Zobrazeno 101 - 110
of 203
pro vyhledávání: '"Zhongquan Qi"'
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 300:L930-L939
Streptococcus pyogenes of the M1 serotype can cause streptococcal toxic shock syndrome and acute lung injury. Statins exert beneficial effects in septic patients although the mechanisms remain elusive. This study examined effects of simvastatin on M1
Autor:
Yuanzheng Peng, Jibing Chen, Feng Wang, Henrik Ekberg, Shuo Xu, Xiaomin Wang, Helong Dai, Wei Shao, Zhongquan Qi, Junjie Xia, Yingying Lin
Publikováno v:
Transplant Immunology; 24(4), pp 195-202 (2011)
Background: Alloreactive memory T cells are a major obstacle to transplantation acceptance due to their capacity for accelerated rejection. Methods: C57BL/6 mice that had rejected BALB/c skin grafts 4 weeks earlier were used as recipients. The recipi
Publikováno v:
Journal of Leukocyte Biology. 89:735-742
Statins have been reported to exert anti-inflammatory actions and protect against septic organ dysfunction. Herein, we hypothesized that simvastatin may attenuate neutrophil activation and lung damage in abdominal sepsis. Male C57BL/6 mice were pretr
Autor:
Xiangpeng Kang, Jinchun Xing, Henrik Thorlacius, Helong Dai, Shuo Xu, Yuanzheng Peng, Zhongquan Qi, Junjie Xia, Feng Wang, Wei Shao, Jibing Chen
Publikováno v:
Scandinavian Journal of Immunology. 73:190-197
Memory cells are currently thought to be a major barrier to tolerance induction in transplantation. However, whether alloreactive memory cells resulting from a primary transplant have cross-reactivity in a second transplant is unclear. Here, we used
Autor:
Fuqiang Wang, Zhongquan Qi, Tianshu Lan, Y. L. Huang, Xiangpeng Kang, Jibing Chen, Junjie Xia, Xuejun Wang, Henrik Ekberg, Baiyi Xie, Y. Z. Wang
Publikováno v:
Scandinavian Journal of Immunology. 73:91-101
It is well known that adoptive transfer of donor-derived tolerogenic dendritic cells (DC) helps to reduce acute allograft rejection. However, this method cannot effectively prevent grafts from infiltration of inflammatory cells and fibrosis, and thus
Autor:
Yuanzheng Peng, Jibing Chen, Junjie Xia, Xiaomin Wang, F. Wang, Henrik Ekberg, Panpan Cheng, Zhongquan Qi
Publikováno v:
Xenotransplantation. 17:460-468
Wang F, Xia J, Chen J, Peng Y, Cheng P, Ekberg H, Wang X, Qi Z. Combination of antibodies inhibits accelerated rejection mediated by memory T cells in xenoantigen-primed mice. Xenotransplantation 2010; 17: 460-468. © 2010 John Wiley & Sons A/S. Abst
Autor:
Ruifu Yang, Z. Kou, Y. Yang, Y. Xin, Xin Wang, X. Yang, Wei Wang, Chenglong Li, H. Liu, L. Zeng, Zijian Wang, B. Cui, Yu Liu, Yefeng Qiu, H. Wang, T. Liu, S. Huang, Q. Zhang, Zhongquan Qi, G. Liu
Publikováno v:
Scandinavian Journal of Immunology. 72:425-433
The subunit vaccine SV1 (20 μg F1 + 10 μg rV270) has been identified as the optimal formulation in mice, which provided a good protection against plague in mice, guinea pigs and rabbits. To compare SV1 and SV2 (200 μg F1 + 100 μg rV270) with live
Publikováno v:
Transplantation Proceedings. 42:2777-2781
Background We sought to explore the effect of CD44 targeting on the tolerance to memory cell-mediated graft rejection. Methods We developed a cardiac transplantation model in nude mice and administered anti-CD44 monoclonal antibodies (mAbs) to these
Autor:
Bengt Axelsson, Ingela Fritzson, Jibing Chen, Junjie Xia, Marie Törngren, Henrik Ekberg, Zhongquan Qi
Publikováno v:
Transplant Immunology. 23:180-184
We investigated the immunosuppressive effects of the dihydroortate dehydrogenase (DHODH) inhibitor compounds ABR-222417 and ABR-224050 from Active Biotech (Sweden). We verified the inhibitory effects of these compounds on the proliferation of CD4(+)
Autor:
Yongzhi Wang, Baiyi Xie, Jibing Chen, Ruxin Huang, Feng Tian, Wei Shao, Tianshu Lan, Henrik Thorlacius, Junjie Xia, Zhongquan Qi
Publikováno v:
Transplant International. 23:1154-1163
Memory T cells are known to play a key role in prevention of allograft tolerance in alloantigen-primed mice. Here, we used an adoptively transferred memory T cell model and an alloantigen-primed model to evaluate the abilities of different combinatio