Zobrazeno 11 - 20
of 256
pro vyhledávání: '"William N. William"'
Autor:
William N. William, Jianjun Zhang, Xin Zhao, Edwin R. Parra, Naohiro Uraoka, Heather Y. Lin, S. Andrew Peng, Adel K. El‐Naggar, Jaime Rodriguez‐Canales, Jaejoon Song, Ann M. Gillenwater, Ignacio I. Wistuba, Jeffrey N. Myers, Kathryn A. Gold, Renata Ferrarotto, Patrick Hwu, Teresa Davoli, J. Jack Lee, John V. Heymach, Vassiliki A. Papadimitrakopoulou, Scott M. Lippman
Publikováno v:
Cancer. 129:714-727
Studies of the immune landscape led to breakthrough trials of programmed death-1 (PD-1) inhibitors for recurrent/metastatic head and neck squamous cell carcinoma therapy. This study investigated the timing, influence of somatic copy-number alteration
Autor:
Rafael A Schmerling, Antonio C Buzaid, Carolina K Haddad, Fabio AB Schutz, Fabio R Kater, Juliana Pimenta, Fernando Maluf, William N William, Camila Lopes, Dafne R Bromberg, Ana C Oliveira, Ricardo Golmia, Morton Scheinberg
Publikováno v:
Future Science OA, Vol 7, Iss 1 (2021)
Objectives: The presence of autoimmune events were recorded in patients receiving immune checkpoint inhibitors. Materials & Methods: Retrospective study in patients receiving immune checkpoint inhibitors (ICIs) during the period of 2012–2019. Resul
Externí odkaz:
https://doaj.org/article/e47be0c0a15b444fb5acc44d1bd366ff
Autor:
Zhi-Yuan Zhang, Chen-Ping Zhang, J. Jack Lee, Jeffrey N. Myers, Jiang Li, Li-Zhen Wang, Xiao Yang, Cheng-Zhe Yang, Jie Ma, Ying Liu, William N. William, Dong-Wang Zhu, Lai-Ping Zhong
PDF file - 746K, Forest plot of overall survival, disease-free survival, locoregional recurrence-free survival, and distant metastasis-free survival in OSCC patients treated with surgery and post-operative radiotherapy with and without TPF induction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69fbccf3b982e8515829817ad5274847
https://doi.org/10.1158/1535-7163.22501264.v1
https://doi.org/10.1158/1535-7163.22501264.v1
Autor:
J. Silvio Gutkind, Robert L. Ferris, Raja R. Seethala, William N. William, Heather M. Walline, Christine M. Komarck, Jonathan B. McHugh, Thomas E. Carey, Nitin Gangane, Alfredo A. Molinolo, Abraham Schneider, Daniel Martin, Lynn Vitale-Cross, Dmitri Madera
Most squamous cell carcinomas of the head and neck (HNSCC) exhibit a persistent activation of the PI3K–mTOR signaling pathway. We have recently shown that metformin, an oral antidiabetic drug that is also used to treat lipodystrophy in HIV-infected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ebe021b3cd9c699280070cab44d3ccd
https://doi.org/10.1158/1940-6207.c.6544914.v1
https://doi.org/10.1158/1940-6207.c.6544914.v1
Autor:
John V. Heymach, William N. William, Diana Bell, Mark J. McArthur, Jeffrey N. Myers, Jing Wang, Xiangjun Tian, Don L. Gibbons, Limo N. Chen, Jared J. Fradette, Hampartsoum B. Barsoumian, Alissa Poteete, Marlese A. Pisegna, Monique Nilsson, Irene Guijarro, Taghreed Hirz, Jose A. Monteiro de Oliveira Novaes
We have previously demonstrated that PD-1 blockade decreased the incidence of high-grade dysplasia in a carcinogen-induced murine model of oral squamous cell carcinoma (OSCC). It remains unknown, however, whether there are additional factors involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80b501a7ce5502e03c3d3ea9f147e78f
https://doi.org/10.1158/1940-6207.c.6547574.v1
https://doi.org/10.1158/1940-6207.c.6547574.v1
Autor:
Zhi-Yuan Zhang, Chen-Ping Zhang, J. Jack Lee, Jeffrey N. Myers, Jiang Li, Li-Zhen Wang, Xiao Yang, Cheng-Zhe Yang, Jie Ma, Ying Liu, William N. William, Dong-Wang Zhu, Lai-Ping Zhong
PDF file - 81K, Supplemental table S1: Survival comparison between the cN2 patients treated with and without TPF induction chemotherapy. Supplemental table S2: Univariate Cox model analysis. Supplemental table S3: Multivariate Cox model analysis with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c31f5ad7dd83b31937d0031c631f912f
https://doi.org/10.1158/1535-7163.22501255.v1
https://doi.org/10.1158/1535-7163.22501255.v1
Autor:
Jianjun Zhang, Ignacio I. Wistuba, P. Andrew Futreal, James P. Allison, Padmanee Sharma, J. Jack Lee, Harlan Robins, John V. Heymach, Stephen Swisher, William N. William, Jennifer A. Wargo, Don L. Gibbons, Boris Sepesi, Chantale Bernatchez, Sharon Benzeno, Carmen Behrens, Cara Haymaker, Lorenzo Federico, Marie-Andrée Forget, Curtis Gumbs, Latasha D. Little, Edwin R. Parra, Jaime Rodriguez-Canales, Junya Fujimoto, Marissa Vignali, Tina Cascone, Luis M. Vence, Runzhe Chen, Vancheswaran Gopalakrishnan, Kelly Quek, Jun Li, Christopher Tipton, Jianhua Zhang, Ryan Emerson, Chang-Jiun Wu, Erik C. Yusko, Jiexin Zhang, Jianjun Gao, Rachel Gittelman, Alexandre Reuben
Supplemental Figure S1. Number of predicted neoantigens. Supplemental Figure S2. Association between expressed branch predicted neoantigens and relapse. Supplemental Figure S3. Substantial ITH in the number of unique T cell rearrangements. Supplement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949e59717c7cf38401c916522c9da2df
https://doi.org/10.1158/2159-8290.22532243
https://doi.org/10.1158/2159-8290.22532243
Autor:
Zhi-Yuan Zhang, Chen-Ping Zhang, J. Jack Lee, Jeffrey N. Myers, Jiang Li, Li-Zhen Wang, Xiao Yang, Cheng-Zhe Yang, Jie Ma, Ying Liu, William N. William, Dong-Wang Zhu, Lai-Ping Zhong
Induction chemotherapy is likely to be effective for biologically distinct subgroups of patients with cancer with biomarker detection. To investigate the prognostic and predictive values of cyclin D1 expression in patients with oral squamous cell car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::448f9ba2181ff68886385913a2e85069
https://doi.org/10.1158/1535-7163.c.6536725.v1
https://doi.org/10.1158/1535-7163.c.6536725.v1
Autor:
Zhi-Yuan Zhang, Chen-Ping Zhang, J. Jack Lee, Jeffrey N. Myers, Jiang Li, Li-Zhen Wang, Xiao Yang, Cheng-Zhe Yang, Jie Ma, Ying Liu, William N. William, Dong-Wang Zhu, Lai-Ping Zhong
PDF file - 3255K, Subgroup analysis of overall survival, disease-free survival, locoregional recurrence-free survival and distant metastasis free-survival in 232 OSCC patients with low and high cyclin D1 expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b725b5dec206adcaedc963e15c53fd3
https://doi.org/10.1158/1535-7163.22501258
https://doi.org/10.1158/1535-7163.22501258
Autor:
Pierre Saintigny, Li Mao, Scott M. Lippman, Jean-Pierre Issa, Jeffrey N. Myers, J. Jack Lee, Adel K. El-Naggar, Waun K. Hong, You H. Fan, Edward S. Kim, Li Zhang, Lei Feng, Wenhua Lang, Jing Wang, Mitchell J. Frederick, William N. William, Steven H. Lin, Jaroslav Jelinek, Vassiliki A. Papadimitrakopoulou, Curtis R. Pickering, Jean-Philippe Foy
DNA promoter methylation of tumor suppressor genes and global DNA hypomethylation are common features of head and neck cancers. Our goal was to identify early DNA methylation changes in oral premalignant lesions (OPL) that may serve as predictive mar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7129b6dc728d1379703dd57ccf22fa
https://doi.org/10.1158/1940-6207.c.6544334.v1
https://doi.org/10.1158/1940-6207.c.6544334.v1