Zobrazeno 91 - 100
of 141
pro vyhledávání: '"Toru Sakura"'
Autor:
Shigeki Ito, Naoya Nakamura, Michiaki Koike, Hideto Tamura, Hiroshi Handa, Norifumi Tsukamoto, Hirotaka Nakahashi, Kohtaro Toyama, Morio Matsumoto, Toru Sakura, Sakae Tanosaki, Makoto Sasaki, Masamitsu Karasawa, Akihiko Yokohama, Asaka Onodera, Atsushi Isoda, Masanori Iwashina, Yutaka Tsukune, Morio Sawamura, Masaru Kojima, Hirokazu Murakami, Keiichi Moriya, Akio Saito, Kayoko Murayama
Publikováno v:
Blood. 126:5028-5028
Background: Analysis of prognostic factors and clinical trials of novel agents for Waldenstrӧm macroglobulinemia (WM) are ongoing in Western countries, but few studies of WM have been performed in Japan. As a step toward future investigations, we re
Effectiveness of High-Dose MTX Therapy for Adult Ph-Negative ALL By Randomized Trial: JALSG ALL202-O
Autor:
Yukio Kobayashi, Hitoshi Kiyoi, Kiyotoshi Imai, Toshiaki Yujiri, Shigeki Ohtake, Shin Fujisawa, Toru Sakura, Keitaro Matsuo, Yasushi Miyazaki, Isamu Sugiura, Tohru Murayama, Noriko Usui, Fumihiko Hayakawa, Kazunori Ohnishi, Tomoki Naoe
Publikováno v:
Blood. 126:79-79
The effectiveness of high-dose (HD) methotrexate (MTX) therapy was confirmed in pediatric acute lymphoblastic leukemia (ALL) by randomized control studies. Recently, as protocols for pediatric ALL are used for young adult ALL, HD-MTX therapy is used
Autor:
Toru Sakura, Shuichi Miyawaki, Shigeru Takeshita, Erkut Bahceci, Masahito Kaneko, Shunsuke Yamada, Tomoki Naoe, Satoshi Morita, Yukio Kobayashi, Kensuke Usuki, Toshihiro Miyamoto, Hiroatsu Iida
Publikováno v:
Blood. 126:1320-1320
Background: FMS-like tyrosine kinase 3 (FLT3) mutations in patients with acute myeloid leukemia (AML) are strongly associated with poor prognosis and leukocytosis. Approximately 15-35% of AML patients have internal tandem duplication (ITD) of the jux
Autor:
Shingo Yano, Kazuteru Ohashi, Moritaka Goto, Shin Fujisawa, Makoto Onizuka, Kensuke Usuki, Chiaki Nakaseko, Nobuyuki Aotsuka, Heiwa Kanamori, Reiko Watanabe, Takayuki Saitoh, Yasuhito Nannya, Hiroaki Shimizu, Yoshinobu Kanda, Jun Taguchi, Naoto Tomita, Hisashi Wakita, Satoshi Takahashi, Toru Sakura, Shinichiro Okamoto
Publikováno v:
Blood. 126:2024-2024
Background: Cytogenetic abnormalities at diagnosis are recognized as a potent prognostic factor for acute leukemia patients. Among acute myeloid leukemia patients, the prognostic implications of cytogenetic abnormalities have been established for tho
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 15:S13
Autor:
Takayuki Saitoh, Toru Sakura, Takumi Hoshino, Hiroaki Shimizu, Nahoko Hatsumi, Akinori Yuzuriha, Yoshihisa Nojima, Satoru Takada, Hiroko Koya, Tomohito Nagaki
Publikováno v:
International journal of hematology. 94(5)
Post-transplant lymphoproliferative disorder (PTLD) is a fatal complication of allogeneic hematopoietic stem cell transplantation (HSCT) that is caused by reactivation of Epstein–Barr virus (EBV). A successful approach, monitoring EBV-DNA load in p
Autor:
Noriko Usui, Yuichi Yahagi, Shigeki Ohtake, Chiaki Nakaseko, Akihiro Takeshita, Kazunori Ohnishi, Tomoki Naoe, Nobuaki Dobashi, Kazuyuki Shigeno, Hiroyuki Fujita, Chikako Ohwada, Hitoshi Kiyoi, Yukio Kobayashi, Shuichi Miyawaki, Toru Sakura, Yasushi Miyazaki
Publikováno v:
Cancer science. 102(7)
In order to investigate better molecular-target therapy for acute myeloid leukemia (AML), we conducted a phase I trial of a combination of gemtuzumab ozogamicin (GO) with conventional chemotherapy. Between January 2007 and December 2009, a total of 1
Autor:
Takahiro Yamauchi, Takashi Watanabe, Tomomitsu Hotta, Toru Sakura, Naokuni Uike, Kiyoshi Ando, Kensei Tobinai, Hiroya Asou, Toshiya Yokozawa, Kosuke Tsuboi, Rika Kihara, Shin Fujisawa, Shuichi Miyawaki
Publikováno v:
Leukemia research. 35(10)
Barasertib (AZD1152) is a highly potent and selective Aurora B kinase inhibitor. The safety, efficacy and pharmacokinetic (PK) profile of barasertib were investigated in Japanese patients with advanced acute myeloid leukemia. Barasertib (50-1200mg) w
Autor:
Jun Tsuchiya, Kenji Kashiwabara, Toru Sakura, Hiroko Shiozaki, Teruo Kitani, Kunihiko Yashiro, Hisami Hirabayashi, Shuichi Miyawaki, Hirokazu Murakami, Takashi Machii
Publikováno v:
Internal Medicine. 32:472-475
A 64-year-old male suffered from splenomegaly without lymphadenopathy. His WBC count on admission was 6.1×l09/l with 55% abnormal lymphocytes. No monoclonal gammopathy was detected. Abnormal cells shown in films usually had relatively abundant cytop
Autor:
Satoshi Takahashi, Satoshi Morita, Jin Takeuchi, Yasushi Miyazaki, Hisashi Sakamaki, Shinichi Kako, Itsuro Jinnai, Taiichi Kyo, Toru Sakura, K Iwato, Tomoki Naoe, M Onizuka, Tetsuya Fukuda, Hiroyasu Ogawa, Heiwa Kanamori, Ritsuro Suzuki, Yoshinobu Kanda, Kazunori Ohnishi, S Miyawaki, Yoshiko Atsuta
Publikováno v:
Leukemia. 25(2)
Clinical studies using genetic randomization cannot accurately answer whether adult patients with Philadelphia chromosome-negative acute lymphoblastic leukemia (ALL) who have a human leukocyte antigen (HLA)-matched sibling should undergo allogeneic h