Zobrazeno 81 - 90
of 112
pro vyhledávání: '"Wungki Park"'
Autor:
Sarita Agte, Wungki Park, Naoyuki Okabe, A. Rahbari, Hiroyuki Suzuki, G. Lopes, Michael S. Oh, Deukwoo Kwon, Raja Mudad, Diana Saravia, Young Kwang Chae
Publikováno v:
Journal of Thoracic Oncology. 13:S696
Autor:
Ganji Purnachandra, Nagaraju, Purnachandra Nagaraju, Ganji, Wungki, Park, Jing, Wen, Hemchandra, Mahaseth, Jerome, Landry, Alton B, Farris, Field, Willingham, Patrick S, Sullivan, David A, Proia, Iman, El-Hariry, Latonia, Taliaferro-Smith, Roberto, Diaz, Bassel F, El-Rayes
Publikováno v:
Angiogenesis. 16:903-917
Hypoxia-inducible factors (HIFs) and STAT-3 play essential roles in angiogenesis. HIF-1α and STAT-3 are clients of the heat shock protein 90 (HSP90). We hypothesized that ganetespib, a potent HSP90 inhibitor, would disrupt angiogenesis in colorectal
Publikováno v:
Cellular Signalling. 25:1288-1300
Curcumin as an anticancer agent was investigated in regards to its ability to regulate the switching of cancer cells from survival to necrotic cell death. At higher concentrations, curcumin induced ROS production leading to JNK and p38 phosphorylatio
Autor:
Raja Mudad, Wungki Park
Publikováno v:
Journal of Thoracic Oncology. 12:S1247-S1248
Autor:
Lydia Koenig, Wungki Park, Daniel Rycroft, Yuxiang Wang, Dong M. Shin, Sujin Yun, Steve Holmes, Sreenivas Nannapaneni, Hyung Ju C. Shin, Michael Steward, Thil Batuwangala, Hongzheng Zhang, Mourad Tighiouart, Lin Pan, Zhuo Georgia Chen
Publikováno v:
International Journal of Cancer. 131:956-969
An antibody simultaneously targeting epidermal growth factor receptor (EGFR) and vascular endothelial growth factor (VEGF), two major tumor growth-driving machineries, may provide a novel effective strategy for optimizing tumor targeting and maximizi
Publikováno v:
Cancer Research. 78:701-701
Background: The dual roles of inflammation in malignancy has been well-described. Neutrophils play a key role in inflammation and carcinogenesis. We previously showed that high NLR may confer resistance to PD1/PDL1 inhibitors in lung cancer patients.
Autor:
Gilberto Lopes, Wungki Park, G. Azzam, Lorraine Portelance, Nagy Elsayyad, Eric A. Mellon, Arnold M. Markoe
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 101:E24
Autor:
Hiroyuki Suzuki, Raja Mudad, Diana Saravia, Amrita Desai, Laura Mezquita, Young Kwang Chae, Wungki Park, Gilberto Lopes, Benjamin Besse, Caroline Caramella, Naoyuki Okabe, Mohammad Jahanzeb, David Planchard, Deukwoo Kwon
Publikováno v:
Journal of Clinical Oncology. 36:3015-3015
3015Background: There is an unmet need for affordable and readily available biomarkers to predict outcomes to PD-1/PD-L1 inhibitors (PD-1/L1i) in advanced non-small cell lung cancer patients (aNSCL...
Autor:
Vaia Florou, Deukwoo Kwon, Darcy A. Kerr, Efrosyni Sfakianaki, Jonathan C. Trent, Andrew E. Rosenberg, Ty K. Subhawong, Despina Kolonias, Jaime R. Merchan, Wungki Park, Eric D. Wieder, Krishna V. Komanduri, Matteo Trucco, Breelyn A. Wilky
Publikováno v:
Journal of Clinical Oncology. 36:11547-11547
11547Background: Inhibition of programmed-death 1 (PD1) by pembrolizumab (P) produced overall response rates (ORR) of 19% in advanced STS [SARC028]. Vascular endothelial growth factor (VEGF) suppre...
Autor:
Raja Mudad, Laura Mezquita, Deukwoo Kwon, Young Kwang Chae, Benjamin Besse, Wungki Park, Gilberto Lopes, Naoyuki Okabe, Diana Saravia, Mohammad Jahanzeb, Hiroyuki Suzuki
Publikováno v:
Journal of Clinical Oncology. 36:e15102-e15102
e15102Background: PD-L1 expression is an imperfect predictor of outcomes for patients (pts) with advanced non-small cell lung cancer (aNSCLC) treated with PD-1/PD-L1 inhibitors (PD-1/L1i). Immunosu...