Zobrazeno 31 - 40
of 205
pro vyhledávání: '"Won-Ha Lee"'
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Vol 10 (2019)
The tumor necrosis factor (TNF) superfamily (TNFSF) is a protein superfamily of type II transmembrane proteins commonly containing the TNF homology domain. The superfamily contains more than 20 protein members, which can be released from the cell mem
Publikováno v:
Cell biology international. 43(3)
The functional and physical interaction between mitochondria and the endoplasmic reticulum (ER) has been the subject of intense study. To test the effect of this interaction on macrophage inflammatory activation, the human macrophage-like monocytic l
Publikováno v:
Current Alzheimer Research. 13:387-402
The central nervous system (CNS) shows dynamic immune and inflammatory responses to a variety of insults having crucial implications for reactive gliosis. Glial cells in the CNS serve not only as the source, but also as targets of proinflammatory med
Autor:
Habibur Rahman, Won-Ha Lee, Mithilesh Kumar Jha, Hyun Kook, Inkyu Lee, Dong Ho Park, Kyoungho Suk
Publikováno v:
Journal of Neuroscience Research. 94:837-849
Pyruvate dehydrogenase (PDH) kinases (PDKs) 1-4, expressed in peripheral and central tissues, regulate the activity of the PDH complex (PDC). The PDC is an important mitochondrial gatekeeping enzyme that controls cellular metabolism. The role of PDKs
Publikováno v:
Cellular Immunology. 296:115-121
MARCKS, a substrate of protein kinase C, is involved in various processes associated with cytoskeletal movement. Although the expression of MARCKS is highly induced in macrophages, its role in macrophage function has not been studied in detail. Notab
Autor:
Won-Ha Lee, Myungjin Jo, Quan Zhong, Marc Vidal, Jae-Hong Kim, Kyoungho Suk, Frederick P. Roth, Yeojin Seo, Hyejin Jeon, Nozomu Yachie
Publikováno v:
Cells, Vol 9, Iss 1156, p 1156 (2020)
Cells
Volume 9
Issue 5
Cells
Volume 9
Issue 5
Kinases are critical intracellular signaling proteins. To better understand kinase-mediated signal transduction, a large-scale human&ndash
yeast genetic interaction screen was performed. Among 597 human kinase genes tested, 28 displayed strong t
yeast genetic interaction screen was performed. Among 597 human kinase genes tested, 28 displayed strong t
Publikováno v:
Current proteinpeptide science. 19(7)
Spinal cord circuits play a key role in receiving and transmitting somatosensory information from the body and the brain. They also contribute to the timing and coordination of complex patterns of movement. Under disease conditions, such as spinal co
Publikováno v:
Animal Cells and Systems. 19:194-200
Bitter gourd is the fruit of a tropical vine in Asia, Africa, and South America where it is commonly used in traditional medicine. Our study tested the effects of a fermented extract of the bitter gourd on the inflammatory activities of the human mon
Autor:
Gyun Jee Song, Ho-Won Lee, Seong Soo A. An, Inkyu Lee, Kyoungho Suk, Jong Heon Kim, Won-Ha Lee, Mithilesh Kumar Jha, SangYun Kim
Publikováno v:
Progress in neurobiology. 162
Astrocytes, which are homeostatic cells of the central nervous system (CNS), display remarkable heterogeneity in their morphology and function. Besides their physical and metabolic support to neurons, astrocytes modulate the blood-brain barrier, regu
Autor:
Minchul Seo, Won Kee Lee, Youngheun Jee, Myungwon Jin, Youngpyo Nam, Sangmin Jeon, Jae-Hong Kim, Won-Ha Lee, So Jin Bing, Dong Ho Park, Kyoungho Suk, Jung Wan Seo, Jong Heon Kim, Hyun Kook
Publikováno v:
Journal of Biological Chemistry. 289:16773-16789
Lipocalin-2 (LCN2) plays an important role in cellular processes as diverse as cell growth, migration/invasion, differentiation, and death/survival. Furthermore, recent studies indicate that LCN2 expression and secretion by glial cells are induced by