Zobrazeno 41 - 50
of 217
pro vyhledávání: '"Valmik Bhargava"'
Autor:
Mei Hua Gao, David Murray, Alan S. Maisel, Nancy D. Dalton, H. Kirk Hammond, Denise Barnard, Clyde W. Yancy, William F. Penny, Amit N. Patel, Timothy D. Henry, Robert S. Ross, Ranya Sweis, Sanjiv M. Narayan, Jay H. Traverse, Martin Lee, Valmik Bhargava, Daniel G. Blanchard, N. Chin Lai, Eric Adler, Matthew W. Watkins
Publikováno v:
Hammond, HK; Penny, WF; Traverse, JH; Henry, TD; Watkins, M; Yancy, C; et al.(2016). Intracoronary Gene Transfer of Adenylyl Cyclase 6 in Patients With Heart Failure A Randomized Clinical Trial. JAMA CARDIOLOGY, 1(2), 163-171. doi: 10.1001/jamacardio.2016.0008. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/26r0w2kk
JAMA cardiology, vol 1, iss 2
JAMA cardiology, vol 1, iss 2
ImportanceGene transfer has rarely been tested in randomized clinical trials.ObjectiveTo evaluate the safety and efficacy of intracoronary delivery of adenovirus 5 encoding adenylyl cyclase 6 (Ad5.hAC6) in heart failure.Design, setting, and participa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b267ef385efbd6ebf86a0c3943f1fe
http://www.escholarship.org/uc/item/26r0w2kk
http://www.escholarship.org/uc/item/26r0w2kk
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 8, p e0161536 (2016)
PLoS ONE, Vol 11, Iss 8, p e0161536 (2016)
Methods commonly used clinically to assess cardiac function in patients with heart failure include ejection fraction (EF), exercise treadmill testing (ETT), and symptom evaluation. Although these approaches are useful in evaluating patients with hear
Autor:
Adam Kassan, Hemal H. Patel, M. Raj Rajasekaran, Johnny Fu, Valmik Bhargava, Alice E. Zemljic-Harpf, Karnam S. Murthy
Publikováno v:
Journal of Urology. 195
INTRODUCTION AND OBJECTIVES: Pathophysiology of increased severity of erectile dysfunction (ED) in diabetic men and their poor response to phosphodiesterase 5 (PDE5) inhibitors are unclear. A defective vascular endothelium and consequent impairment i
Autor:
M. Raj Rajasekaran, Jan M. Schilling, Jay Parikh, Tung-Chin Hsieh, Hemal H. Patel, Dimosthenis Giamouridis, Valmik Bhargava
Publikováno v:
Journal of Urology. 195
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 302:G542-G547
A subthreshold pharyngeal stimulus induces lower esophageal sphincter (LES) relaxation and inhibits progression of ongoing peristaltic contraction in the esophagus. Recent studies show that longitudinal muscle contraction of the esophagus may play a
Publikováno v:
Gastroenterology. 140:442-449
Surgical fundoplication is an effective treatment for gastroesophageal reflux disease. One of the proposed mechanisms for its antireflux action is that it reduces lower esophageal sphincter (LES) relaxation. We investigated whether fundoplication wor
Publikováno v:
Gastroenterology. 139:102-111
Background & Aims Achalasia esophagus is characterized by loss of peristalsis and incomplete esophagogastric junction (EGJ) relaxation. We studied mechanisms of esophageal emptying in patients with achalasia using simultaneous high-resolution manomet
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 298:G927-G933
Multipeaked waves (MPW) in the distal esophagus occur frequently in patients with esophageal spastic motor disorders and diabetes mellitus and are thought to represent repetitive esophageal contractions. We aimed to investigate whether the relative m
Mechanism of stretch-activated excitatory and inhibitory responses in the lower esophageal sphincter
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 297:G397-G405
We recently found that an orally directed stretch of the esophagus activates a neurally mediated relaxation of the lower esophageal sphincter (LES). Goals of our study were to characterize the neural mechanisms responsible for axial and transverse st
Publikováno v:
Alimentary Pharmacology & Therapeutics. 29:863-870
Summary Background Proton pump inhibitor (PPI) therapy is known to suppress gastric acid secretion. Thus PPI therapy may decrease gastric volume and gastric contents available for gastro-oesophageal reflux by decreasing acid secretion. Aim To determi