Zobrazeno 51 - 60
of 177
pro vyhledávání: '"Timo K. van den Berg"'
Autor:
Anton T.J. Tool, Taco W. Kuijpers, Martin de Boer, Haike Reznik Wolf, Baruch Wolach, Ronit Gavrieli, Yifaat Bar-Yosef, Anat Bar-Ziv, Maya Dushnitzki, Shlomo Lipitz, Tal Elkan Miller, Dirk Roos, Timo K. van den Berg, Doron M. Behar, Elon Pras, Karin van Leeuwen
Publikováno v:
Journal of Medical Genetics, 55(3), 166-172. BMJ Publishing Group
De Boer, M, Gavrieli, R, van Leeuwen, K, Wolf, H R, Dushnitzki, M, Bar-Yosef, Y, Bar-Ziv, A, Behar, D, Lipitz, S, Miller, T E, Tool, A T J, Kuijpers, T W, van den Berg, T K, Wolach, B, Roos, D & Pras, E 2018, ' A false-carrier state for the c.579G >A mutation in the NCF1 gene in Ashkenazi Jews ', Journal of Medical Genetics, vol. 55, no. 3, pp. 166-172 . https://doi.org/10.1136/jmedgenet-2017-105022
Journal of medical genetics, 55(3), 166-172. BMJ Publishing Group
De Boer, M, Gavrieli, R, van Leeuwen, K, Wolf, H R, Dushnitzki, M, Bar-Yosef, Y, Bar-Ziv, A, Behar, D, Lipitz, S, Miller, T E, Tool, A T J, Kuijpers, T W, van den Berg, T K, Wolach, B, Roos, D & Pras, E 2018, ' A false-carrier state for the c.579G >A mutation in the NCF1 gene in Ashkenazi Jews ', Journal of Medical Genetics, vol. 55, no. 3, pp. 166-172 . https://doi.org/10.1136/jmedgenet-2017-105022
Journal of medical genetics, 55(3), 166-172. BMJ Publishing Group
BackgroundMutations in the NCF1 gene that encodes p47phox, a subunit of the NADPH oxidase complex, cause chronic granulomatous disease (CGD). In Kavkazi Jews, a c.579G>A (p.Trp193Ter) mutation in NCF1 is frequently found, leading to CGD. The same mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29529a00c6b82902f2cea3a0135d1fb
https://research.vumc.nl/en/publications/254c1a88-9257-4511-a7f9-32f230db0ab5
https://research.vumc.nl/en/publications/254c1a88-9257-4511-a7f9-32f230db0ab5
Autor:
Timo K. van den Berg, Judy Geissler, Taco W. Kuijpers, Patricia Gonzalez, Xi Wen Zhao, Sietse Q. Nagelkerke, Joris van der Heijden, Michel van Houdt, Hanke L. Matlung, Martin de Boer, Paul Verkuijlen, Dieke J van Rees, Louise W. Treffers
Publikováno v:
Treffers, L W, Zhao, X W, van der Heijden, J, Nagelkerke, S Q, van Rees, D J, Gonzalez, P, Geissler, J, Verkuijlen, P, van Houdt, M, de Boer, M, Kuijpers, T W, van den Berg, T K & Matlung, H L 2018, ' Genetic variation of human neutrophil Fcγ receptors and SIRPα in antibody-dependent cellular cytotoxicity towards cancer cells ', European Journal of Immunology, vol. 48, no. 2, pp. 344-354 . https://doi.org/10.1002/eji.201747215
European Journal of Immunology, 48(2), 344-354. Wiley-VCH Verlag
European journal of immunology, 48(2), 344-354. Wiley-VCH Verlag
European Journal of Immunology, 48(2), 344-354. Wiley-VCH Verlag
European journal of immunology, 48(2), 344-354. Wiley-VCH Verlag
The efficacy of cancer therapeutic antibodies varies considerably among patients. Anticancer antibodies act through different mechanisms, including antibody-dependent cellular cytotoxicity (ADCC) triggered via Fc gamma receptors (Fc gamma R). This ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4d039b7716657adbd8fbbe407227bf
https://research.vumc.nl/en/publications/907cf272-4dd8-4fd6-9f8b-d657babe3e0d
https://research.vumc.nl/en/publications/907cf272-4dd8-4fd6-9f8b-d657babe3e0d
Autor:
Thomas Valerius, Timo K. van den Berg
Publikováno v:
Nature reviews. Clinical oncology, 16, 275-276. Nature Publishing Group
The first-in-human study of anti-CD47 antibodies blocking CD47–SIRPα interactions in combination with rituximab in patients with non-Hodgkin lymphoma shows encouraging clinical responses accompanied with mild levels of toxicity. Inhibition of the
Autor:
C. Michel Zwaan, Jacqueline Cloos, Eveline S. J. M. de Bont, Erik R Abels, Marry M. van den Heuvel-Eibrink, Gertjan J.L. Kaspers, Josta Parigger, Zinia J. Kwidama, Mahban Irandoust, Timo K. van den Berg, Ewart de Bruijn, Mercan Akyuz, Edwin Cuppen, Valerie de Haas, Dirk Reinhardt, Yehuda G. Assaraf, Nika Heijmans, David G. J. Cucchi, Richard Broekhuizen
Publikováno v:
Journal of Molecular and Clinical Medicine, 1(1):DOI: 10.31083/j.jmcm.2018.01.001, 1-6
Cloos, J, Cucchi, DGJ, Irandoust, M, Assaraf, Y G, Kaspers, GJL, Akyuz, M, Broekhuizen, A J F, Heijmans, N, Abels, E R, Parigger, J, Kwidama, ZJ, van den Berg, T K, de Haas, V, Reinhardt, D, M van den Heuvel-Eibrink, M, De Bont, E S J M, Zwaan, C M, Cuppen, E & de Bruijn, E 2017, ' Phosphatase Sequencing of Pediatric Acute Myeloid Leukemia Reveals a Novel Mutation in the Phosphatase Gene PTPN4 ', Journal of Molecular and Clinical Medicine, vol. 1, no. 1, DOI: 10.31083/j.jmcm.2018.01.001, pp. 1-6 . < http://www.imrpress.org/upload/pdf/logo_15390491601127967179.pdf >
Cloos, J, Cucchi, DGJ, Irandoust, M, Assaraf, Y G, Kaspers, GJL, Akyuz, M, Broekhuizen, A J F, Heijmans, N, Abels, E R, Parigger, J, Kwidama, ZJ, van den Berg, T K, de Haas, V, Reinhardt, D, M van den Heuvel-Eibrink, M, De Bont, E S J M, Zwaan, C M, Cuppen, E & de Bruijn, E 2017, ' Phosphatase Sequencing of Pediatric Acute Myeloid Leukemia Reveals a Novel Mutation in the Phosphatase Gene PTPN4 ', Journal of Molecular and Clinical Medicine, vol. 1, no. 1, DOI: 10.31083/j.jmcm.2018.01.001, pp. 1-6 . < http://www.imrpress.org/upload/pdf/logo_15390491601127967179.pdf >
It has been well established that dysregulated activation of kinases is essential for the development of acute myeloid leukemia(AML). In contrast, little is known about the role of their dephosphorylation counterparts, the tyrosine phosphatases. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf1bf3cefe65c288bab8d5d0e06b797
https://research.vumc.nl/en/publications/94d80fce-ae4e-49ae-ad72-ee74a717f3d7
https://research.vumc.nl/en/publications/94d80fce-ae4e-49ae-ad72-ee74a717f3d7
Autor:
Anne H van der Spek, Timo K. van den Berg, Anton T.J. Tool, Olga V. Surovtseva, Saskia Aan, Korcan Demir, A S Paul van Trotsenburg, Anita Boelen, Annemarie van de Geer, Anja L M van Gucht, Eric Fliers
Publikováno v:
Endocrine Connections, 6(8), 731-740. BioScientifica Ltd.
Endocrine Connections
Endocrine Connections, 6(8), 731-740. Bioscientifica Ltd
van Der Spek, A H, Surovtseva, O V, Aan, S, Tool, A T J, van de Geer, A, Demir, K, van Gucht, A L M, van Trotsenburg, A S P, van den Berg, T K, Fliers, E & Boelen, A 2017, ' Increased circulating interleukin-8 in patients with resistance to thyroid hormone receptor α ', Endocrine Connections, vol. 6, no. 8, pp. 731-740 . https://doi.org/10.1530/EC-17-0213
Endocrine Connections, Vol 6, Iss 8, Pp 731-740 (2017)
Endocrine connections, 6(8), 731-740. BioScientifica Ltd.
Endocrine Connections
Endocrine Connections, 6(8), 731-740. Bioscientifica Ltd
van Der Spek, A H, Surovtseva, O V, Aan, S, Tool, A T J, van de Geer, A, Demir, K, van Gucht, A L M, van Trotsenburg, A S P, van den Berg, T K, Fliers, E & Boelen, A 2017, ' Increased circulating interleukin-8 in patients with resistance to thyroid hormone receptor α ', Endocrine Connections, vol. 6, no. 8, pp. 731-740 . https://doi.org/10.1530/EC-17-0213
Endocrine Connections, Vol 6, Iss 8, Pp 731-740 (2017)
Endocrine connections, 6(8), 731-740. BioScientifica Ltd.
Innate immune cells have recently been identified as novel thyroid hormone (TH) target cells in which intracellular TH levels appear to play an important functional role. The possible involvement of TH receptor alpha (TRα), which is the predominant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df0d6bf03e294e8feeab388d80e29206
https://research.vumc.nl/en/publications/6c3ae5ae-afc6-4621-97fa-dc7510375ff2
https://research.vumc.nl/en/publications/6c3ae5ae-afc6-4621-97fa-dc7510375ff2
Autor:
Timo K. van den Berg, Katka Szilagyi, Georg Kraal, Marion J.J. Gijbels, Sigrid E.M. Heinsbroek, Saskia van der Velden, Menno P.J. de Winther
Publikováno v:
Szilagyi, K, Gijbels, M J J, van der Velden, S, Heinsbroek, S E M, Kraal, G, de Winther, M P J & van den Berg, T K 2015, ' Dectin-1 deficiency does not affect atherosclerosis development in mice ', Atherosclerosis, vol. 239, no. 2, pp. 318-321 . https://doi.org/10.1016/j.atherosclerosis.2015.02.005
Atherosclerosis, 239(2), 318-321. Elsevier Ireland Ltd
Atherosclerosis, 239(2), 318-321. Elsevier Ireland Ltd
Objective Recent data suggest the involvement of dectin-1 in atherosclerosis through regulation of local reactive oxygen species production. The aim of the current study was to assess the effect of dectin-1 deficiency on atherosclerotic plaque develo
Autor:
Erikjan Rijkers, Laura Gutierrez, Hans Janssen, Harmen J.G. van de Werken, Marjolein Meinders, Rutger W W Brouwer, Guntram Suske, Timo K. van den Berg, Sjaak Philipsen, Wilfred F. J. van IJcken, Mark Hoogenboezem, Imme Krüger, Jeroen Demmers, Divine I. Kulu
Publikováno v:
Meinders, M, Kulu, D I, van de Werken, H J G, Hoogenboezem, M, Janssen, H, Brouwer, R W W, van Ijcken, W F J, Rijkers, E-J, Demmers, J A A, Krüger, I, van den Berg, T K, Suske, G, Gutiérrez, L & Philipsen, S 2015, ' Sp1/Sp3 transcription factors regulate hallmarks of megakaryocyte maturation and platelet formation and function ', Blood, vol. 125, no. 12, pp. 1957-67 . https://doi.org/10.1182/blood-2014-08-593343
Blood, 125(12), 1957-67. American Society of Hematology
Blood, 125(12), 1957-1967. American Society of Hematology
Blood, 125(12), 1957-67. American Society of Hematology
Blood, 125(12), 1957-1967. American Society of Hematology
Sp1 and Sp3 belong to the specificity proteins (Sp)/Krüppel-like transcription factor family. They are closely related, ubiquitously expressed, and recognize G-rich DNA motifs. They are thought to regulate generic processes such as cell-cycle and gr
Autor:
Saskia van der Velden, Menno P.J. de Winther, Jan Van den Bossche, Hanke L. Matlung, Timo K. van den Berg, Annette E. Neele, Marten A. Hoeksema, Marieke C.S. Boshuizen, Pieter Goossens, Brendon P. Scicluna
Publikováno v:
Journal of immunology (Baltimore, Md., 194(8), 3909-3916. American Association of Immunologists
Macrophages form a heterogeneous population of immune cells, which is critical for both the initiation and resolution of inflammation. They can be skewed to a proinflammatory subtype by the Th1 cytokine IFN-γ and further activated with TLR triggers,
Autor:
Carolien A. M. Koeleman, Wim J E van Esch, Marcella de Boer, Taco W. Kuijpers, Manfred Wuhrer, Suzanne N. Lissenberg-Thunnissen, Rosina Plomp, Hanke L. Matlung, Juk Yee Mok, Mieke C. Brouwer, Theo Rispens, Remco Visser, Gestur Vidarsson, Louise W. Treffers, Arthur E. H. Bentlage, Timo K. van den Berg, Diana Wouters, Gillian Dekkers
Publikováno v:
Frontiers in Immunology, 8
Frontiers in immunology, 8. Frontiers Media S.A.
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology
Frontiers in immunology, 8. Frontiers Media S.A.
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology
Glycosylation of the immunoglobulin G (IgG)-Fc tail is required for binding to Fc-gamma receptors (FcγRs) and complement-component C1q. A variety of IgG1-glycoforms is detected in human sera. Several groups have found global or antigen-specific skew
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e66a2d915ab552de4c5a62fdb22a029
http://hdl.handle.net/1887/114803
http://hdl.handle.net/1887/114803
Autor:
Sanne M. Meinderts, Takashi Matozaki, Robin van Bruggen, Boukje M. Beuger, Taco W. Kuijpers, Thomas R. L. Klei, Johanna Johansson, Masja de Haas, Per-Arne Oldenborg, Elise J. Huisman, Timo K. van den Berg
Publikováno v:
Blood, 1(14), 875-886. American Society of Hematology
Blood advances, 1(14), 875-886. American Society of Hematology
Meinderts, S M, Oldenborg, P-A, Beuger, B M, Klei, T R L, Johansson, J, Kuijpers, T W, Matozaki, T, Huisman, E J, de Haas, M, van den Berg, T K & van Bruggen, R 2017, ' Human and murine splenic neutrophils are potent phagocytes of IgG-opsonized red blood cells ', Blood, vol. 1, no. 14, pp. 875-886 . https://doi.org/10.1182/bloodadvances.2017004671
Blood advances, 1(14), 875-886. American Society of Hematology
Meinderts, S M, Oldenborg, P-A, Beuger, B M, Klei, T R L, Johansson, J, Kuijpers, T W, Matozaki, T, Huisman, E J, de Haas, M, van den Berg, T K & van Bruggen, R 2017, ' Human and murine splenic neutrophils are potent phagocytes of IgG-opsonized red blood cells ', Blood, vol. 1, no. 14, pp. 875-886 . https://doi.org/10.1182/bloodadvances.2017004671
Red blood cell (RBC) clearance is known to occur primarily in the spleen, and is presumed to be executed by red pulp macrophages. Erythrophagocytosis in the spleen takes place as part of the homeostatic turnover of RBCs to remove old RBCs. It can be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::979588ef8ec747b113cd50e7d9f6f87d
https://research.vumc.nl/en/publications/4b1bfcee-a2c2-490f-b5c2-38ca1e64ecf3
https://research.vumc.nl/en/publications/4b1bfcee-a2c2-490f-b5c2-38ca1e64ecf3