Zobrazeno 71 - 80
of 91
pro vyhledávání: '"Yazun Jarrar"'
Publikováno v:
The Libyan Journal of Medicine
Libyan Journal of Medicine, Vol 13, Iss 1 (2018)
Libyan Journal of Medicine; Vol 13, No 1 (2018)
Libyan Journal of Medicine, Vol 13, Iss 1 (2018)
Libyan Journal of Medicine; Vol 13, No 1 (2018)
The present study aimed to identify the NAT2 haplotypes, linkage disequilibrium, and novel NAT2 genetic variants among Jordanian population. We isolated the genomic DNA from 68 healthy, Arab, unrelated Jordanian volunteers to amplify the protein-codi
Publikováno v:
Drug Metabolism and Personalized Therapy. 32
BACKGROUND Human response to the antidiabetic metformin is influenced by some factors, such as genetic variants in the SLC22A genes. This study aimed to determine the frequency of main SLC22A1 and SLC22A3 genetic variants and their influence on metfo
Autor:
Sa'ed Zyoud, Yazun Jarrar
Publikováno v:
Journal of Applied Pharmaceutical Science.
Identification of cytochrome P450s involved in the metabolism of arachidonic acid in human platelets
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 89:227-234
Although cytochrome P450s (CYPs) have been identified in most human cells, identification of CYPs in human platelets remains poorly explored. CYP expressions in human platelets were screened by using reverse transcriptase-polymerase chain reaction an
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 51:593-599
Background: There are incon- sistent reports concerning N-acetyltransfer- ase 2 (NAT2) genotypes in diabetes mellitus (DM). Objective: The objective of the study was to explore any association between NAT2 genotypes and Type 1 and Type 2 DM in Jordan
Publikováno v:
In Vitro Cellular & Developmental Biology. Animal
Cytochrome P450s (P450s) are involved in the metabolism of arachidonic acid (ARA), and ARA metabolites are associated with various cellular signaling pathways, such as blood hemostasis and inflammation. The present study demonstrates the expression o
Publikováno v:
Drug Metabolism and Pharmacokinetics. 28:372-377
SULT1A1 and SULT1A2 are encoded on the same chromatid, and exhibit a 96% amino acid similarity. To screen for genetic variants in these two closely related genes, SULT1A1 and SULT1A2 were directly sequenced in 50 healthy Koreans. A total of 30 variat
Publikováno v:
Journal of Drug Metabolism & Toxicology.
The UDP-Glucuronesyl Transferase (UGT) 2B7*2 802C>T is the most common functional genetic variant on UGT2B7 gene with reported influence on drug response. Objective: To determine the frequency of UGT2B7*2 (802C>T) genetic variant among Jordanian popu
Publikováno v:
Platelets. 23:579-585
P2Y12 is an important G protein-coupled receptor that is involved in ADP-induced platelet aggregation, which is essential for normal haemostasis. Gender differences in the incidence of cardiovascular disease have been proposed to be linked to the eff
Publikováno v:
American Journal of Pharmacology and Toxicology. 7:19-26
Problem statement: Although the regulatory agencies of the United States and Europe banned hydroquinone in cosmetics skin lightening but it is still used in most of Middle East countries, including Saudi Arabia. Few studies were carried out on the hi