Zobrazeno 81 - 90
of 9 422
pro vyhledávání: '"Yong Xu"'
Autor:
Zhi Xu, Xiumei Wang, Wenbo Sun, Fan Xu, Hengyuan Kou, Weizi Hu, Yanyan Zhang, Qin Jiang, Jinhai Tang, Yong Xu
Publikováno v:
Redox Biology, Vol 68, Iss , Pp 102952- (2023)
Tamoxifen (TAM) resistance remains a major obstacle in the treatment of advanced breast cancer (BCa). In addition to the competitive inhibition of the estrogen receptor (ER) signaling pathway, damping of mitochondrial function by increasing reactive
Externí odkaz:
https://doaj.org/article/cda022a685ad4779829616c6c5140b48
Autor:
Guangtao Gao, Yong Xu, Jingjing Gan, Xinya Cao, Xiaoqing Dong, Mengkun Fang, Ying Du, Peipei Xu, Junyi Che, Bing Chen
Publikováno v:
APL Materials, Vol 11, Iss 12, Pp 121113-121113-10 (2023)
The discovery of bortezomib (BTZ) has been a major clinical breakthrough for multiple myeloma (MM) treatment. However, its clinical application is restricted to a low tumor-targeting ability, fast clearance, and treatment-related toxicity. Here, we r
Externí odkaz:
https://doaj.org/article/7c2a3db2dd3e4a8abc87fcd209093287
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Polyadenosine diphosphate-ribose polymerase (PARP) is a key modifying enzyme in cells, which participates in single-strand break repair and indirectly affects double-strand break repair. PARP inhibitors have shown great potential in oncotherapy by ex
Externí odkaz:
https://doaj.org/article/ead50660313f462ebf8a13980abfa520
Publikováno v:
Ecological Indicators, Vol 156, Iss , Pp 111170- (2023)
Over the past two decades (2000–2021), China has experienced a significant increase in vegetation cover. However, the intricate spatial and temporal variations in vegetation cover, arising from the interaction of climate change and human activities
Externí odkaz:
https://doaj.org/article/f5442052dd7f4edeae977d50fcf4162b
Autor:
Xiayu Hu, Xin Tian, Chunju Yang, Feng Ling, Hao Liu, Xuesong Zhu, Ming Pei, Huilin Yang, Tao Liu, Yong Xu, Fan He
Publikováno v:
Materials Today Bio, Vol 23, Iss , Pp 100811- (2023)
Intervertebral disc (IVD) herniation is a major cause of chronic low back pain and disability. The current nucleus pulposus (NP) discectomy effectively relieves pain symptoms, but the annulus fibrosus (AF) defects are left unrepaired. Tissue engineer
Externí odkaz:
https://doaj.org/article/1d1c49ffb20a4964a58a397bcb0670d6
Autor:
Kaijie Lin, Jingchi Qiao, Dongdong Gu, Haoran Wang, Bo Shi, Wanli Zhang, Junhao Shan, Yong Xu, Linhai Tian
Publikováno v:
Virtual and Physical Prototyping, Vol 18, Iss 1 (2023)
Laser powder bed fusion (LPBF) is capable to process complex flow field structures on 316L stainless steel (316L SS) bipolar plates, which is promising to improve the performance of proton exchange membrane fuel cell (PEMFC). However, insufficient co
Externí odkaz:
https://doaj.org/article/9a045cc3ba53486f9e5d416c7ad9e8d9
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-21 (2023)
Abstract Introduction There are countless possibilities for drug combinations, which makes it expensive and time-consuming to rely solely on clinical trials to determine the effects of each possible drug combination. In order to screen out the most e
Externí odkaz:
https://doaj.org/article/e1e0e54a634946189d19996dd7603d0d
Autor:
Xinzhe Du, Jinzhi Lv, Jianping Feng, Xinrong Li, Yao Gao, Xiao Wang, Wentao Zhao, Zhiyong Ren, Ruifang Zhang, Xiaohua Cao, Sha Liu, Yong Xu
Publikováno v:
BMC Psychiatry, Vol 23, Iss 1, Pp 1-16 (2023)
Abstract Background The exosomal lncRNA-miRNA-mRNA networks in first episode schizophrenia (FOS) have not reported yet. This study examined the lncRNA, miRNA and mRNA expression level in exosome derived from first episode schizophrenia (FOS) patients
Externí odkaz:
https://doaj.org/article/d16ce3ea987c464caec527e1cef35187
Autor:
Yong Xu, Xiaojuan Lu
Publikováno v:
Journal of Applied Science and Engineering, Vol 26, Iss 12, Pp 1859-1866 (2023)
The gas content in the oil is used as the fault input characteristic for the power transformer. Still, the accuracy of the diagnosis results is not ideal, and such a model is unstable. This research proposes a hybrid intelligent fault diagnosis metho
Externí odkaz:
https://doaj.org/article/0eb2d50dfa2b44618ecd420f4cea5340
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The prevalence of obesity is rapidly increasing worldwide, while the development of effective obesity therapies lags behind. Although new therapeutic targets to alleviate obesity are identified every day, and drug efficacy is improving, adve
Externí odkaz:
https://doaj.org/article/2c96b801a3f84459b9e80a5b9f593ca9