Zobrazeno 11 - 20
of 457
pro vyhledávání: '"Williams, Brian G."'
Autor:
Williams, Brian G
The development of potent drugs for the control of viraemia in people living with HIV means that infected people may live a normal, healthy life and offers the prospect of eliminating HIV transmission in the short term and HIV infection in the long t
Externí odkaz:
http://arxiv.org/abs/1307.6045
Autor:
Williams, Brian G., Gouws, Eleanor
The Joint United Nations Programme on HIV and AIDS (UNAIDS) has set a new 90-90-90 global target for the coverage of anti-retroviral therapy (ART) to be reached by 2020. This would mean that 90% of all people infected with HIV know their status, 90%
Externí odkaz:
http://arxiv.org/abs/1304.3720
Anti-retroviral drugs can reduce the infectiousness of people living with HIV by about 96%--treatment as prevention or TasP--and can reduce the risk of being infected by an HIV positive person by about 70%--pre-exposure prophylaxis or PrEP--raising t
Externí odkaz:
http://arxiv.org/abs/1209.0364
In most countries CD4+ cell counts are still used for deciding when to start HIV-positive people on anti-retroviral therapy. However, various CD4+ thresholds, 200, 350 or 500/\muL, are chosen arbitrarily and for historical reasons. Here we consider t
Externí odkaz:
http://arxiv.org/abs/1208.3434
Autor:
Williams, Brian G., Gouws, Eleanor
If people at risk of HIV infection are tested annually and started on treatment as soon as they are found to be HIV-positive it should be possible to reduce the case reproduction number for HIV to less than one, eliminate transmission and end the epi
Externí odkaz:
http://arxiv.org/abs/1206.6774
In several countries in southern Africa, including South Africa, the prevalence of HIV remains stubbornly high in spite of considerable efforts to reduce transmission and to provide anti-retroviral therapy (ART). It is important to know the extent to
Externí odkaz:
http://arxiv.org/abs/1109.1170
Autor:
Williams, Brian G
The extent to which ART (anti-retroviral therapy) reduces HIV transmission has received attention in recent years. Using data on the relationship between transmission and viral load we show that transmission saturates at high viral loads. We fit a po
Externí odkaz:
http://arxiv.org/abs/1108.4715
Autor:
Williams, Brian G.
At present, the best hope for eliminating HIV transmission and bringing the epidemic of HIV to an end lies in the use of anti-retroviral therapy for prevention, a strategy referred to variously as Test and Treat (T&T), Treatment as Prevention (TasP)
Externí odkaz:
http://arxiv.org/abs/1105.2767
Autor:
Williams, Brian G., Dye, Christopher
In a study of the heterogeneity in malaria infection rates among children Smith et al.1 fitted several mathematical models to data from community studies in Africa. They concluded that 20% of children receive 80% of infections, that infections last a
Externí odkaz:
http://arxiv.org/abs/1105.2559
Autor:
Williams, Brian G.
We consider the optimal strategy for laboratory testing of biological samples when we wish to know the results for each sample rather than the average prevalence of positive samples. If the proportion of positive samples is low considerable resources
Externí odkaz:
http://arxiv.org/abs/1007.4903