Daniel Zickler, Claudia Spies, Andreas Edel, Nils B Müller, Philipp Enghard, Aleksej Zelezniak, Rosa Bellmann-Weiler, Günter Weiss, Archie Campbell, Caroline Hayward, David J Porteous, Riccardo E Marioni, Alexander Uhrig, Heinz Zoller, Judith Löffler-Ragg, Markus A Keller, Ivan Tancevski, John F Timms, Alexey Zaikin, Stefan Hippenstiel, Michael Ramharter, Holger Müller-Redetzky, Martin Witzenrath, Norbert Suttorp, Kathryn Lilley, Michael Mülleder, Leif Erik Sander, PA-COVID-19 Study group, Florian Kurth, Markus Ralser
Publikováno v:
PLOS Digital Health, Vol 1, Iss 1, p e0000007 (2022)
Global healthcare systems are challenged by the COVID-19 pandemic. There is a need to optimize allocation of treatment and resources in intensive care, as clinically established risk assessments such as SOFA and APACHE II scores show only limited per
Externí odkaz:
https://doaj.org/article/8c7d05377e464ce084389ab5400bb7df
Autor:
Mikhail Lebedin, Clara Vázquez García, Lisa Spatt, Christoph Ratswohl, Charlotte Thibeault, Lennard Ostendorf, Tobias Alexander, Friedemann Paul, Leif Erik Sander, Florian Kurth, Kathrin de la Rosa
Publikováno v:
European Journal of Immunology. 53