Zobrazeno 31 - 40
of 571
pro vyhledávání: '"Youyi Zhang"'
Autor:
Xiaowei Ma, Yongnan Fu, Han Xiao, Yao Song, Ruifei Chen, Jing Shen, Xiangbo An, Qiang Shen, Zijian Li, Youyi Zhang
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129971 (2015)
Regular exercise can protect the heart against external stimuli, but the mechanism is not well understood. We determined the role of adenosine monophosphate-activated protein kinase (AMPK) in regulating swimming exercise-mediated cardiac protection a
Externí odkaz:
https://doaj.org/article/bcb448b892bb4a04947fb6821c23f40d
Autor:
Qian Li, Liujiao Bian, Xinfeng Zhao, Xiaokang Gao, Jianbin Zheng, Zijian Li, Youyi Zhang, Ru Jiang, Xiaohui Zheng
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94955 (2014)
A new oriented method using a diazonium salt reaction was developed for linking β2-adrenoceptor (β2-AR) on the surface of macroporous silica gel. Stationary phase containing the immobilised receptor was used to investigate the interaction between
Externí odkaz:
https://doaj.org/article/e8ef3be4cc1941469d233f78d7fd97ce
Publikováno v:
Mediators of Inflammation, Vol 2014 (2014)
Externí odkaz:
https://doaj.org/article/9f5ced1462aa4f12a3e05bb359e911f6
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e97788 (2014)
Progression of chronic obstructive pulmonary disease is associated with small airway obstruction by accumulation of inflammatory mucous exudates. However, the mechanism of mucin hypersecretion after exposure to cigarette smoke (CS) is still not clear
Externí odkaz:
https://doaj.org/article/ca00f0c98a4747f094bef031a3fd302b
Autor:
Xiaojian Wang, Jizheng Wang, Ming Su, Changxin Wang, Jingzhou Chen, Hu Wang, Lei Song, Yubao Zou, Lianfeng Zhang, Youyi Zhang, Rutai Hui
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58570 (2013)
PURPOSE: Protein kinase plays an essential role in controlling cardiac growth and hypertrophic remodeling. The cardiac troponin I-interacting kinase (TNNI3K), a novel cardiac specific kinase, is associated with cardiomyocyte hypertrophy. However, the
Externí odkaz:
https://doaj.org/article/92a7fb7a684c4c2b943b5ed34b9aa650
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67964 (2013)
Early identification for heart failure (HF) may be useful for disease modifying treatment in order to reduce heart disease progression or even to reverse it. In our previous studies, we have revealed a group of heat shock proteins (HSPs) which might
Externí odkaz:
https://doaj.org/article/cb4b7f4ca3df49cb8556ba3d7055d2ae
Autor:
Yao Song, Jialin Xu, Yanfeng Li, Chunshi Jia, Xiaowei Ma, Lei Zhang, Xiaojie Xie, Yong Zhang, Xiang Gao, Youyi Zhang, Dahai Zhu
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50436 (2012)
AimsIt has been reported that cardiac ankyrin repeat protein is associated with heart development and diseases. This study is aimed to investigate the role of CARP in heart hypertrophy in vivo.Methods and resultsWe generated a cardiac-specific CARP-o
Externí odkaz:
https://doaj.org/article/1f37027918784749a6e1a03c0d897066
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31201 (2012)
It has been reported that binding of STAT3 protein to the 5'-flanking region of the relaxin gene may result in downregulation of the relaxin expression. There is a Guanine(G)-rich segment located in about 3.8 Kb upstream of the relaxin gene and very
Externí odkaz:
https://doaj.org/article/91142f968cee4f988a7390e5228a5533
Autor:
Fei Liu, Kangmin He, Xinxing Yang, Ning Xu, Zhangyi Liang, Ming Xu, Xinsheng Zhao, Qide Han, Youyi Zhang
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21520 (2011)
G protein-coupled receptors (GPCRs) activate mitogen-activated protein kinases through a number of distinct pathways in cells. Increasing evidence has suggested that endosomal signaling has an important role in receptor signal transduction. Here we i
Externí odkaz:
https://doaj.org/article/32a46c57d8824fdeb0b93dc3199ec5ae
Autor:
Ming Xu, Peng Zhou, Shi-Ming Xu, Yin Liu, Xinheng Feng, Shu-Hua Bai, Yan Bai, Xue-Mei Hao, Qide Han, Youyi Zhang, Shi-Qiang Wang
Publikováno v:
PLoS Biology, Vol 5, Iss 2, p e21 (2007)
Pressure overload-induced hypertrophy is a key step leading to heart failure. The Ca(2+)-induced Ca(2+) release (CICR) process that governs cardiac contractility is defective in hypertrophy/heart failure, but the molecular mechanisms remain elusive.
Externí odkaz:
https://doaj.org/article/35ca7cafa33e4b63946bec55f5d574df