Zobrazeno 21 - 30
of 102
pro vyhledávání: '"Vergnaud AC"'
Autor:
Claudia Agnoli, Eiliv Lund, Jytte Halkjær, Paolo Vineis, Nadia Slimani, Laudina Rodríguez, Ingegerd Johansson, Anne M. May, Pilar Amiano, Bas Bueno-de-Mesquita, José María Huerta, Dagrun Engeset, Anne Tjønneland, Françoise Clavel-Chapelon, Heiner Boeing, Marie-Christine Boutron-Ruault, Dora Romaguera, Rosario Tumino, Traci Mouw, Androniki Naska, Marianne Uhre Jakobsen, Nicholas J. Wareham, Elisabeth Couto, Anne-Claire Vergnaud, Frederike L. Büchner, Teresa Norat, Kim Overvad, Philippos Orfanos, Silke Hermann, Timothy J. Key, Vanessa Cottet, Elisabet Wirfält, Salvatore Panico, Jian'an Luan, Antonia Trichopoulou, Veronica Hellstrom, Aurelio Barricarte, Antonio Agudo, Sabina Rinaldi, Jonas Manjer, Noémie Travier, Andreani D. Odysseos, Domenico Palli, Brian Buijsse, María José Sánchez, Tonje Braaten, Sabine Rohrmann, Petra H.M. Peeters, Elio Riboli, E. A. Spencer
Publikováno v:
The American Journal of Clinical Nutrition, 92, 398-407
Vergnaud, A-C, Norat, T, Romaguera, D, Mouw, T, May, A M, Travier, N, Luan, J, Wareham, N, Slimani, N, Rinaldi, S, Couto, E, Clavel-Chapelon, F, Boutron-Ruault, M-C, Cottet, V, Palli, D, Agnoli, C, Panico, S, Tumino, R, Vineis, P, Agudo, A, Rodriguez, L, Sanchez, M J, Amiano, P, Barricarte, A, Huerta, J M, Key, T J, Spencer, E A, Bueno-de-Mesquita, B, Büchner, F L, Orfanos, P, Naska, A, Trichopoulou, A, Rohrmann, S, Hermann, S, Boeing, H, Buijsse, B, Johansson, I, Hellstrom, V, Manjer, J, Wirfält, E, Jakobsen, M U, Overvad, K, Tjonneland, A, Halkjær, J, Lund, E, Braaten, T, Engeset, D, Odysseos, A, Riboli, E & Peeters, P H 2010, ' Meat consumption and prospective weight change in participants of the EPIC-PANACEA study ', American Journal of Clinical Nutrition, vol. 92, no. 2, pp. 398-407 . https://doi.org/10.3945/ajcn.2009.28713
The American Journal of Clinical Nutrition, 92, 2, pp. 398-407
Vergnaud, A-C, Norat, T, Romaguera, D, Mouw, T, May, A M, Travier, N, Luan, J, Wareham, N, Slimani, N, Rinaldi, S, Couto, E, Clavel-Chapelon, F, Boutron-Ruault, M-C, Cottet, V, Palli, D, Agnoli, C, Panico, S, Tumino, R, Vineis, P, Agudo, A, Rodriguez, L, Sanchez, M J, Amiano, P, Barricarte, A, Huerta, J M, Key, T J, Spencer, E A, Bueno-de-Mesquita, B, Büchner, F L, Orfanos, P, Naska, A, Trichopoulou, A, Rohrmann, S, Hermann, S, Boeing, H, Buijsse, B, Johansson, I, Hellstrom, V, Manjer, J, Wirfält, E, Jakobsen, M U, Overvad, K, Tjonneland, A, Halkjær, J, Lund, E, Braaten, T, Engeset, D, Odysseos, A, Riboli, E & Peeters, P H 2010, ' Meat consumption and prospective weight change in participants of the EPIC-PANACEA study ', American Journal of Clinical Nutrition, vol. 92, no. 2, pp. 398-407 . https://doi.org/10.3945/ajcn.2009.28713
The American Journal of Clinical Nutrition, 92, 2, pp. 398-407
Contains fulltext : 87610.pdf (Publisher’s version ) (Closed access) BACKGROUND: Meat intake may be related to weight gain because of its high energy and fat content. Some observational studies have shown that meat consumption is positively associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe4144da116207f9567003095c7398d3
http://hdl.handle.net/11588/376975
http://hdl.handle.net/11588/376975
Autor:
Sabina Sieri, Antonio Agudo, Petra H.M. Peeters, Françoise Clavel-Chapelon, Kim Overvad, H. Bas Bueno-de-Mesquita, Timothy J. Key, Elio Riboli, Louise Hansen, Lambertus A. Kiemeney, María José Sánchez, Paolo Vineis, Ute Nöthlings, Nerea Larrañaga, Dimosthenis Zylis, Domenico Palli, Wei W. Xun, Rosario Tumino, Eva Ardanaz, Torgny Rasmuson, Carla H. van Gils, Kay-Tee Khaw, Martine M. Ros, Inger T. Gram, Sabine Rohrmann, Marcial Argüelles, Elisabet Wirfält, Salvatore Panico, Tonje Braaten, Carmen Navarro, Frederike L. Büchner, Marie-Christine Boutron-Ruault, Vardis Dilis, Anne-Claire Vergnaud, Eiliv Lund, Marina Touillaud, Rudolf Kaaks, Jonas Manjer, Göran Hallmans, Nicholas J. Wareham, Heiner Boeing, Nadia Slimani, Antonia Trichopoulou, Anne Tjønneland, Christina C. Dahm
Publikováno v:
Büchner, F L, Bueno-de-Mesquita, H B, Ros, M M, Overvad, K, Dahm, C C, Hansen, L, Tjønneland, A, Clavel-Chapelon, F, Boutron-Ruault, M-C, Touillaud, M, Kaaks, R, Rohrmann, S, Boeing, H, Nöthlings, U, Trichopoulou, A, Zylis, D, Dilis, V, Palli, D, Sieri, S, Vineis, P, Tumino, R, Panico, S, Peeters, P H M, van Gils, C H, Lund, E, Gram, I T, Braaten, T, Sánchez, M-J, Agudo, A, Larrañaga, N, Ardanaz, E, Navarro, C, Argüelles, M V, Manjer, J, Wirfält, E, Hallmans, G, Rasmuson, T, Key, T J, Khaw, K-T, Wareham, N, Slimani, N, Vergnaud, A-C, Xun, W W, Kiemeney, L A L M & Riboli, E 2010, ' Variety in Fruit and Vegetable Consumption and the Risk of Lung Cancer in the European Prospective Investigation into Cancer and Nutrition ', Cancer Epidemiology, Biomarkers & Prevention, vol. 19, no. 9, pp. 2278-86 . https://doi.org/10.1158/1055-9965.EPI-10-0489
Cancer Epidemiology, Biomarkers & Prevention, 19, 9, pp. 2278-86
Cancer Epidemiology, Biomarkers & Prevention, 19, 2278-86
Cancer Epidemiology, Biomarkers & Prevention, 19, 9, pp. 2278-86
Cancer Epidemiology, Biomarkers & Prevention, 19, 2278-86
Background: We investigated whether a varied consumption of vegetables and fruits is associated with lower lung cancer risk in the European Prospective Investigation into Cancer and Nutrition study. Methods: After a mean follow-up of 8.7 years, 1,613
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9de734847c7115b6eecad54fa56ef381
https://pure.au.dk/portal/da/publications/variety-in-fruit-and-vegetable-consumption-and-the-risk-of-lung-cancer-in-the-european-prospective-investigation-into-cancer-and-nutrition(d6531b60-b758-11df-b4b4-000ea68e967b).html
https://pure.au.dk/portal/da/publications/variety-in-fruit-and-vegetable-consumption-and-the-risk-of-lung-cancer-in-the-european-prospective-investigation-into-cancer-and-nutrition(d6531b60-b758-11df-b4b4-000ea68e967b).html
Autor:
Surendran P; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Rutherford Fund Fellow, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Feofanova EV; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Lahrouchi N; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Amsterdam UMC, University of Amsterdam, Heart Center, Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences Amsterdam, Amsterdam, the Netherlands., Ntalla I; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Karthikeyan S; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Cook J; Department of Biostatistics, University of Liverpool, Liverpool, UK., Chen L; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Mifsud B; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar., Yao C; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Kraja AT; Division of Statistical Genomics, Department of Genetics and Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA., Cartwright JH; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Hellwege JN; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Giri A; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA.; Division of Quantitative Sciences, Department of Obstetrics & Gynecology, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Tragante V; Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.; deCODE genetics/Amgen, Inc, Reykjavik, Iceland., Thorleifsson G; deCODE genetics/Amgen, Inc, Reykjavik, Iceland., Liu DJ; Institute of Personalized Medicine, Penn State College of Medicine, Hershey, PA, USA., Prins BP; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Stewart ID; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Cabrera CP; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK., Eales JM; Division of Cardiovascular Sciences, Faculty of Medicine, Biology and Health, University of Manchester, Manchester, UK., Akbarov A; Division of Cardiovascular Sciences, Faculty of Medicine, Biology and Health, University of Manchester, Manchester, UK., Auer PL; Joseph J Zilber School of Public Health, University of Wisconsin, Milwaukee, WI, USA., Bielak LF; Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Braithwaite VS; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.; MRC Nutrition and Bone Health Group, University of Cambridge, Cambridge, UK.; MRC Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, Gambia., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Daw EW; Division of Statistical Genomics, Department of Genetics and Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA., Warren HR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK., Drenos F; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, London, UK.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK., Nielsen SF; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Fauman EB; Internal Medicine Research Unit, Pfizer, Cambridge, MA, USA., Fava C; Department of Medicine, University of Verona, Verona, Italy.; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden., Ferreira T; The Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK., Foley CN; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; MRC Biostatistics Unit, University of Cambridge, Cambridge, UK., Franceschini N; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Gao H; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK., Giannakopoulou O; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Centre for Genomic Health, Queen Mary University of London, London, UK.; Division of Psychiatry, University College of London, London, UK., Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA., Gudbjartsson DF; deCODE genetics/Amgen, Inc, Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland., Guo X; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Harris SE; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK., Havulinna AS; Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK.; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Helgadottir A; deCODE genetics/Amgen, Inc, Reykjavik, Iceland., Huffman JE; MRC Human Genetics Unit, IGMM, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Hwang SJ; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.; Boston University and National Heart, Lung and Blood Institute Framingham Heart Study, Framingham, MA, USA., Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Centre for Genomic Health, Life Sciences, Queen Mary University of London, London, UK., Kontto J; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Larson MG; Boston University and National Heart, Lung and Blood Institute Framingham Heart Study, Framingham, MA, USA.; Biostatistics Department, Boston University School of Public Health, Boston, MA, USA., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Lindström J; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Lotta LA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Lu Y; The Charles Bronfman Institute for Personalized Medicine at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN, USA., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Mahajan A; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Malerba G; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy., Masca NGD; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research Leicester Biomedical Research Centre, Leicester, UK., Mei H; Department of Data Science, School of Population Health, University of Mississippi Medical Center, Jackson, MS, USA., Menni C; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands., Mosen-Ansorena D; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, Ludwig-Maximilians-University Munich, Munich, Germany.; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU, Munich, Germany., Paré G; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada., Paul DS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK., Perola M; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland.; Clinical and Molecular Metabolism Research Program (CAMM), Faculty of Medicine, University of Helsinki, Helsinki, Finland., Poveda A; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital Malmö, Malmö, Sweden., Rauramaa R; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Richard M; Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Richardson TG; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Sepúlveda N; Department of Infection Biology, Faculty of Tropical and Infectious Diseases, London School of Hygiene & Tropical Medicine, London, UK.; Centre of Statistics and Applications of University of Lisbon, Lisbon, Portugal., Sim X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Saw Swee Hock School of Public Health, National University of, Singapore, Singapore., Smith AV; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA., Smith JA; Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Staley JR; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Stanáková A; University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Sulem P; deCODE genetics/Amgen, Inc, Reykjavik, Iceland., Thériault S; Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.; Department of Molecular Biology, Medical Biochemistry and Pathology, Laval University, Quebec City, Quebec, Canada., Thorsteinsdottir U; deCODE genetics/Amgen, Inc, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Trompet S; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands.; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Varga TV; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital Malmö, Malmö, Sweden., Velez Edwards DR; Vanderbilt Genetics Institute, Vanderbilt Epidemiology Center, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Tennessee Valley Health Systems VA, Nashville, TN, USA., Veronesi G; Research Center in Epidemiology and Preventive Medicine, Department of Medicine and Surgery, University of Insubria, Varese, Italy., Weiss S; Interfaculty Institute for Genetics and Functional Genomics, University Medicine and University of Greifswald, Greifswald, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Willems SM; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Yao J; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Young R; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK., Yu B; Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA., Zhang W; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK., Zhao JH; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK., Zhao W; Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, USA., Zhao W; Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA., Evangelou E; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Aeschbacher S; Division of Cardiology, University Hospital, Basel, Switzerland., Asllanaj E; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; Department of Epidemiology, Erasmus MC, University Medical Centre, Rotterdam, the Netherlands., Blankenberg S; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Department of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany.; University Medical Center Hamburg Eppendorf, Hamburg, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Hamburg/Kiel/Lübeck, Hamburg, Germany., Bonnycastle LL; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD, USA., Bork-Jensen J; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Brandslund I; Department of Clinical Biochemistry, Lillebaelt Hospital, Vejle, Denmark.; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Braund PS; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research Leicester Biomedical Research Centre, Leicester, UK., Burgess S; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; MRC Biostatistics Unit, University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK., Cho K; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA.; Division of Aging, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Christensen C; Medical Department, Lillebaelt Hospital, Vejle, Denmark., Connell J; University of Dundee, Ninewells Hospital & Medical School, Dundee, UK., Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Dominiczak AF; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland, UK., Dörr M; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany., Eiriksdottir G; Icelandic Heart Association, Kopavogur, Iceland., Farmaki AE; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.; Department of Population Science and Experimental Medicine, Institute of Cardiovascular Science, University College London, London, UK., Gaziano JM; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA.; Division of Aging, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Grove ML; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Hallmans G; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Have CT; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Heiss G; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Jørgensen ME; Steno Diabetes Center, Copenhagen, Gentofte, Denmark., Jousilahti P; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Kajantie E; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland.; PEDEGO Research Unit, MRC Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.; Hospital for Children and Adolescents, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland., Kamat M; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK., Käräjämäki A; Department of Primary Health Care, Vaasa Central Hospital, Vaasa, Finland.; Diabetes Center, Vaasa Health Care Center, Vaasa, Finland., Karpe F; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Koistinen HA; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland.; Department of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Kovesdy CP; Nephrology Section, Memphis VA Medical Center, Memphis, TN, USA., Kuulasmaa K; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Laatikainen T; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland.; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Lannfelt L; Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden., Lee IT; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan.; School of Medicine, , Chung Shan Medical University, Taichung, Taiwan.; College of Science, Tunghai University, Taichung, Taiwan., Lee WJ; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.; Department of Social Work, Tunghai University, Taichung, Taiwan., Linneberg A; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Martin LW; George Washington University School of Medicine and Health Sciences, Washington DC, USA., Moitry M; Department of Public health, Strasbourg University Hospital, University of Strasbourg, Strasbourg, France., Nadkarni G; The Charles Bronfman Institute for Personalized Medicine at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Neville MJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Palmer CNA; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland, UK., Papanicolaou GJ; Epidemiology Branch, NHLBI, Bethesda, MD, USA., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Peters J; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Department of Immunology and Inflammation, Imperial College London, London, UK., Poulter N; International Centre for Circulatory Health, Imperial College London, London, UK., Rasheed A; Centre for Non-Communicable Diseases, Karachi, Pakistan., Rasmussen KL; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Rayner NW; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Mägi R; Institute of Genomics, University of Tartu, Tartu, Estonia., Renström F; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital Malmö, Malmö, Sweden.; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Rettig R; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Institute of Physiology, University Medicine Greifswald, Karlsburg, Germany., Rossouw J; Division of Cardiovascular Sciences, NHLBI, Bethesda, MD, USA., Schreiner PJ; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA., Sever PS; National Heart and Lung Institute, Imperial College London, London, UK., Sigurdsson EL; Department of Family Medicine, University of Iceland, Reykjavik, Iceland.; Development Centre for Primary Health Care in Iceland, Reykjavik, Iceland., Skaaby T; Center for Clinical Research and Disease Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark., Sun YV; Department of Epidemiology, Emory University Rollins School of Public Health, Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, USA., Sundstrom J; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Thorgeirsson G; deCODE genetics/Amgen, Inc, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Department of Internal Medicine, Division of Cardiology, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland., Esko T; Institute of Genomics, University of Tartu, Tartu, Estonia.; Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Trabetti E; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy., Tsao PS; VA Palo Alto Health Care System, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA., Tuomi T; Folkhälsan Research Centre, Helsinki, Finland.; Department of Endocrinology, Helsinki University Central Hospital, Helsinki, Finland.; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden Institute for Molecular Medicine Helsinki (FIMM), Helsinki University, Helsinki, Finland., Turner ST; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA., Tzoulaki I; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Vaartjes I; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, University of Utrecht, University of Utrecht, Utrecht, the Netherlands.; Center for Circulatory Health, University Medical Center Utrecht, University of Utrecht, Utrecht, the Netherlands., Vergnaud AC; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Willer CJ; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Wilson PWF; Atlanta VAMC and Emory Clinical Cardiovascular Research Institute, Atlanta, GA, USA., Witte DR; Department of Public Health, Aarhus University, Aarhus, Denmark.; Danish Diabetes Academy, Odense, Denmark.; Steno Diabetes Center Aarhus, Aarhus, Denmark., Yonova-Doing E; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Zhang H; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA., Aliya N; International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh., Almgren P; Department of Medicine, Lund University, Malmö, Sweden., Amouyel P; Univ Lille, U1167 - RID-AGE - Facteurs de Risque et Déterminants Moléculaires des Maladies Liées au Vieillissement, Lille, France.; INSERM, U1167, Lille, France.; CHU Lille, U1167, Lille, France.; Institut Pasteur de Lille, U1167, Lille, France., Asselbergs FW; Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK.; Health Data Research UK, Institute of Health Informatics, University College London, London, UK., Barnes MR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK., Blakemore AI; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, London, UK.; Section of Investigative Medicine, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, UK., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Bots ML; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, University of Utrecht, University of Utrecht, Utrecht, the Netherlands.; Center for Circulatory Health, University Medical Center Utrecht, University of Utrecht, Utrecht, the Netherlands., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Buring JE; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Chambers JC; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Imperial College Healthcare NHS Trust, London, UK., Chen YI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Chowdhury R; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Non-communicable Disease Research (CNCR), Dhaka, Bangladesh., Conen D; Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.; Cardiovascular Research Institute Basel, Basel, Switzerland., Correa A; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Davey Smith G; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Boer RA; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, the Netherlands., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Dedoussis G; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK.; Centre for Genomic Health, Life Sciences, Queen Mary University of London, London, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., Di Angelantonio E; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK.; National Institute for Health Research (NIHR) Blood and Transplant Research Unit (BTRU) in Donor Health and Genomics at the University of Cambridge, Cambridge, UK., Elliott P; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK.; Health Data Research UK-London at Imperial College London, London, UK.; UKDRI, Dementia Research Institute at Imperial College London, London, UK.; British Heart Foundation (BHF) Centre of Research Excellence, Imperial College London, London, UK., Felix SB; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany., Ferrières J; Department of Cardiology and Department of Epidemiology, INSERM UMR 1027, Toulouse University Hospital, Toulouse, France., Ford I; Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK., Fornage M; Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA., Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital Malmö, Malmö, Sweden.; Department of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA.; Department of Public Health & Clinical Medicine, Umeå University, Umeå, Sweden.; Oxford Center for Diabetes, Endocrinology & Metabolism, Radcliff Department of Medicine, University of Oxford, Oxford, UK., Franks S; Institute of Reproductive & Developmental Biology, Imperial College London, London, UK., Frossard P; Centre for Non-Communicable Diseases, Karachi, Pakistan., Gambaro G; Division of Nephrology, Department of Medicine, University of Verona, Verona, Italy., Gaunt TR; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Groop L; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden.; Institute for Molecular Medicine Helsinki (FIMM), Helsinki University, Helsinki, Finland., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute of Aging, Bethesda, MD, USA., Hayward C; MRC Human Genetics Unit, IGMM, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Hennig BJ; MRC Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, Gambia.; Wellcome Trust, London, UK., Herzig KH; Institute of Biomedicine, Medical Research Center (MRC), University of Oulu, and University Hospital Oulu, Oulu, Finland.; Department of Gastroenterology and Metabolism, Poznan University of Medical Sciences, Poznan, Poland., Ingelsson E; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA.; Stanford Diabetes Research Center, Stanford University, Stanford, CA, USA., Tuomilehto J; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Saudi Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia.; National Institute of Public Health, Madrid, Spain., Järvelin MR; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, London, UK.; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK.; Unit of Primary Care, Oulu University Hospital, Kajaanintie, Oulu, Finland.; Center for Life-Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Netherlands Heart Institute, Utrecht, the Netherlands., Kardia SLR; Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA., Kee F; Centre for Public Health, Queens University Belfast, Belfast, UK., Kooner JS; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK.; National Heart and Lung Institute, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, London, UK., Kooperberg C; Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seattle, WA, USA., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute of Aging, Bethesda, MD, USA., Lind L; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Loos RJF; The Charles Bronfman Institute for Personalized Medicine at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Majumder AAS; National Institute of Cardiovascular Diseases, Sher-e-Bangla Nagar, Dhaka, Bangladesh., Laakso M; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., McCarthy MI; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK.; Genentech, South San Francisco, San Francisco, CA, USA., Melander O; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Murray AD; The Institute of Medical Sciences, Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, UK., Nordestgaard BG; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Orho-Melander M; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden., Packard CJ; University of Glasgow, Glasgow, UK., Padmanabhan S; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK., Palmas W; Department of Medicine, Columbia University Medical Center, New York, NY, USA., Polasek O; Department of Public Health, University of Split School of Medicine, Split, Croatia., Porteous DJ; Centre for Genomic and Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh, UK., Prentice AM; MRC Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, Gambia.; MRC International Nutrition Group at London School of Hygiene and Tropical Medicine, Keppel St, London, UK., Province MA; Division of Statistical Genomics, Department of Genetics and Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA., Relton CL; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Rice K; Department of Biostatistics, University of Washington, Seattle, WA, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Rolandsson O; Department of Public Health & Clinical Medicine, Umeå University, Umeå, Sweden., Rosendaal FR; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Rotter JI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Scotland, UK., Salomaa V; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research Leicester Biomedical Research Centre, Leicester, UK., Sattar N; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland, UK., Sheu WH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan.; School of Medicine, National Defense Medical Center, Taipei, Taiwan.; Institute of Medical Technology, National Chung-Hsing University, Taichung, Taiwan., Smith BH; Division of Population Health and Genomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Soranzo N; National Institute for Health Research (NIHR) Blood and Transplant Research Unit (BTRU) in Donor Health and Genomics at the University of Cambridge, Cambridge, UK.; Department of Human Genetics, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Research Centre, University of Edinburgh, Edinburgh, UK., Sebert S; Center for Life-Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland., Taylor KD; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Lakka TA; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.; Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio, Finland., Timpson NJ; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Tobin MD; National Institute for Health Research Leicester Biomedical Research Centre, Leicester, UK.; Department of Health Sciences, University of Leicester, Leicester, UK., van der Harst P; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, the Netherlands.; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, the Netherlands., van der Meer P; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, the Netherlands., Ramachandran VS; Boston University and National Heart, Lung and Blood Institute Framingham Heart Study, Framingham, MA, USA.; Boston University Schools of Medicine and Public Health, Boston, MA, USA., Verweij N; University Medical Center Groningen, Groningen, the Netherlands., Virtamo J; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Völker U; Interfaculty Institute for Genetics and Functional Genomics, University Medicine and University of Greifswald, Greifswald, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Weir DR; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Zeggini E; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.; Institute of Translational Genomics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; TUM School of Medicine, Technical University of Munich and Klinikum Rechts der Isar, Munich, Germany., Charchar FJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; Health Innovation and Transformation Center, Federation University Australia, Ballarat, Victoria, Australia.; Department of Physiology, University of Melbourne, Melbourne, Victoria, Australia., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Tomaszewski M; Division of Cardiovascular Sciences, Faculty of Medicine, Biology and Health, University of Manchester, Manchester, UK.; Division of Medicine, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Butterworth AS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK.; National Institute for Health Research (NIHR) Blood and Transplant Research Unit (BTRU) in Donor Health and Genomics at the University of Cambridge, Cambridge, UK., Caulfield MJ; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK., Danesh J; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK.; National Institute for Health Research (NIHR) Blood and Transplant Research Unit (BTRU) in Donor Health and Genomics at the University of Cambridge, Cambridge, UK.; Department of Human Genetics, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Edwards TL; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Holm H; deCODE genetics/Amgen, Inc, Reykjavik, Iceland., Hung AM; VA Tennessee Valley Healthcare System, Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt Center for Kidney Disease, Vanderbilt University Medical Center, Nashville, TN, USA., Lindgren CM; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; The Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Liu C; Boston University School of Public Health, Boston, MA, USA., Manning AK; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Clinical and Translational Epidemiology Unit, Mongan Institute, Massachusetts General Hospital, Boston, MA, USA., Morris AP; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, University of Manchester, Manchester, UK., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., O'Donnell CJ; VA Boston Healthcare, Section of Cardiology and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA., Saleheen D; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Center for Non-Communicable Diseases, Karachi, Pakistan., Stefansson K; deCODE genetics/Amgen, Inc, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Levy D; Boston University and National Heart, Lung and Blood Institute Framingham Heart Study, Framingham, MA, USA.; Population Sciences, Branch, National Heart, Lung, and Blood Institute, National Institute of Health, Bethesda, MD, USA., Newton-Cheh C; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Munroe PB; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. p.b.munroe@qmul.ac.uk.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK. p.b.munroe@qmul.ac.uk., Howson JMM; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. JMMHowson@gmail.com.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK. JMMHowson@gmail.com.; Department of Genetics, Novo Nordisk Research Centre Oxford, Oxford, UK. JMMHowson@gmail.com.; Novo Nordisk Research Centre Oxford, Novo Nordisk Ltd, Oxford, UK. JMMHowson@gmail.com.
Publikováno v:
Nature genetics [Nat Genet] 2021 May; Vol. 53 (5), pp. 762.
Autor:
Surendran P; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Rutherford Fund Fellow, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Feofanova EV; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Lahrouchi N; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Amsterdam UMC, University of Amsterdam, Heart Center, Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences Amsterdam, Amsterdam, the Netherlands., Ntalla I; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Karthikeyan S; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Cook J; Department of Biostatistics, University of Liverpool, Liverpool, UK., Chen L; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Mifsud B; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar., Yao C; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Kraja AT; Division of Statistical Genomics, Department of Genetics and Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA., Cartwright JH; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Hellwege JN; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Giri A; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA.; Division of Quantitative Sciences, Department of Obstetrics & Gynecology, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Tragante V; Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.; deCODE genetics/Amgen, Inc, Reykjavik, Iceland., Thorleifsson G; deCODE genetics/Amgen, Inc, Reykjavik, Iceland., Liu DJ; Institute of Personalized Medicine, Penn State College of Medicine, Hershey, PA, USA., Prins BP; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Stewart ID; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Cabrera CP; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK., Eales JM; Division of Cardiovascular Sciences, Faculty of Medicine, Biology and Health, University of Manchester, Manchester, UK., Akbarov A; Division of Cardiovascular Sciences, Faculty of Medicine, Biology and Health, University of Manchester, Manchester, UK., Auer PL; Joseph J Zilber School of Public Health, University of Wisconsin, Milwaukee, WI, USA., Bielak LF; Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Braithwaite VS; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.; MRC Nutrition and Bone Health Group, University of Cambridge, Cambridge, UK.; MRC Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, Gambia., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Daw EW; Division of Statistical Genomics, Department of Genetics and Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA., Warren HR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK., Drenos F; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, London, UK.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK., Nielsen SF; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Fauman EB; Internal Medicine Research Unit, Pfizer, Cambridge, MA, USA., Fava C; Department of Medicine, University of Verona, Verona, Italy.; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden., Ferreira T; The Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK., Foley CN; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; MRC Biostatistics Unit, University of Cambridge, Cambridge, UK., Franceschini N; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Gao H; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK., Giannakopoulou O; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Centre for Genomic Health, Queen Mary University of London, London, UK.; Division of Psychiatry, University College of London, London, UK., Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA., Gudbjartsson DF; deCODE genetics/Amgen, Inc, Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland., Guo X; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Harris SE; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK., Havulinna AS; Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK.; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Helgadottir A; deCODE genetics/Amgen, Inc, Reykjavik, Iceland., Huffman JE; MRC Human Genetics Unit, IGMM, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Hwang SJ; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.; Boston University and National Heart, Lung and Blood Institute Framingham Heart Study, Framingham, MA, USA., Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Centre for Genomic Health, Life Sciences, Queen Mary University of London, London, UK., Kontto J; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Larson MG; Boston University and National Heart, Lung and Blood Institute Framingham Heart Study, Framingham, MA, USA.; Biostatistics Department, Boston University School of Public Health, Boston, MA, USA., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Lindström J; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Lotta LA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Lu Y; The Charles Bronfman Institute for Personalized Medicine at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN, USA., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Mahajan A; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Malerba G; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy., Masca NGD; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research Leicester Biomedical Research Centre, Leicester, UK., Mei H; Department of Data Science, School of Population Health, University of Mississippi Medical Center, Jackson, MS, USA., Menni C; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands., Mosen-Ansorena D; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, Ludwig-Maximilians-University Munich, Munich, Germany.; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU, Munich, Germany., Paré G; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada., Paul DS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK., Perola M; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland.; Clinical and Molecular Metabolism Research Program (CAMM), Faculty of Medicine, University of Helsinki, Helsinki, Finland., Poveda A; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital Malmö, Malmö, Sweden., Rauramaa R; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Richard M; Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Richardson TG; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Sepúlveda N; Department of Infection Biology, Faculty of Tropical and Infectious Diseases, London School of Hygiene & Tropical Medicine, London, UK.; Centre of Statistics and Applications of University of Lisbon, Lisbon, Portugal., Sim X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Saw Swee Hock School of Public Health, National University of, Singapore, Singapore., Smith AV; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA., Smith JA; Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Staley JR; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Stanáková A; University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Sulem P; deCODE genetics/Amgen, Inc, Reykjavik, Iceland., Thériault S; Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.; Department of Molecular Biology, Medical Biochemistry and Pathology, Laval University, Quebec City, Quebec, Canada., Thorsteinsdottir U; deCODE genetics/Amgen, Inc, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Trompet S; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands.; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Varga TV; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital Malmö, Malmö, Sweden., Velez Edwards DR; Vanderbilt Genetics Institute, Vanderbilt Epidemiology Center, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Tennessee Valley Health Systems VA, Nashville, TN, USA., Veronesi G; Research Center in Epidemiology and Preventive Medicine, Department of Medicine and Surgery, University of Insubria, Varese, Italy., Weiss S; Interfaculty Institute for Genetics and Functional Genomics, University Medicine and University of Greifswald, Greifswald, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Willems SM; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Yao J; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Young R; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK., Yu B; Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA., Zhang W; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK., Zhao JH; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK., Zhao W; Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, USA., Zhao W; Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA., Evangelou E; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Aeschbacher S; Division of Cardiology, University Hospital, Basel, Switzerland., Asllanaj E; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; Department of Epidemiology, Erasmus MC, University Medical Centre, Rotterdam, the Netherlands., Blankenberg S; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Department of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany.; University Medical Center Hamburg Eppendorf, Hamburg, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Hamburg/Kiel/Lübeck, Hamburg, Germany., Bonnycastle LL; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD, USA., Bork-Jensen J; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Brandslund I; Department of Clinical Biochemistry, Lillebaelt Hospital, Vejle, Denmark.; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Braund PS; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research Leicester Biomedical Research Centre, Leicester, UK., Burgess S; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; MRC Biostatistics Unit, University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK., Cho K; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA.; Division of Aging, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Christensen C; Medical Department, Lillebaelt Hospital, Vejle, Denmark., Connell J; University of Dundee, Ninewells Hospital & Medical School, Dundee, UK., Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Dominiczak AF; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland, UK., Dörr M; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany., Eiriksdottir G; Icelandic Heart Association, Kopavogur, Iceland., Farmaki AE; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.; Department of Population Science and Experimental Medicine, Institute of Cardiovascular Science, University College London, London, UK., Gaziano JM; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA.; Division of Aging, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Grove ML; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Hallmans G; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Have CT; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Heiss G; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Jørgensen ME; Steno Diabetes Center, Copenhagen, Gentofte, Denmark., Jousilahti P; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Kajantie E; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland.; PEDEGO Research Unit, MRC Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.; Hospital for Children and Adolescents, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland., Kamat M; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK., Käräjämäki A; Department of Primary Health Care, Vaasa Central Hospital, Vaasa, Finland.; Diabetes Center, Vaasa Health Care Center, Vaasa, Finland., Karpe F; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Koistinen HA; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland.; Department of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Kovesdy CP; Nephrology Section, Memphis VA Medical Center, Memphis, TN, USA., Kuulasmaa K; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Laatikainen T; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland.; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Lannfelt L; Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden., Lee IT; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan.; School of Medicine, , Chung Shan Medical University, Taichung, Taiwan.; College of Science, Tunghai University, Taichung, Taiwan., Lee WJ; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.; Department of Social Work, Tunghai University, Taichung, Taiwan., Linneberg A; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Martin LW; George Washington University School of Medicine and Health Sciences, Washington DC, USA., Moitry M; Department of Public health, Strasbourg University Hospital, University of Strasbourg, Strasbourg, France., Nadkarni G; The Charles Bronfman Institute for Personalized Medicine at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Neville MJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Palmer CNA; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland, UK., Papanicolaou GJ; Epidemiology Branch, NHLBI, Bethesda, MD, USA., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Peters J; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Department of Immunology and Inflammation, Imperial College London, London, UK., Poulter N; International Centre for Circulatory Health, Imperial College London, London, UK., Rasheed A; Centre for Non-Communicable Diseases, Karachi, Pakistan., Rasmussen KL; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Rayner NW; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Mägi R; Institute of Genomics, University of Tartu, Tartu, Estonia., Renström F; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital Malmö, Malmö, Sweden.; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Rettig R; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Institute of Physiology, University Medicine Greifswald, Karlsburg, Germany., Rossouw J; Division of Cardiovascular Sciences, NHLBI, Bethesda, MD, USA., Schreiner PJ; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA., Sever PS; National Heart and Lung Institute, Imperial College London, London, UK., Sigurdsson EL; Department of Family Medicine, University of Iceland, Reykjavik, Iceland.; Development Centre for Primary Health Care in Iceland, Reykjavik, Iceland., Skaaby T; Center for Clinical Research and Disease Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark., Sun YV; Department of Epidemiology, Emory University Rollins School of Public Health, Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, USA., Sundstrom J; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Thorgeirsson G; deCODE genetics/Amgen, Inc, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Department of Internal Medicine, Division of Cardiology, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland., Esko T; Institute of Genomics, University of Tartu, Tartu, Estonia.; Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Trabetti E; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy., Tsao PS; VA Palo Alto Health Care System, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA., Tuomi T; Folkhälsan Research Centre, Helsinki, Finland.; Department of Endocrinology, Helsinki University Central Hospital, Helsinki, Finland.; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden Institute for Molecular Medicine Helsinki (FIMM), Helsinki University, Helsinki, Finland., Turner ST; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA., Tzoulaki I; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Vaartjes I; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, University of Utrecht, University of Utrecht, Utrecht, the Netherlands.; Center for Circulatory Health, University Medical Center Utrecht, University of Utrecht, Utrecht, the Netherlands., Vergnaud AC; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Willer CJ; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Wilson PWF; Atlanta VAMC and Emory Clinical Cardiovascular Research Institute, Atlanta, GA, USA., Witte DR; Department of Public Health, Aarhus University, Aarhus, Denmark.; Danish Diabetes Academy, Odense, Denmark.; Steno Diabetes Center Aarhus, Aarhus, Denmark., Yonova-Doing E; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Zhang H; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA., Aliya N; International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh., Almgren P; Department of Medicine, Lund University, Malmö, Sweden., Amouyel P; Univ Lille, U1167 - RID-AGE - Facteurs de Risque et Déterminants Moléculaires des Maladies Liées au Vieillissement, Lille, France.; INSERM, U1167, Lille, France.; CHU Lille, U1167, Lille, France.; Institut Pasteur de Lille, U1167, Lille, France., Asselbergs FW; Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK.; Health Data Research UK, Institute of Health Informatics, University College London, London, UK., Barnes MR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK., Blakemore AI; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, London, UK.; Section of Investigative Medicine, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, UK., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Bots ML; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, University of Utrecht, University of Utrecht, Utrecht, the Netherlands.; Center for Circulatory Health, University Medical Center Utrecht, University of Utrecht, Utrecht, the Netherlands., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Buring JE; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Chambers JC; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Imperial College Healthcare NHS Trust, London, UK., Chen YI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Chowdhury R; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Non-communicable Disease Research (CNCR), Dhaka, Bangladesh., Conen D; Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.; Cardiovascular Research Institute Basel, Basel, Switzerland., Correa A; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Davey Smith G; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Boer RA; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, the Netherlands., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Dedoussis G; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK.; Centre for Genomic Health, Life Sciences, Queen Mary University of London, London, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., Di Angelantonio E; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK.; National Institute for Health Research (NIHR) Blood and Transplant Research Unit (BTRU) in Donor Health and Genomics at the University of Cambridge, Cambridge, UK., Elliott P; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK.; Health Data Research UK-London at Imperial College London, London, UK.; UKDRI, Dementia Research Institute at Imperial College London, London, UK.; British Heart Foundation (BHF) Centre of Research Excellence, Imperial College London, London, UK., Felix SB; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany., Ferrières J; Department of Cardiology and Department of Epidemiology, INSERM UMR 1027, Toulouse University Hospital, Toulouse, France., Ford I; Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK., Fornage M; Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA., Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital Malmö, Malmö, Sweden.; Department of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA.; Department of Public Health & Clinical Medicine, Umeå University, Umeå, Sweden.; Oxford Center for Diabetes, Endocrinology & Metabolism, Radcliff Department of Medicine, University of Oxford, Oxford, UK., Franks S; Institute of Reproductive & Developmental Biology, Imperial College London, London, UK., Frossard P; Centre for Non-Communicable Diseases, Karachi, Pakistan., Gambaro G; Division of Nephrology, Department of Medicine, University of Verona, Verona, Italy., Gaunt TR; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Groop L; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden.; Institute for Molecular Medicine Helsinki (FIMM), Helsinki University, Helsinki, Finland., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute of Aging, Bethesda, MD, USA., Hayward C; MRC Human Genetics Unit, IGMM, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Hennig BJ; MRC Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, Gambia.; Wellcome Trust, London, UK., Herzig KH; Institute of Biomedicine, Medical Research Center (MRC), University of Oulu, and University Hospital Oulu, Oulu, Finland.; Department of Gastroenterology and Metabolism, Poznan University of Medical Sciences, Poznan, Poland., Ingelsson E; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA.; Stanford Diabetes Research Center, Stanford University, Stanford, CA, USA., Tuomilehto J; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Saudi Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia.; National Institute of Public Health, Madrid, Spain., Järvelin MR; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, London, UK.; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK.; Unit of Primary Care, Oulu University Hospital, Kajaanintie, Oulu, Finland.; Center for Life-Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Netherlands Heart Institute, Utrecht, the Netherlands., Kardia SLR; Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA., Kee F; Centre for Public Health, Queens University Belfast, Belfast, UK., Kooner JS; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK.; National Heart and Lung Institute, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, London, UK., Kooperberg C; Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seattle, WA, USA., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute of Aging, Bethesda, MD, USA., Lind L; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Loos RJF; The Charles Bronfman Institute for Personalized Medicine at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Majumder AAS; National Institute of Cardiovascular Diseases, Sher-e-Bangla Nagar, Dhaka, Bangladesh., Laakso M; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., McCarthy MI; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK.; Genentech, South San Francisco, San Francisco, CA, USA., Melander O; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Murray AD; The Institute of Medical Sciences, Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, UK., Nordestgaard BG; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Orho-Melander M; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden., Packard CJ; University of Glasgow, Glasgow, UK., Padmanabhan S; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK., Palmas W; Department of Medicine, Columbia University Medical Center, New York, NY, USA., Polasek O; Department of Public Health, University of Split School of Medicine, Split, Croatia., Porteous DJ; Centre for Genomic and Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh, UK., Prentice AM; MRC Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, Gambia.; MRC International Nutrition Group at London School of Hygiene and Tropical Medicine, Keppel St, London, UK., Province MA; Division of Statistical Genomics, Department of Genetics and Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA., Relton CL; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Rice K; Department of Biostatistics, University of Washington, Seattle, WA, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Rolandsson O; Department of Public Health & Clinical Medicine, Umeå University, Umeå, Sweden., Rosendaal FR; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Rotter JI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Scotland, UK., Salomaa V; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research Leicester Biomedical Research Centre, Leicester, UK., Sattar N; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland, UK., Sheu WH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan.; School of Medicine, National Defense Medical Center, Taipei, Taiwan.; Institute of Medical Technology, National Chung-Hsing University, Taichung, Taiwan., Smith BH; Division of Population Health and Genomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Soranzo N; National Institute for Health Research (NIHR) Blood and Transplant Research Unit (BTRU) in Donor Health and Genomics at the University of Cambridge, Cambridge, UK.; Department of Human Genetics, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Research Centre, University of Edinburgh, Edinburgh, UK., Sebert S; Center for Life-Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland., Taylor KD; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Lakka TA; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.; Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio, Finland., Timpson NJ; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Tobin MD; National Institute for Health Research Leicester Biomedical Research Centre, Leicester, UK.; Department of Health Sciences, University of Leicester, Leicester, UK., van der Harst P; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, the Netherlands.; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, the Netherlands., van der Meer P; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, the Netherlands., Ramachandran VS; Boston University and National Heart, Lung and Blood Institute Framingham Heart Study, Framingham, MA, USA.; Boston University Schools of Medicine and Public Health, Boston, MA, USA., Verweij N; University Medical Center Groningen, Groningen, the Netherlands., Virtamo J; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Völker U; Interfaculty Institute for Genetics and Functional Genomics, University Medicine and University of Greifswald, Greifswald, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Weir DR; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Zeggini E; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.; Institute of Translational Genomics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; TUM School of Medicine, Technical University of Munich and Klinikum Rechts der Isar, Munich, Germany., Charchar FJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; Health Innovation and Transformation Center, Federation University Australia, Ballarat, Victoria, Australia.; Department of Physiology, University of Melbourne, Melbourne, Victoria, Australia., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Tomaszewski M; Division of Cardiovascular Sciences, Faculty of Medicine, Biology and Health, University of Manchester, Manchester, UK.; Division of Medicine, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Butterworth AS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK.; National Institute for Health Research (NIHR) Blood and Transplant Research Unit (BTRU) in Donor Health and Genomics at the University of Cambridge, Cambridge, UK., Caulfield MJ; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK., Danesh J; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK.; National Institute for Health Research (NIHR) Blood and Transplant Research Unit (BTRU) in Donor Health and Genomics at the University of Cambridge, Cambridge, UK.; Department of Human Genetics, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Edwards TL; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Holm H; deCODE genetics/Amgen, Inc, Reykjavik, Iceland., Hung AM; VA Tennessee Valley Healthcare System, Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt Center for Kidney Disease, Vanderbilt University Medical Center, Nashville, TN, USA., Lindgren CM; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; The Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Liu C; Boston University School of Public Health, Boston, MA, USA., Manning AK; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Clinical and Translational Epidemiology Unit, Mongan Institute, Massachusetts General Hospital, Boston, MA, USA., Morris AP; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, University of Manchester, Manchester, UK., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., O'Donnell CJ; VA Boston Healthcare, Section of Cardiology and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA., Saleheen D; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Center for Non-Communicable Diseases, Karachi, Pakistan., Stefansson K; deCODE genetics/Amgen, Inc, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Levy D; Boston University and National Heart, Lung and Blood Institute Framingham Heart Study, Framingham, MA, USA.; Population Sciences, Branch, National Heart, Lung, and Blood Institute, National Institute of Health, Bethesda, MD, USA., Newton-Cheh C; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Munroe PB; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. p.b.munroe@qmul.ac.uk.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK. p.b.munroe@qmul.ac.uk., Howson JMM; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. JMMHowson@gmail.com.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK. JMMHowson@gmail.com.; Department of Genetics, Novo Nordisk Research Centre Oxford, Oxford, UK. JMMHowson@gmail.com.; Novo Nordisk Research Centre Oxford, Novo Nordisk Ltd, Oxford, UK. JMMHowson@gmail.com.
Publikováno v:
Nature genetics [Nat Genet] 2020 Dec; Vol. 52 (12), pp. 1314-1332. Date of Electronic Publication: 2020 Nov 23.
Autor:
Elliott P; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK; MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK; NIHR Health Protection Research Unit on Health Effects of Environmental Hazards, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK; UK Dementia Research Institute (UK DRI) at Imperial College, Imperial College London, London, UK. Electronic address: p.elliott@imperial.ac.uk., Aresu M; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Gao H; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Vergnaud AC; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Heard A; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., McRobie D; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Spear J; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Singh D; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Kongsgård HW; Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Norway., Mbema C; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK; Consultant in Public Health, Lewisham Council, London, UK., Muller DC; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Publikováno v:
Environmental research [Environ Res] 2019 Aug; Vol. 175, pp. 148-155. Date of Electronic Publication: 2019 May 14.
Autor:
Gao H; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Aresu M; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Vergnaud AC; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., McRobie D; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Spear J; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Heard A; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Kongsgård HW; Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway., Singh D; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Muller DC; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Elliott P; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK. p.elliott@imperial.ac.uk.; MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK. p.elliott@imperial.ac.uk.; NIHR Health Protection Research Unit in Health Effects of Environmental Hazards, Imperial College London, London, UK. p.elliott@imperial.ac.uk.; UK Dementia Research Institute (DRI) at Imperial College, Imperial College London, London, UK. p.elliott@imperial.ac.uk.; Health Data Research-UK (HDR) London Centre at Imperial College, Imperial College London, London, UK. p.elliott@imperial.ac.uk.
Publikováno v:
British journal of cancer [Br J Cancer] 2019 Feb; Vol. 120 (3), pp. 375-378. Date of Electronic Publication: 2018 Dec 26.
Autor:
Evangelou E; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Warren HR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK., Mosen-Ansorena D; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Mifsud B; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Pazoki R; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Gao H; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK., Ntritsos G; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Dimou N; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Cabrera CP; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK., Karaman I; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Ng FL; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Evangelou M; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Mathematics, Imperial College London, London, UK., Witkowska K; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Tzanis E; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Hellwege JN; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Giri A; Vanderbilt Genetics Institute, Vanderbilt Epidemiology Center, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center; Tennessee Valley Health Systems VA, Nashville, TN, USA., Velez Edwards DR; Vanderbilt Genetics Institute, Vanderbilt Epidemiology Center, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center; Tennessee Valley Health Systems VA, Nashville, TN, USA., Sun YV; Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA, USA.; Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, USA., Cho K; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA.; Division of Aging, Department of Medicine, Brigham and Women's Hospital; Department of Medicine, Harvard Medical School, Boston, MA, USA., Gaziano JM; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA.; Division of Aging, Department of Medicine, Brigham and Women's Hospital; Department of Medicine, Harvard Medical School, Boston, MA, USA., Wilson PWF; Atlanta VAMC and Emory Clinical Cardiovascular Research Institute, Atlanta, GA, USA., Tsao PS; VA Palo Alto Health Care System, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA., Kovesdy CP; Nephrology Section, Memphis VA Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA., Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Mägi R; Estonian Genome Center, University of Tartu, Tartu, Estonia., Milani L; Estonian Genome Center, University of Tartu, Tartu, Estonia., Almgren P; Department Clinical Sciences, Malmö, Lund University, Malmö, Sweden., Boutin T; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Debette S; Department of Neurology, Bordeaux University Hospital, Bordeaux, France.; Univ. Bordeaux, Inserm, Bordeaux Population Health Research Center, CHU Bordeaux, Bordeaux, France., Ding J; Laboratory of Genetics and Genomics, NIA/NIH, Baltimore, MD, USA., Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA., Holliday EG; Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New Lambton Heights, New South Wales, Australia., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Lin WY; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Mangino M; Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK.; NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust, London, UK., Oldmeadow C; Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New Lambton Heights, New South Wales, Australia., Prins BP; Wellcome Trust Sanger Institute, Hinxton, UK., Qian Y; Laboratory of Genetics and Genomics, NIA/NIH, Baltimore, MD, USA., Sargurupremraj M; Univ. Bordeaux, Inserm, Bordeaux Population Health Research Center, CHU Bordeaux, Bordeaux, France., Shah N; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, UK.; Department of Pharmacy, COMSATS Institute of Information Technology, Abbottabad, Pakistan., Surendran P; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Thériault S; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.; Institut universitaire de cardiologie et de pneumologie de Québec-Université Laval, Quebec City, Quebec, Canada., Verweij N; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA.; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, the Netherlands., Willems SM; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Zhao JH; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Amouyel P; University of Lille, Inserm, Centre Hosp. Univ. Lille, Institut Pasteur de Lille, UMR1167 - RID-AGE - Risk factors and molecular determinants of aging-related diseases, Epidemiology and Public Health Department, Lille, France., Connell J; University of Dundee, Ninewells Hospital & Medical School, Dundee, UK., de Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Doney ASF; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, UK., Farrall M; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Menni C; Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK., Morris AD; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Noordam R; Department of Internal Medicine, Section Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., Paré G; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada., Poulter NR; Imperial Clinical Trials Unit, London, UK., Shields DC; School of Medicine, University College Dublin, Dublin, Ireland., Stanton A; Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland., Thom S; International Centre for Circulatory Health, Imperial College London, London, UK., Abecasis G; Center for Statistical Genetics, Department of Biostatistics, SPH II, Washington Heights, Ann Arbor, MI, USA., Amin N; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., Arking DE; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Ayers KL; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.; Sema4, a Mount Sinai venture, Stamford, CT, USA., Barbieri CM; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Batini C; Department of Health Sciences, University of Leicester, Leicester, UK., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Blake T; Department of Health Sciences, University of Leicester, Leicester, UK., Bochud M; Institute of Social and Preventive Medicine, University Hospital of Lausanne, Lausanne, Switzerland., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Boerwinkle E; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston and Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Boomsma DI; Department of Biological Psychology, Vrije Universiteit Amsterdam, EMGO+ Institute, VU University Medical Center, Amsterdam, the Netherlands., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Braund PS; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Brumat M; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Campbell A; Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK., Campbell H; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK., Chakravarti A; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Department of Cardiology, Ealing Hospital, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK., Chauhan G; Centre for Brain Research, Indian Institute of Science, Bangalore, India., Ciullo M; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Napoli, Italy.; IRCCS Neuromed, Pozzilli, Isernia, Italy., Cocca M; Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy., Collins F; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD, USA., Cordell HJ; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK., Davies G; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., de Borst MH; Department of Internal Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., de Geus EJ; Department of Biological Psychology, Vrije Universiteit Amsterdam, EMGO+ Institute, VU University Medical Center, Amsterdam, the Netherlands., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Deelen J; Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Del Greco M F; Institute for Biomedicine, Eurac Research, Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck, Germany., Demirkale CY; Mathematical and Statistical Computing Laboratory, Office of Intramural Research, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA., Dörr M; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Ehret GB; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Cardiology, Department of Medicine, Geneva University Hospital, Geneva, Switzerland., Elosua R; CIBERCV & Cardiovascular Epidemiology and Genetics, IMIM, Barcelona, Spain.; Faculty of Medicine, Universitat de Vic-Central de Catalunya, Vic, Spain., Enroth S; Department of Immunology, Genetics and Pathology, Uppsala Universitet, Science for Life Laboratory, Uppsala, Sweden., Erzurumluoglu AM; Department of Health Sciences, University of Leicester, Leicester, UK., Ferreira T; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Big Data Institute, Li Ka Shing Center for Health for Health Information and Discovery, Oxford University, Oxford, UK., Frånberg M; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Centre for Molecular Medicine, L8:03, Karolinska Universitetsjukhuset, Solna, Sweden.; Department of Numerical Analysis and Computer Science, Stockholm University, Stockholm, Sweden., Franco OH; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., Gandin I; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Gasparini P; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy., Giedraitis V; Department of Public Health and Caring Sciences, Geriatrics, Uppsala, Sweden., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany., Girotto G; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy., Goel A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Gow AJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, School of Social Sciences, Heriot-Watt University, Edinburgh, UK., Gudnason V; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Gyllensten U; Department of Immunology, Genetics and Pathology, Uppsala Universitet, Science for Life Laboratory, Uppsala, Sweden., Hamsten A; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Centre for Molecular Medicine, L8:03, Karolinska Universitetsjukhuset, Solna, Sweden., Harris TB; Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD, USA., Harris SE; Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Hartman CA; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Havulinna AS; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Hicks AA; Institute for Biomedicine, Eurac Research, Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck, Germany., Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria.; Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria., Hofman A; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Hottenga JJ; Department of Biological Psychology, Vrije Universiteit Amsterdam, EMGO+ Institute, VU University Medical Center, Amsterdam, the Netherlands., Huffman JE; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK.; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; The Population Science Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Hwang SJ; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; The Population Science Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., James A; Department of Pulmonary Physiology and Sleep, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, Western Australia, Australia.; School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia., Jansen R; Department of Psychiatry, VU University Medical Center, Amsterdam Neuroscience, Amsterdam, the Netherlands., Jarvelin MR; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Center For Life-course Health Research, University of Oulu, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Oulu, Finland., Joehanes R; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; Hebrew SeniorLife, Harvard Medical School, Boston, MA, USA., Johansson Å; Department of Immunology, Genetics and Pathology, Uppsala Universitet, Science for Life Laboratory, Uppsala, Sweden., Johnson AD; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Joshi PK; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK., Jousilahti P; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Jula A; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.; Department of Clinical Physiology, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Kathiresan S; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA., Keavney BD; Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Division of Medicine, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Khaw KT; Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge, UK., Knekt P; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Knight J; Data Science Institute and Lancaster Medical School, Lancaster, UK., Kolcic I; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia., Kooner JS; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Koskinen S; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Kristiansson K; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Kutalik Z; Institute of Social and Preventive Medicine, University Hospital of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Laan M; Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia., Larson M; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA., Launer LJ; Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD, USA., Lehne B; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Liewald DCM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Lin L; Cardiology, Department of Medicine, Geneva University Hospital, Geneva, Switzerland., Lind L; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Big Data Institute, Li Ka Shing Center for Health for Health Information and Discovery, Oxford University, Oxford, UK.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Liu Y; Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Loos RJF; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Mindich Child Health Development Institute, The Icahn School of Medicine at Mount Sinai, New York, NY, USA., Lopez LM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin, Ireland.; University College Dublin, UCD Conway Institute, Centre for Proteome Research, UCD, Belfield, Dublin, Ireland., Lu Y; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Mamasoula C; Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK., Marrugat J; CIBERCV & Cardiovascular Epidemiology and Genetics, IMIM, Barcelona, Spain., Marten J; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Milaneschi Y; Department of Psychiatry, Amsterdam Public Health and Amsterdam Neuroscience, VU University Medical Center/GGZ inGeest, Amsterdam, the Netherlands., Morgan A; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Biostatistics, University of Liverpool, Liverpool, UK., Morrison AC; Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Munson PJ; Mathematical and Statistical Computing Laboratory, Office of Intramural Research, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA., Nalls MA; Data Tecnica International, Glen Echo, MD, USA.; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA., Nandakumar P; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Niiranen T; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland.; Department of Medicine, Turku University Hospital and University of Turku, Turku, Finland., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Nutile T; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Napoli, Italy., Oldehinkel AJ; Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Oostra BA; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., O'Reilly PF; SGDP Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Org E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Padmanabhan S; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK.; British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Palmas W; Department of Medicine, Columbia University Medical Center, New York, NY, USA., Palotie A; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Analytic and Translational Genetics Unit, Department of Medicine, Department of Neurology and Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; The Stanley Center for Psychiatric Research and Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Pattie A; Department of Psychology, University of Edinburgh, Edinburgh, UK., Penninx BWJH; Department of Psychiatry, Amsterdam Public Health and Amsterdam Neuroscience, VU University Medical Center/GGZ inGeest, Amsterdam, the Netherlands., Perola M; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; University of Tartu, Tartu, Estonia., Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.; German Center for Cardiovascular Disease Research (DZHK), partner site Munich, Neuherberg, Germany., Polasek O; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.; Psychiatric Hospital 'Sveti Ivan', Zagreb, Croatia., Pramstaller PP; Institute for Biomedicine, Eurac Research, Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck, Germany.; Department of Neurology, General Central Hospital, Bolzano, Italy.; Department of Neurology, University of Lübeck, Lübeck, Germany., Nguyen QT; Mathematical and Statistical Computing Laboratory, Office of Intramural Research, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Ren M; Fujian Key Laboratory of Geriatrics, Department of Geriatric Medicine, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China., Rettig R; Institute of Physiology, University Medicine Greifswald, Karlsburg, Germany., Rice K; Department of Biostatistics, University of Washington, Seattle, WA, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Ried JS; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Riese H; Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Ripatti S; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Robino A; Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy., Rose LM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK., Ruggiero D; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Napoli, Italy.; IRCCS Neuromed, Pozzilli, Isernia, Italy., Saba Y; Gottfried Schatz Research Center for Cell Signaling, Metabolism & Aging, Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria., Sala CF; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Salomaa V; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Sarin AP; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Schmidt R; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria., Schmidt H; Gottfried Schatz Research Center for Cell Signaling, Metabolism & Aging, Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria., Shrine N; Department of Health Sciences, University of Leicester, Leicester, UK., Siscovick D; The New York Academy of Medicine, New York, NY, USA., Smith AV; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Sõber S; Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia., Sorice R; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Napoli, Italy., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK., Stott DJ; Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, UK., Strachan DP; Population Health Research Institute, St George's, University of London, London, UK., Strawbridge RJ; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Centre for Molecular Medicine, L8:03, Karolinska Universitetsjukhuset, Solna, Sweden., Sundström J; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Swertz MA; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Taylor KD; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Teumer A; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Tobin MD; Department of Health Sciences, University of Leicester, Leicester, UK., Tomaszewski M; Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Division of Medicine, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Toniolo D; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Traglia M; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., Tuomilehto J; Dasman Diabetes Institute, Dasman, Kuwait.; Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Saudi Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Tzourio C; Univ. Bordeaux, Inserm, Bordeaux Population Health Research Center, CHU Bordeaux, Bordeaux, France., Uitterlinden AG; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus MC, Rotterdam, the Netherlands., Vaez A; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., van Duijn CM; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., Vergnaud AC; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Verwoert GC; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., Vitart V; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Völker U; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Vollenweider P; Department of Internal Medicine, University Hospital, CHUV, Lausanne, Switzerland., Vuckovic D; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.; Experimental Genetics Division, Sidra Medical and Research Center, Doha, Qatar., Watkins H; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Wild SH; Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK., Willemsen G; Department of Biological Psychology, Vrije Universiteit Amsterdam, EMGO+ Institute, VU University Medical Center, Amsterdam, the Netherlands., Wilson JF; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK.; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK., Wright AF; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Yao J; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Zemunik T; Department of Biology, Faculty of Medicine, University of Split, Split, Croatia., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK., Attia JR; Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New Lambton Heights, New South Wales, Australia., Butterworth AS; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; The National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Conen D; Division of Cardiology, University Hospital, Basel, Switzerland.; Division of Cardiology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada., Cucca F; Institute of Genetic and Biomedical Research, National Research Council (CNR), Monserrato, Cagliari, Italy.; Department of Biomedical Sciences, University of Sassari, Sassari, Italy., Danesh J; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; The National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK., Hayward C; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Howson JMM; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Lakatta EG; Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Melander O; Department Clinical Sciences, Malmö, Lund University, Malmö, Sweden., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands., Palmer CNA; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, UK., Risch L; Labormedizinisches Zentrum Dr. Risch, Schaan, Liechtenstein.; Private University of the Principality of Liechtenstein, Triesen, Liechtenstein.; University Institute of Clinical Chemistry, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Scott RA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Scott RJ; Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New Lambton Heights, New South Wales, Australia., Sever P; National Heart and Lung Institute, Imperial College London, London, UK., Spector TD; Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK., van der Harst P; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Zeggini E; Wellcome Trust Sanger Institute, Hinxton, UK., Levy D; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Munroe PB; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK., Newton-Cheh C; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA., Brown MJ; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia., Hung AM; Tennessee Valley Healthcare System (Nashville VA) & Vanderbilt University, Nashville, TN, USA., O'Donnell CJ; VA Boston Healthcare, Section of Cardiology and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Edwards TL; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Psaty BM; Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology and Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA., Tzoulaki I; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK., Barnes MR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK., Wain LV; Department of Health Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Elliott P; Department of Epidemiology and Biostatistics, Imperial College London, London, UK. p.elliott@imperial.ac.uk.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK. p.elliott@imperial.ac.uk.; National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare NHS Trust and Imperial College London, London, UK. p.elliott@imperial.ac.uk.; UK Dementia Research Institute (UK DRI) at Imperial College London, London, UK. p.elliott@imperial.ac.uk.; Health Data Research-UK London substantive site, London, UK. p.elliott@imperial.ac.uk., Caulfield MJ; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. m.j.caulfield@qmul.ac.uk.; National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK. m.j.caulfield@qmul.ac.uk.
Publikováno v:
Nature genetics [Nat Genet] 2018 Dec; Vol. 50 (12), pp. 1755.
Autor:
Gibson R; Nutrition and Dietetic Research Group, Faculty of Medicine, Imperial College, University of London, London, W12 0NN, UK. Rachel.gibson13@imperial.ac.uk., Eriksen R; Nutrition and Dietetic Research Group, Faculty of Medicine, Imperial College, University of London, London, W12 0NN, UK., Singh D; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College, London, W2 1PG, UK., Vergnaud AC; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College, London, W2 1PG, UK., Heard A; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College, London, W2 1PG, UK., Chan Q; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College, London, W2 1PG, UK., Elliott P; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College, London, W2 1PG, UK., Frost G; Nutrition and Dietetic Research Group, Faculty of Medicine, Imperial College, University of London, London, W12 0NN, UK.
Publikováno v:
European journal of nutrition [Eur J Nutr] 2018 Dec; Vol. 57 (8), pp. 2913-2926. Date of Electronic Publication: 2017 Nov 02.
Autor:
Vergnaud AC; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, United Kingdom., Aresu M; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, United Kingdom., Kongsgård HW; Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Norway., McRobie D; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, United Kingdom., Singh D; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, United Kingdom., Spear J; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, United Kingdom., Heard A; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, United Kingdom., Gao H; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, United Kingdom., Carpenter JR; Medical Statistics Unit, London School of Hygiene and Tropical Medicine London, WC1E 7HT, United Kingdom., Elliott P; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, United Kingdom; Imperial College London NIHR Biomedical Research Centre, London, United Kingdom; Health Data Research UK-London, London, United Kingdom. Electronic address: p.elliott@imperial.ac.uk.
Publikováno v:
Environmental research [Environ Res] 2018 Nov; Vol. 167, pp. 169-174. Date of Electronic Publication: 2018 Jul 09.
Autor:
Evangelou E; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Warren HR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK., Mosen-Ansorena D; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Mifsud B; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Pazoki R; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Gao H; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK., Ntritsos G; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Dimou N; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Cabrera CP; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK., Karaman I; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Ng FL; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Evangelou M; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Mathematics, Imperial College London, London, UK., Witkowska K; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Tzanis E; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Hellwege JN; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Giri A; Vanderbilt Genetics Institute, Vanderbilt Epidemiology Center, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center; Tennessee Valley Health Systems VA, Nashville, TN, USA., Velez Edwards DR; Vanderbilt Genetics Institute, Vanderbilt Epidemiology Center, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center; Tennessee Valley Health Systems VA, Nashville, TN, USA., Sun YV; Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA, USA.; Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, USA., Cho K; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA.; Division of Aging, Department of Medicine, Brigham and Women's Hospital; Department of Medicine, Harvard Medical School, Boston, MA, USA., Gaziano JM; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA.; Division of Aging, Department of Medicine, Brigham and Women's Hospital; Department of Medicine, Harvard Medical School, Boston, MA, USA., Wilson PWF; Atlanta VAMC and Emory Clinical Cardiovascular Research Institute, Atlanta, GA, USA., Tsao PS; VA Palo Alto Health Care System, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA., Kovesdy CP; Nephrology Section, Memphis VA Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA., Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Mägi R; Estonian Genome Center, University of Tartu, Tartu, Estonia., Milani L; Estonian Genome Center, University of Tartu, Tartu, Estonia., Almgren P; Department Clinical Sciences, Malmö, Lund University, Malmö, Sweden., Boutin T; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Debette S; Department of Neurology, Bordeaux University Hospital, Bordeaux, France.; Univ. Bordeaux, Inserm, Bordeaux Population Health Research Center, CHU Bordeaux, Bordeaux, France., Ding J; Laboratory of Genetics and Genomics, NIA/NIH, Baltimore, MD, USA., Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA., Holliday EG; Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New Lambton Heights, New South Wales, Australia., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Lin WY; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Mangino M; Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK.; NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust, London, UK., Oldmeadow C; Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New Lambton Heights, New South Wales, Australia., Prins BP; Wellcome Trust Sanger Institute, Hinxton, UK., Qian Y; Laboratory of Genetics and Genomics, NIA/NIH, Baltimore, MD, USA., Sargurupremraj M; Univ. Bordeaux, Inserm, Bordeaux Population Health Research Center, CHU Bordeaux, Bordeaux, France., Shah N; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, UK.; Department of Pharmacy, COMSATS Institute of Information Technology, Abbottabad, Pakistan., Surendran P; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Thériault S; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.; Institut universitaire de cardiologie et de pneumologie de Québec-Université Laval, Quebec City, Quebec, Canada., Verweij N; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA.; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, the Netherlands., Willems SM; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Zhao JH; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Amouyel P; University of Lille, Inserm, Centre Hosp. Univ. Lille, Institut Pasteur de Lille, UMR1167 - RID-AGE - Risk factors and molecular determinants of aging-related diseases, Epidemiology and Public Health Department, Lille, France., Connell J; University of Dundee, Ninewells Hospital & Medical School, Dundee, UK., de Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Doney ASF; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, UK., Farrall M; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Menni C; Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK., Morris AD; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Noordam R; Department of Internal Medicine, Section Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., Paré G; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada., Poulter NR; Imperial Clinical Trials Unit, London, UK., Shields DC; School of Medicine, University College Dublin, Dublin, Ireland., Stanton A; Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland., Thom S; International Centre for Circulatory Health, Imperial College London, London, UK., Abecasis G; Center for Statistical Genetics, Department of Biostatistics, SPH II, Washington Heights, Ann Arbor, MI, USA., Amin N; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., Arking DE; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Ayers KL; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.; Sema4, a Mount Sinai venture, Stamford, CT, USA., Barbieri CM; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Batini C; Department of Health Sciences, University of Leicester, Leicester, UK., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Blake T; Department of Health Sciences, University of Leicester, Leicester, UK., Bochud M; Institute of Social and Preventive Medicine, University Hospital of Lausanne, Lausanne, Switzerland., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Boerwinkle E; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston and Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Boomsma DI; Department of Biological Psychology, Vrije Universiteit Amsterdam, EMGO+ Institute, VU University Medical Center, Amsterdam, the Netherlands., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Braund PS; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Brumat M; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Campbell A; Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK., Campbell H; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK., Chakravarti A; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Department of Cardiology, Ealing Hospital, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK., Chauhan G; Centre for Brain Research, Indian Institute of Science, Bangalore, India., Ciullo M; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Napoli, Italy.; IRCCS Neuromed, Pozzilli, Isernia, Italy., Cocca M; Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy., Collins F; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD, USA., Cordell HJ; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK., Davies G; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., de Borst MH; Department of Internal Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., de Geus EJ; Department of Biological Psychology, Vrije Universiteit Amsterdam, EMGO+ Institute, VU University Medical Center, Amsterdam, the Netherlands., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Deelen J; Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Del Greco M F; Institute for Biomedicine, Eurac Research, Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck, Germany., Demirkale CY; Mathematical and Statistical Computing Laboratory, Office of Intramural Research, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA., Dörr M; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Ehret GB; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Cardiology, Department of Medicine, Geneva University Hospital, Geneva, Switzerland., Elosua R; CIBERCV & Cardiovascular Epidemiology and Genetics, IMIM, Barcelona, Spain.; Faculty of Medicine, Universitat de Vic-Central de Catalunya, Vic, Spain., Enroth S; Department of Immunology, Genetics and Pathology, Uppsala Universitet, Science for Life Laboratory, Uppsala, Sweden., Erzurumluoglu AM; Department of Health Sciences, University of Leicester, Leicester, UK., Ferreira T; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Big Data Institute, Li Ka Shing Center for Health for Health Information and Discovery, Oxford University, Oxford, UK., Frånberg M; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Centre for Molecular Medicine, L8:03, Karolinska Universitetsjukhuset, Solna, Sweden.; Department of Numerical Analysis and Computer Science, Stockholm University, Stockholm, Sweden., Franco OH; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., Gandin I; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Gasparini P; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy., Giedraitis V; Department of Public Health and Caring Sciences, Geriatrics, Uppsala, Sweden., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany., Girotto G; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy., Goel A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Gow AJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, School of Social Sciences, Heriot-Watt University, Edinburgh, UK., Gudnason V; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Gyllensten U; Department of Immunology, Genetics and Pathology, Uppsala Universitet, Science for Life Laboratory, Uppsala, Sweden., Hamsten A; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Centre for Molecular Medicine, L8:03, Karolinska Universitetsjukhuset, Solna, Sweden., Harris TB; Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD, USA., Harris SE; Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Hartman CA; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Havulinna AS; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Hicks AA; Institute for Biomedicine, Eurac Research, Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck, Germany., Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria.; Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria., Hofman A; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Hottenga JJ; Department of Biological Psychology, Vrije Universiteit Amsterdam, EMGO+ Institute, VU University Medical Center, Amsterdam, the Netherlands., Huffman JE; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK.; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; The Population Science Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Hwang SJ; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; The Population Science Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., James A; Department of Pulmonary Physiology and Sleep, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, Western Australia, Australia.; School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia., Jansen R; Department of Psychiatry, VU University Medical Center, Amsterdam Neuroscience, Amsterdam, the Netherlands., Jarvelin MR; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Center For Life-course Health Research, University of Oulu, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Oulu, Finland., Joehanes R; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; Hebrew SeniorLife, Harvard Medical School, Boston, MA, USA., Johansson Å; Department of Immunology, Genetics and Pathology, Uppsala Universitet, Science for Life Laboratory, Uppsala, Sweden., Johnson AD; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Joshi PK; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK., Jousilahti P; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Jula A; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.; Department of Clinical Physiology, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Kathiresan S; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA., Keavney BD; Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Division of Medicine, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Khaw KT; Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge, UK., Knekt P; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Knight J; Data Science Institute and Lancaster Medical School, Lancaster, UK., Kolcic I; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia., Kooner JS; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Koskinen S; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Kristiansson K; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Kutalik Z; Institute of Social and Preventive Medicine, University Hospital of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Laan M; Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia., Larson M; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA., Launer LJ; Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD, USA., Lehne B; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Liewald DCM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Lin L; Cardiology, Department of Medicine, Geneva University Hospital, Geneva, Switzerland., Lind L; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Big Data Institute, Li Ka Shing Center for Health for Health Information and Discovery, Oxford University, Oxford, UK.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Liu Y; Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Loos RJF; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Mindich Child Health Development Institute, The Icahn School of Medicine at Mount Sinai, New York, NY, USA., Lopez LM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin, Ireland.; University College Dublin, UCD Conway Institute, Centre for Proteome Research, UCD, Belfield, Dublin, Ireland., Lu Y; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Mamasoula C; Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK., Marrugat J; CIBERCV & Cardiovascular Epidemiology and Genetics, IMIM, Barcelona, Spain., Marten J; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Milaneschi Y; Department of Psychiatry, Amsterdam Public Health and Amsterdam Neuroscience, VU University Medical Center/GGZ inGeest, Amsterdam, the Netherlands., Morgan A; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Biostatistics, University of Liverpool, Liverpool, UK., Morrison AC; Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Munson PJ; Mathematical and Statistical Computing Laboratory, Office of Intramural Research, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA., Nalls MA; Data Tecnica International, Glen Echo, MD, USA.; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA., Nandakumar P; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Niiranen T; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland.; Department of Medicine, Turku University Hospital and University of Turku, Turku, Finland., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Nutile T; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Napoli, Italy., Oldehinkel AJ; Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Oostra BA; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., O'Reilly PF; SGDP Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Org E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Padmanabhan S; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK.; British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Palmas W; Department of Medicine, Columbia University Medical Center, New York, NY, USA., Palotie A; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Analytic and Translational Genetics Unit, Department of Medicine, Department of Neurology and Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; The Stanley Center for Psychiatric Research and Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Pattie A; Department of Psychology, University of Edinburgh, Edinburgh, UK., Penninx BWJH; Department of Psychiatry, Amsterdam Public Health and Amsterdam Neuroscience, VU University Medical Center/GGZ inGeest, Amsterdam, the Netherlands., Perola M; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; University of Tartu, Tartu, Estonia., Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.; German Center for Cardiovascular Disease Research (DZHK), partner site Munich, Neuherberg, Germany., Polasek O; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.; Psychiatric Hospital 'Sveti Ivan', Zagreb, Croatia., Pramstaller PP; Institute for Biomedicine, Eurac Research, Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck, Germany.; Department of Neurology, General Central Hospital, Bolzano, Italy.; Department of Neurology, University of Lübeck, Lübeck, Germany., Nguyen QT; Mathematical and Statistical Computing Laboratory, Office of Intramural Research, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Ren M; Fujian Key Laboratory of Geriatrics, Department of Geriatric Medicine, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China., Rettig R; Institute of Physiology, University Medicine Greifswald, Karlsburg, Germany., Rice K; Department of Biostatistics, University of Washington, Seattle, WA, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Ried JS; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Riese H; Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Ripatti S; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Robino A; Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy., Rose LM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK., Ruggiero D; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Napoli, Italy.; IRCCS Neuromed, Pozzilli, Isernia, Italy., Saba Y; Gottfried Schatz Research Center for Cell Signaling, Metabolism & Aging, Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria., Sala CF; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Salomaa V; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Sarin AP; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Schmidt R; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria., Schmidt H; Gottfried Schatz Research Center for Cell Signaling, Metabolism & Aging, Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria., Shrine N; Department of Health Sciences, University of Leicester, Leicester, UK., Siscovick D; The New York Academy of Medicine, New York, NY, USA., Smith AV; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Sõber S; Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia., Sorice R; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Napoli, Italy., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK., Stott DJ; Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, UK., Strachan DP; Population Health Research Institute, St George's, University of London, London, UK., Strawbridge RJ; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Centre for Molecular Medicine, L8:03, Karolinska Universitetsjukhuset, Solna, Sweden., Sundström J; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Swertz MA; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Taylor KD; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Teumer A; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Tobin MD; Department of Health Sciences, University of Leicester, Leicester, UK., Tomaszewski M; Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Division of Medicine, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Toniolo D; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Traglia M; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., Tuomilehto J; Dasman Diabetes Institute, Dasman, Kuwait.; Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Saudi Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Tzourio C; Univ. 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MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK.; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK., Wright AF; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Yao J; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Zemunik T; Department of Biology, Faculty of Medicine, University of Split, Split, Croatia., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK., Attia JR; Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New Lambton Heights, New South Wales, Australia., Butterworth AS; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; The National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Conen D; Division of Cardiology, University Hospital, Basel, Switzerland.; Division of Cardiology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada., Cucca F; Institute of Genetic and Biomedical Research, National Research Council (CNR), Monserrato, Cagliari, Italy.; Department of Biomedical Sciences, University of Sassari, Sassari, Italy., Danesh J; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; The National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK., Hayward C; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Howson JMM; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Lakatta EG; Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Melander O; Department Clinical Sciences, Malmö, Lund University, Malmö, Sweden., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands., Palmer CNA; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, UK., Risch L; Labormedizinisches Zentrum Dr. Risch, Schaan, Liechtenstein.; Private University of the Principality of Liechtenstein, Triesen, Liechtenstein.; University Institute of Clinical Chemistry, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Scott RA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Scott RJ; Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New Lambton Heights, New South Wales, Australia., Sever P; National Heart and Lung Institute, Imperial College London, London, UK., Spector TD; Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK., van der Harst P; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Zeggini E; Wellcome Trust Sanger Institute, Hinxton, UK., Levy D; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; 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Tennessee Valley Healthcare System (Nashville VA) & Vanderbilt University, Nashville, TN, USA., O'Donnell CJ; VA Boston Healthcare, Section of Cardiology and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Edwards TL; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Psaty BM; Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology and Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA., Tzoulaki I; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK., Barnes MR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK., Wain LV; Department of Health Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Elliott P; Department of Epidemiology and Biostatistics, Imperial College London, London, UK. p.elliott@imperial.ac.uk.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK. p.elliott@imperial.ac.uk.; National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare NHS Trust and Imperial College London, London, UK. p.elliott@imperial.ac.uk.; UK Dementia Research Institute (UK DRI) at Imperial College London, London, UK. p.elliott@imperial.ac.uk.; Health Data Research-UK London substantive site, London, UK. p.elliott@imperial.ac.uk., Caulfield MJ; 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Publikováno v:
Nature genetics [Nat Genet] 2018 Oct; Vol. 50 (10), pp. 1412-1425. Date of Electronic Publication: 2018 Sep 17.