Zobrazeno 21 - 30
of 73
pro vyhledávání: '"Veronica Vella"'
Autor:
Veronica Vella, Roberta Malaguarnera
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 12, p 3814 (2018)
Thyroid cancer (TC) is the most common endocrine tumor. Although the majority of TCs show good prognoses, a minor proportion are aggressive and refractory to conventional therapies. So far, the molecular mechanisms underlying TC pathogenesis are inco
Externí odkaz:
https://doaj.org/article/2df85112c5a341cd86b502a306fa86ca
Autor:
Veronica Vella, Rosamaria Lappano, Eduardo Bonavita, Marcello Maggiolini, Robert Bryan Clarke, Antonino Belfiore, Ernestina Marianna De Francesco
Publikováno v:
Endocrine Reviews.
In metabolic conditions such as obesity and diabetes, which are associated with deregulated signaling of the insulin/insulin-like growth factor system (IIGFs), inflammation plays a dominant role. In cancer, IIGFs is implicated in disease progression,
Autor:
Veronica Vella, Ernestina Marianna De Francesco, Eduardo Bonavita, Rosamaria Lappano, Antonino Belfiore
Publikováno v:
Trends in endocrinology and metabolism: TEM. 33(8)
Type I interferons (IFN-Is) are prototypical inflammatory cytokines produced in response to stress. IFN-Is have a critical role in antitumor immunity by driving the activation of leukocytes and favoring the elimination of malignant cells. However, IF
Autor:
Roberta Malaguarnera, Caterina Gabriele, Gianluca Santamaria, Marika Giuliano, Veronica Vella, Michele Massimino, Paolo Vigneri, Giovanni Cuda, Marco Gaspari, Antonino Belfiore
Publikováno v:
Molecular and cellular endocrinology. 557
The insulin receptor (IR) gene undergoes differential splicing generating two IR isoforms, IR-A and IR-B. The roles of IR-A in cancer and of IR-B in metabolic regulation are well known but the molecular mechanisms responsible for their different biol
Autor:
Ernestina Marianna De Francesco, Francesca Cirillo, Veronica Vella, Antonino Belfiore, Marcello Maggiolini, Rosamaria Lappano
Triple-negative breast cancer (TNBC) is a heterogeneous disease characterized by the lack of estrogen receptor (ER), progesterone receptor (PR), and epidermal growth factor receptor 2 (HER2) and often associated with poor survival outcomes. The backb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd4388a8da585a712fda7c5c1d7a0109
https://hdl.handle.net/20.500.11769/541369
https://hdl.handle.net/20.500.11769/541369
Autor:
Andrea Morrione, Maria Grazia Muoio, Veronica Vella, Ernestina Marianna De Francesco, Maria Luisa Nicolosi, Maria Giovanna Majorana, Marcello Maggiolini, Antonino Belfiore, Rosamaria Lappano, Marika Giuliano, Małgorzata Anna Marć
Publikováno v:
Biomolecules, Vol 11, Iss 926, p 926 (2021)
Biomolecules
Volume 11
Issue 7
Biomolecules
Volume 11
Issue 7
The insulin receptor isoform A (IR-A), a dual receptor for insulin and IGF2, plays a role in breast cancer (BC) progression and metabolic reprogramming. Notably, discoidin domain receptor 1 (DDR1), a collagen receptor often dysregulated in cancer, is
Autor:
Lucia Frittitta, Andrea Tumminia, Agostino Milluzzo, Veronica Vella, Laura Sciacca, Riccardo Vigneri, Fiorenza Gianì, Antonino Belfiore, Livia Manzella
Publikováno v:
Journal of Chemotherapy. 31:150-159
The short-term adverse effects of anticancer drugs (AD) in patients with type 2 diabetes (T2D) are poorly studied and their management still represents an important challenge for clinicians. We carried out a retrospective single-center study in 168 p
Autor:
Michele Massimino, Laura Sciacca, Adriana Puma, Veronica Vella, Elena Tirrò, Livia Manzella, Maria Stella Pennisi, Chiara Romano, Stefania Stella, Silvia Rita Vitale, Francesco Frasca
Publikováno v:
Anticancer Research. 38:6653-6662
Background Poorly differentiated (PDTC) and anaplastic thyroid (ATC) cancer cells are characterized by the acquisition of epigenetic abnormalities, leading to the silencing of both the sodium iodide co-transporter and the Coxsackie adenovirus recepto
Autor:
Andrew H. Sims, Ernestina Marianna De Francesco, Rosamaria Lappano, Antonino Belfiore, Veronica Vella, Francesca Cirillo, Maria Grazia Muoio, Marianna Talia, Marika Giuliano, Marcello Maggiolini, Livia Manzella
Publikováno v:
Cancers
Volume 13
Issue 4
Cancers, Vol 13, Iss 621, p 621 (2021)
Muoio, M G, Talia, M, Lappano, R, Sims, A H, Vella, V, Cirillo, F, Manzella, L, Giuliano, M, Maggiolini, M, Belfiore, A & De Francesco, E M 2021, ' Activation of the S100A7/RAGE Pathway by IGF-1 Contributes to Angiogenesis in Breast Cancer ', Cancers, vol. 13, no. 4, pp. 621 . https://doi.org/10.3390/cancers13040621
Volume 13
Issue 4
Cancers, Vol 13, Iss 621, p 621 (2021)
Muoio, M G, Talia, M, Lappano, R, Sims, A H, Vella, V, Cirillo, F, Manzella, L, Giuliano, M, Maggiolini, M, Belfiore, A & De Francesco, E M 2021, ' Activation of the S100A7/RAGE Pathway by IGF-1 Contributes to Angiogenesis in Breast Cancer ', Cancers, vol. 13, no. 4, pp. 621 . https://doi.org/10.3390/cancers13040621
Simple Summary Breast cancer mortality is increased in patients affected by metabolic disorders associated with dysregulation of the Insulin-like growth factor-1 (IGF-1) axis, like obesity and type-2 diabetes. Despite the oncogenic role of this compl
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Frontiers in Endocrinology
Frontiers in Endocrinology