Zobrazeno 101 - 110
of 159
pro vyhledávání: '"Yuma Yamada"'
Autor:
Yuma, Yamada, Hideyoshi, Harashima
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1265
Genetic mutations and defects in mitochondrial DNA (mtDNA) are associated with certain types of mitochondrial dysfunction, ultimately resulting in the occurrence of a variety of human diseases. For an effective mitochondrial gene therapy, it will be
Publikováno v:
Global Pediatric Health, Vol 2 (2015)
Global Pediatric Health
Global Pediatric Health
Autor:
Yuma Yamada, Hideyoshi Harashima
Publikováno v:
Methods in Molecular Biology ISBN: 9781493922871
Genetic mutations and defects in mitochondrial DNA (mtDNA) are associated with certain types of mitochondrial dysfunction, ultimately resulting in the occurrence of a variety of human diseases. For an effective mitochondrial gene therapy, it will be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1516e7ca7b669ab76ca0b79b28bac389
https://doi.org/10.1007/978-1-4939-2288-8_10
https://doi.org/10.1007/978-1-4939-2288-8_10
Publikováno v:
Innovative Medicine ISBN: 9784431556503
Real-time imaging of the specific markers of lesions in the living body will provide valuable information in various physiopathological situations. Clinically, real-time imaging will definitely aid accurate diagnosis and rational therapy, especially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bc0db3c60f0e94eb6efff7a562ceaee
https://doi.org/10.1007/978-4-431-55651-0_22
https://doi.org/10.1007/978-4-431-55651-0_22
Publikováno v:
Journal of Pharmacy and Pharmacology. 58:431-437
A multifunctional envelope-type nano device (MEND) was developed for use as an efficient non-viral system for the delivery of plasmid DNA (pDNA) using octaarginine (R8) as an internalizing ligand. Three types of R8-MENDs were prepared, co-encapsulati
Publikováno v:
Biomaterials. 52
The cellular uptake pathway for a gene vector is an important factor in transgene expression. We previously constructed an original gene vector, multifunctional envelope-type nano device (MEND). The use of octaarginine (R8), a cell-penetrating peptid
Publikováno v:
Advances in genetics. 88
It is anticipated that nucleic acid medicines will be in widespread use in the future, since they have the potential to cure diseases based on molecular mechanisms at the level of gene expression. However, intelligent delivery systems are required to
Autor:
Shinji Chaki, Yasuo Shinohara, Hideyoshi Harashima, Tomoyuki Kakudo, Yuma Yamada, Shiroh Futaki, Hiroyuki Kamiya
Publikováno v:
International journal of pharmaceutics. 303(1-2):1-7
Mastoparan (MP), a potent facilitator of mitochondrial permeability transition (PT), could be used as an antitumor agent, if it were encapsulated in a tumor selective delivery system. We recently developed transferrin-modified liposomes (Tf-L) with a
Publikováno v:
International Journal of Pharmaceutics. 299:34-40
The production of an exogenous protein by the transfection of a plasmid DNA encoding the protein was kinetically analyzed, to determine the efficiency of the transfection. Cultured NIH3T3 or HeLa cells, and the luciferase protein were used as a model
Autor:
Hidetaka Akita, Tetsuya Suhara, Shigeki Sasaki, Kaori Inoue, Yoshio Nakamura, Hideyoshi Harashima, Yuma Yamada, Fumi Nagatsugi, Kentaro Kogure
Publikováno v:
Biological & Pharmaceutical Bulletin. 28(10):1939-1942
An efficient delivery system is required if antisense oligodeoxynucleotides (ODN) are to be utilized for gene therapy. We report herein on the development of a novel ODN delivery system, ODN-encapsulated nano particles (ODN-ENP) using an efficient an