Zobrazeno 21 - 30
of 528
pro vyhledávání: '"Vipul Jairath"'
Autor:
Bénédicte Caron, Vipul Jairath, Ferdinando D’Amico, Sameer Al Awadhi, Axel Dignass, Ailsa L. Hart, Taku Kobayashi, Paulo Gustavo Kotze, Fernando Magro, Britta Siegmund, Kristine Paridaens, Silvio Danese, Laurent Peyrin-Biroulet
Publikováno v:
Medicina, Vol 59, Iss 1, p 183 (2023)
Background and Objectives: At present, there is no consensus definition of mild-to-moderate disease activity in patients with ulcerative colitis. The objective of the present study was to establish a reliable definition of mild-to-moderate disease ac
Externí odkaz:
https://doaj.org/article/7084dc964d414d2a925b15b511cafcce
Publikováno v:
Rheumatology and Therapy, Vol 7, Iss 1, Pp 35-64 (2020)
Abstract The act of nonmedical switching, defined as switching stable patients who are generally doing well with their current therapy from an originator biologic to its biosimilar, has been endorsed as a reasonable treatment strategy. The safety and
Externí odkaz:
https://doaj.org/article/301392aadbb844ddac2bc06f48eea1f1
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 15, Iss 10, Pp 2482-2490 (2019)
Vedolizumab is a monoclonal antibody to the α4β7 integrin that selectively reduces intestinal lymphocyte trafficking, thereby providing a safe and effective treatment option for patients with inflammatory bowel disease (IBD). This product review ou
Externí odkaz:
https://doaj.org/article/5375fc85c13d434c820dccc6752b36d7
Autor:
Ian Roberts, Haleema Shakur-Still, Adefemi Afolabi, Adegboyega Akere, Monica Arribas, Emma Austin, Kiran Bal, Nuha Bazeer, Danielle Beaumont, Amy Brenner, Laura Carrington, Rizwana Chaudhri, Timothy Coats, Ian Gilmore, Kenneth Halligan, Irshad Hussain, Vipul Jairath, Kiran Javaid, Aasia Kayani, Ton Lisman, Raoul Mansukhani, Alec Miners, Muttiullah Mutti, Muhammad Arif Nadeem, Richard Pollok, Danielle Prowse, Jonathan Simmons, Simon Stanworth, Andrew Veitch, Jack Williams
Publikováno v:
Health Technology Assessment, Vol 25, Iss 58 (2021)
Background: Tranexamic acid reduces blood loss in surgery and the risk of death in trauma patients. Meta-analyses of small trials suggest that tranexamic acid decreases the number of deaths from gastrointestinal bleeding, but these meta-analyses are
Externí odkaz:
https://doaj.org/article/cbd5f7e4c4584e339cd0438d7a52635c
Autor:
Brian M. Yan, Michael S.L. Sey, Paul Belletrutti, Gary Brahm, Leonardo Guizzetti, Vipul Jairath
Publikováno v:
Endoscopy International Open, Vol 09, Iss 07, Pp E1116-E1122 (2021)
Background and study aims Endoscopic ultrasound (EUS) may be a useful modality for disease assessment and risk stratification in ulcerative colitis. We assessed the reliability of a newly developed EUS index of inflammation called the EUS-Ulcerative
Externí odkaz:
https://doaj.org/article/8abea38bdf9f4ba7ab9c8dbe92bdc1b1
Autor:
Amy Brenner, Adefemi Afolabi, Syed Masroor Ahmad, Monica Arribas, Rizwana Chaudhri, Timothy Coats, Jack Cuzick, Ian Gilmore, Christopher Hawkey, Vipul Jairath, Kiran Javaid, Aasia Kayani, Muttiullah Mutti, Muhammad Arif Nadeem, Haleema Shakur-Still, Simon Stanworth, Andrew Veitch, Ian Roberts, HALT-IT Trial Collaborators
Publikováno v:
Trials, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background Acute gastrointestinal (GI) bleeding is an important cause of mortality worldwide. Bleeding can occur from the upper or lower GI tract, with upper GI bleeding accounting for most cases. The main causes include peptic ulcer/erosive
Externí odkaz:
https://doaj.org/article/f6c14177ace24e6ab1752c6413de1d6a
Autor:
Stuart G. Nicholls, Kelly Carroll, Jamie Brehaut, Charles Weijer, Spencer Phillips Hey, Cory E. Goldstein, Merrick Zwarenstein, Ian D. Graham, Joanne E. McKenzie, Lauralyn McIntyre, Vipul Jairath, Marion K. Campbell, Jeremy M. Grimshaw, Dean A. Fergusson, Monica Taljaard
Publikováno v:
BMC Medical Ethics, Vol 19, Iss 1, Pp 1-10 (2018)
Abstract Background Randomized controlled trial (RCT) trial designs exist on an explanatory-pragmatic spectrum, depending on the degree to which a study aims to address a question of efficacy or effectiveness. As conceptualized by Schwartz and Lellou
Externí odkaz:
https://doaj.org/article/450a1be525dc4f398fff28e91bd66222
Autor:
Amy Brenner, Monica Arribas, Jack Cuzick, Vipul Jairath, Simon Stanworth, Katharine Ker, Haleema Shakur-Still, Ian Roberts
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-7 (2018)
Abstract Background Acute severe haemorrhage is a common complication of injury, childbirth, surgery, gastrointestinal pathologies and other medical conditions. Bleeding is a major cause of death, but patients also die from non-bleeding causes, the f
Externí odkaz:
https://doaj.org/article/7e3bb1f4817c40f7815cd2e62da22a82
Autor:
Monica Taljaard, Charles Weijer, Jeremy M. Grimshaw, Adnan Ali, Jamie C. Brehaut, Marion K. Campbell, Kelly Carroll, Sarah Edwards, Sandra Eldridge, Christopher B. Forrest, Bruno Giraudeau, Cory E. Goldstein, Ian D. Graham, Karla Hemming, Spencer Phillips Hey, Austin R. Horn, Vipul Jairath, Terry P. Klassen, Alex John London, Susan Marlin, John C. Marshall, Lauralyn McIntyre, Joanne E. McKenzie, Stuart G. Nicholls, P. Alison Paprica, Merrick Zwarenstein, Dean A. Fergusson
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-13 (2018)
Abstract Background There is a widely recognized need for more pragmatic trials that evaluate interventions in real-world settings to inform decision-making by patients, providers, and health system leaders. Increasing availability of electronic heal
Externí odkaz:
https://doaj.org/article/260cea66cc334647a8d886405fb83875
Autor:
Michael Sey, Brian Yan, Cassandra McDonald, Dan Segal, Joshua Friedland, Klajdi Puka, Vipul Jairath
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0249490 (2021)
BackgroundThe optimal dose of simethicone before capsule endoscopy is unknown. Prior studies have reported inconsistent cleansing, with some showing improved visualization only in the proximal small intestine. We hypothesized a higher volume of simet
Externí odkaz:
https://doaj.org/article/a01c83f6d2ad4eafb9f445a993abff23