Zobrazeno 41 - 50
of 141
pro vyhledávání: '"Toru Sakura"'
Publikováno v:
Leukemia & Lymphoma. 59:253-255
The translocation t(8;16)(p11;p13), which results in fusion of the MOZ/MYST3/KAT6A gene (8p11) and CBP/CREBBP gene (16p13), is characterized by unique morphologic and clinical findings in acute mye...
Autor:
Hiroshi Handa, Toru Sakura, Hiroaki Shimizu, Satoru Takada, Takayuki Saitoh, Akihiko Yokohama, Takuma Ishizaki, Nahoko Hatsumi
Publikováno v:
Blood. 134:5690-5690
Background: Extramedullary (EM) relapses were sometimes observed in acute leukemia patients both after chemotherapy and allo-SCT. Our recent study described that the rate of EM relapses after allo-SCT was significantly higher when comparing with that
Autor:
Yoshinori Tanaka, Naoyuki Uchida, Heiwa Kanamori, Noriko Doki, Shigeki Ohtake, Toru Sakura, Kazuhiro Ikegame, Shuichi Ota, Fumihiko Hayakawa, Yasushi Miyazaki, Shinichi Kako, Shingo Kurahashi, Shuichi Mizuta, Itaru Matsumura, Yoshiko Atsuta, Satoshi Nishiwaki, Tohru Murayama, Tatsuo Ichinohe, Noriko Usui, Takahiro Fukuda, Hitoshi Kiyoi, Kiyotoshi Imai, Junji Tanaka
Publikováno v:
Blood. 134:4589-4589
[Background] We previously demonstrated that allogeneic hematopoietic stem cell transplantation (HSCT) in the first complete remission (CR1) was recommended for adult patients wih Philadelphia chromosome (Ph)-negative acute lymphoblastic leukemia (AL
Autor:
Yoshiyuki Ogawa, Kana Soma, Hiroaki Shimizu, Eiko Yamane, Takayuki Saitoh, Satoru Takada, Masanobu Sunaga, Nao Hashimoto, Norifumi Tsukamoto, Takuma Ishizaki, Rei Ishihara, Yuki Murakami, Toru Sakura, Akihiko Yokohama, Yuta Asao, Hiroshi Handa, Maaya Awata, Gotoh Nanami, Tetsuhiro Kasamatsu
Publikováno v:
Blood. 134:1431-1431
Background: Acute myeloid leukemia (AML) is a hematological malignancy characterized by the autonomous growth of immature myeloid cells with impaired differentiation and maturation. Cytokines are low-molecular-weight proteins that play a basic and fu
Autor:
Kensuke Usuki, Toru Sakura, Masahito Kaneko, Tomoki Naoe, Satoshi Morita, Yukio Kobayashi, Shunsuke Yamada, Toshihiro Miyamoto, Shigeru Takeshita, Hiroatsu Iida, Erkut Bahceci, Mikiko Kusano, Shuichi Miyawaki
Publikováno v:
Cancer Science
Gilteritinib, a novel, highly specific, potent fms-like tyrosine kinase 3/AXL inhibitor, demonstrated antileukemic activity in patients with relapsed/refractory (R/R) acute myeloid leukemia (AML). In this open-label phase 1 study (NCT02181660), Japan
Autor:
Toru Sakura, Raine Tatara, Kenji Motohashi, Noriko Doki, Jun Taguchi, Shingo Yano, Takayuki Saitoh, Kensuke Usuki, Sumiko Kobayashi, Emiko Sakaida, Shinichi Kako, Katsuhiro Shono, S. Okamoto, Satoru Takahashi, Nobutaka Kawai, M Onizuka, E Fuji, Shin Fujisawa, Naoto Tomita, Heiwa Kanamori, Reiko Watanabe, Takehiko Mori, Nobuyuki Aotsuka
Publikováno v:
Bone Marrow Transplantation. 50:1476-1479
Effect of the order of TBI and cyclophosphamide administration on the outcome of allogeneic hematopoietic stem cell transplantation
Autor:
Hiroaki Shimizu, Toru Sakura, Tetsuhiro Kasamatsu, Norifumi Tsukamoto, Yusuke Minato, Hiroshi Handa, Akihiko Yokohama, Takayuki Saitoh, Hirokazu Murakami
Publikováno v:
European Journal of Haematology. 96:245-251
Polymorphisms of the interleukin-10 (IL-10) gene, which alter the production of IL-10, have been implicated in many cancers. We investigated the association between gene polymorphisms of the promoter region of IL-10 (-1082 G/A, IL-10-819 C/T, and -59
Autor:
Noriko Doki, Shinichiro Okamoto, Shinichi Kako, Takehiko Mori, Shuichi Miyawaki, Takayuki Saitoh, Yoshinobu Kanda, Hiroaki Shimizu, Toru Sakura, Shinichiro Machida, Heiwa Kanamori
Publikováno v:
European Journal of Haematology. 95:455-460
Adult patients with mixed phenotype acute leukemia (MPAL) have a poor prognosis, and the therapeutic role of allogeneic stem cell transplantation (allo-SCT) for MPAL remains to be elucidated. Thus, we retrospectively assessed the efficacy of allo-SCT
Autor:
Kayoko Matsumoto, Nobuyuki Aotsuka, Satoru Takahashi, M Tanaka, Takayoshi Tachibana, Heiwa Kanamori, Ayumi Numata, Masahiro Onoda, Kazuteru Ohashi, Shinichiro Okamoto, H. Sakamaki, Kensuke Usuki, Toru Sakura, Chiaki Nakaseko, Sinichiro Machida, Yoshinobu Kanda, Takeshi Kobayashi, Jun Taguchi, Shingo Yano, J. Kato, Etsuko Yamazaki, Reiko Watanabe, Shin Fujisawa, Jun Ooi, T. Saito
Publikováno v:
Bone Marrow Transplantation. 50:727-733
This prospective study aimed to investigate the influence of pretransplant serum ferritin levels on the outcomes of allogeneic hematopoietic SCT (HSCT). In total, 190 patients with acute leukemia or myelodysplastic syndrome were consecutively enrolle
Autor:
Tetsuya Eto, Kazuteru Ohashi, Shuichi Taniguchi, Toru Sakura, Kiyotoshi Imai, Masatsugu Tanaka, Koichi Miyamura, Takahiro Fukuda, Tokiko Nagamura-Inoue, Yoshiko Atsuta, Hiroatsu Ago, Naoyuki Uchida, Seitaro Terakura, Shinichiro Mori, Shinichiro Okamoto
Publikováno v:
Biology of Blood and Marrow Transplantation. 21(3):517-525
We retrospectively compared the transplantation outcomes for patients 50 years or older who received umbilical cord blood transplantation (UCBT) with those who received unrelated bone marrow transplantation (UBMT) for hematologic malignancies. A tota