Zobrazeno 11 - 20
of 627
pro vyhledávání: '"Ulf-Håkan Stenman"'
Autor:
Anni Sjöblom, Ulf-Håkan Stenman, Jaana Hagström, Lauri Jouhi, Caj Haglund, Stina Syrjänen, Petri Mattila, Antti Mäkitie, Timo Carpén
Publikováno v:
Cancers, Vol 13, Iss 11, p 2811 (2021)
Background: We studied the role of tumor-associated trypsin inhibitor (TATI) in serum and in tumor tissues among human papillomavirus (HPV)-positive and HPV-negative OPSCC patients. Materials and methods: The study cohort included 90 OPSCC patients t
Externí odkaz:
https://doaj.org/article/e46609a628c642a6833479d145d4eb18
Autor:
Sawan Kumar Jha, Khushbu Rauniyar, Ewa Chronowska, Kenny Mattonet, Eunice Wairimu Maina, Hannu Koistinen, Ulf-Håkan Stenman, Kari Alitalo, Michael Jeltsch
Publikováno v:
eLife, Vol 8 (2019)
Vascular endothelial growth factor-C (VEGF-C) acts primarily on endothelial cells, but also on non-vascular targets, for example in the CNS and immune system. Here we describe a novel, unique VEGF-C form in the human reproductive system produced via
Externí odkaz:
https://doaj.org/article/e097b88514914dc3a4bc098e00f63dc8
Autor:
Neill Booth, Pekka Rissanen, Teuvo L J Tammela, Paula Kujala, Ulf-Håkan Stenman, Kimmo Taari, Kirsi Talala, Anssi Auvinen
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224479 (2019)
In contrast to earlier studies which have used modelling to perform cost-effectiveness analysis, this study links data from a randomised controlled trial with register data from nationwide registries to reveal new evidence on costs, effectiveness, an
Externí odkaz:
https://doaj.org/article/697d2d455661426cba791644d5dd2781
Autor:
Reetta Peltonen, Pia Österlund, Marko Lempinen, Arno Nordin, Ulf-Håkan Stenman, Helena Isoniemi
Publikováno v:
Tumor Biology, Vol 40 (2018)
Liver metastases of colorectal cancer can be operated with a curative intent in selected cases. However, more than half of the patients have a recurrence. The aim of this study was to evaluate the prognostic and predictive value of carcinoembryonic a
Externí odkaz:
https://doaj.org/article/1c2a1493b4314e6c95e69a5fc3eb02fc
Autor:
Eleanor L Watts, Paul N Appleby, Demetrius Albanes, Amanda Black, June M Chan, Chu Chen, Piera M Cirillo, Barbara A Cohn, Michael B Cook, Jenny L Donovan, Luigi Ferrucci, Cedric F Garland, Graham G Giles, Phyllis J Goodman, Laurel A Habel, Christopher A Haiman, Jeff M P Holly, Robert N Hoover, Rudolf Kaaks, Paul Knekt, Laurence N Kolonel, Tatsuhiko Kubo, Loïc Le Marchand, Tapio Luostarinen, Robert J MacInnis, Hanna O Mäenpää, Satu Männistö, E Jeffrey Metter, Roger L Milne, Abraham M Y Nomura, Steven E Oliver, J Kellogg Parsons, Petra H Peeters, Elizabeth A Platz, Elio Riboli, Fulvio Ricceri, Sabina Rinaldi, Harri Rissanen, Norie Sawada, Catherine A Schaefer, Jeannette M Schenk, Frank Z Stanczyk, Meir Stampfer, Pär Stattin, Ulf-Håkan Stenman, Anne Tjønneland, Antonia Trichopoulou, Ian M Thompson, Shoichiro Tsugane, Lars Vatten, Alice S Whittemore, Regina G Ziegler, Naomi E Allen, Timothy J Key, Ruth C Travis
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0187741 (2017)
IntroductionSex hormones have been implicated in the etiology of a number of diseases. To better understand disease etiology and the mechanisms of disease-risk factor associations, this analysis aimed to investigate the associations of anthropometric
Externí odkaz:
https://doaj.org/article/220b20dddc614ed5b5cb7519e7c7fb1c
Autor:
Aino Salmiheimo, Harri Mustonen, Ulf-Håkan Stenman, Pauli Puolakkainen, Esko Kemppainen, Hanna Seppänen, Caj Haglund
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163064 (2016)
BACKGROUND:Estimation of the prognosis of resectable pancreatic ductal adenocarcinoma (PDAC) currently relies on tumour-related factors such as resection margins and on lymph-node ratio (LNR) both inconveniently available only postoperatively. Our ai
Externí odkaz:
https://doaj.org/article/af5668138b964e29bd9dcdcd963450d2
Autor:
Lin Feng, Susanna Lintula, Tho Huu Ho, Maria Anastasina, Annukka Paju, Caj Haglund, Ulf-Håkan Stenman, Kristina Hotakainen, Arto Orpana, Denis Kainov, Jakob Stenman
Publikováno v:
BioTechniques, Vol 52, Iss 4, Pp 263-270 (2012)
Primer-independent cDNA synthesis during reverse transcription hinders quantitative analysis of bidirectional mRNA synthesis in eukaryotes as well as in cells infected with RNA viruses. We report a simple RT-PCR-based assay for strand-specific gene-e
Externí odkaz:
https://doaj.org/article/5498c73ad25046a7b37a4fa82d7317d2
Autor:
Johanna M Mattsson, Suvi Ravela, Can Hekim, Magnus Jonsson, Johan Malm, Ale Närvänen, Ulf-Håkan Stenman, Hannu Koistinen
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107819 (2014)
Prostate-specific antigen (PSA or kallikrein-related peptidase-3, KLK3) exerts chymotrypsin-like proteolytic activity. The main biological function of PSA is the liquefaction of the clot formed after ejaculation by cleavage of semenogelins I and II i
Externí odkaz:
https://doaj.org/article/1f1c120f20594723b2832bec8b0fcda8
Autor:
Selja Koskensalo, Johanna Louhimo, Jaana Hagström, Mikael Lundin, Ulf-Håkan Stenman, Caj Haglund
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76906 (2013)
BACKGROUND: Epidermal growth factor receptor (EGFR) activation plays a role in colorectal cancer (CRC) carcinogenesis, and anti-EGFR drugs are used in treatment of advanced CRC. One of the EGFR ligands is tumor-associated trypsinogen inhibitor TATI,
Externí odkaz:
https://doaj.org/article/437439efb3d54d3ab8489cccd5f126b5
Autor:
Hannu Koistinen, Ruusu‐Maaria Kovanen, Morley D. Hollenberg, Antoine Dufour, Evette S. Radisky, Ulf‐Håkan Stenman, Jyotsna Batra, Judith Clements, John D. Hooper, Eleftherios Diamandis, Oliver Schilling, Antti Rannikko, Tuomas Mirtti
Publikováno v:
IUBMB Life. 75:493-513
Since the proposition of the pro-invasive activity of proteolytic enzymes over 70 years ago, several roles for proteases in cancer progression have been established. About half of the 473 active human proteases are expressed in the prostate and many