Zobrazeno 31 - 40
of 177
pro vyhledávání: '"Timo K. van den Berg"'
Autor:
Arno van Heijst, Judy Geissler, Emile van den Akker, Michel van Houdt, Wouter Koole, Koen J. van Aerde, Han J.M.P. Verhagen, Ivo van der Bijl, Cathelijn E.M. Aarts, Gerald Jaspers, Christine W. Bruggeman, Anton T.J. Tool, Evelien G. G. Sprenkeler, Thatjana Gardeitchik, Floris P. J. van Alphen, Iris C. Kreft, Martin de Boer, Hans Janssen, Taco W. Kuijpers, Stefanie S. V. Henriet, Kian D. Liem, Paul Verkuijlen, Timo K. van den Berg, Simon Tol, Robin van Bruggen
Publikováno v:
Blood, 135(24), 2171-2181. American Society of Hematology
Blood, 135, 24, pp. 2171-2181
Blood, 135, 2171-2181
Blood
Blood, 135, 24, pp. 2171-2181
Blood, 135, 2171-2181
Blood
Megakaryoblastic leukemia 1 (MKL1) promotes the regulation of essential cell processes, including actin cytoskeletal dynamics, by coactivating serum response factor. Recently, the first human with MKL1 deficiency, leading to a novel primary immunodef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b809e6d92354a647f689ade8ce4f44
https://pure.amc.nl/en/publications/mkl1-deficiency-results-in-a-severe-neutrophil-motility-defect-due-to-impaired-actin-polymerization(8e622be7-3e65-412f-b3c2-5eedcabc6963).html
https://pure.amc.nl/en/publications/mkl1-deficiency-results-in-a-severe-neutrophil-motility-defect-due-to-impaired-actin-polymerization(8e622be7-3e65-412f-b3c2-5eedcabc6963).html
Autor:
Vishal Salunkhe, Sjaak Philipsen, Rutger W W Brouwer, Timo K. van den Berg, Nynke Gillemans, Jeroen Demmers, Lianne van de Laar, Erikjan Rijkers, Wilfred F. J. van IJcken, Noemí Caballero-Sánchez, Iris M. De Cuyper, Pieter De Bleser, Maaike R. Scheenstra, Laura Gutierrez, Andrea Acebes-Huerta, Patricia Martínez-Botía, Benjamin Nota, Andrea M. Woltman, Taco W. Kuijpers
Publikováno v:
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Journal of leukocyte biology, 110(4), 735-751. FASEB
Journal of Leukocyte Biology, 1-17. John Wiley & Sons Inc.
STARTPAGE=1;ENDPAGE=17;ISSN=0741-5400;TITLE=Journal of Leukocyte Biology
instname
Journal of leukocyte biology, 110(4), 735-751. FASEB
Journal of Leukocyte Biology, 1-17. John Wiley & Sons Inc.
STARTPAGE=1;ENDPAGE=17;ISSN=0741-5400;TITLE=Journal of Leukocyte Biology
Dendritic cells (DCs) are key immune modulators and are able to mount immune responses or tolerance. DC differentiation and activation imply a plethora of molecular and cellular responses, including transcriptional changes. PU.1 is a highly expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948526b0e9c69ecf828402662f0b66b5
http://hdl.handle.net/10651/57182
http://hdl.handle.net/10651/57182
Autor:
Katka Franke, Saravanan Y. Pillai, Mark Hoogenboezem, Marion J. J. Gijbels, Hanke L. Matlung, Judy Geissler, Hugo Olsman, Chantal Pottgens, Patrick J. van Gorp, Maria Ozsvar-Kozma, Yasuyuki Saito, Takashi Matozaki, Taco W. Kuijpers, Rudi W. Hendriks, Georg Kraal, Christoph J. Binder, Menno P. J. de Winther, Timo K. van den Berg
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, 11:570963. Frontiers Media S.A.
Frontiers in Immunology, Vol 11 (2020)
Frontiers in immunology, 11:570963. Frontiers Media S.A.
Frontiers in Immunology, 11:570963. Frontiers Media S.A.
Frontiers in Immunology, Vol 11 (2020)
Frontiers in immunology, 11:570963. Frontiers Media S.A.
The inhibitory immunoreceptor SIRP alpha is expressed on myeloid and neuronal cells and interacts with the broadly expressed CD47. CD47-SIRP alpha interactions form an innate immune checkpoint and its targeting has shown promising results in cancer p
Autor:
Timo K. van den Berg, Sanne M. Meinderts, Robin van Bruggen, Judy Geissler, Sadaf Pakdaman, Michael W.T. Tanck, Taco W. Kuijpers, J.L. Kerkhoffs, Christine W. Bruggeman, Karin Fijnvandraat, Anita W. Rijneveld, Bart J. Biemond, Anoosha Habibi, Joep W. R. Sins, Sietse Q. Nagelkerke
Publikováno v:
Meinderts, S M, Sins, J W R, Fijnvandraat, K, Nagelkerke, S Q, Geissler, J, Tanck, M W, Bruggeman, C, Biemond, B J, Rijneveld, A W, Kerkhoffs, J L H, Pakdaman, S, Habibi, A, Van Bruggen, R, Kuijpers, T W, Pirenne, F & Van Den Berg, T K 2017, ' Nonclassical FCGR2C haplotype is associated with protection from red blood cell alloimmunization in sickle cell disease ', Blood, vol. 130, no. 19, pp. 2121-2130 . https://doi.org/10.1182/blood-2017-05-784876
Blood, 130(19), 2121-2130. American Society of Hematology
Blood, 130(19), 2121-2130. American Society of Hematology
Red blood cell (RBC) transfusions are of vital importance in patients with sickle cell disease (SCD). However, a major complication of transfusion therapy is alloimmunization. The low-affinity Fcg receptors, expressed on immune cells, are important r
Autor:
Martin de Boer, Floris P. J. van Alphen, Martijn van der Kuip, Taco W. Kuijpers, Hans Janssen, Suzanne W.J. Terheggen, Karin van Leeuwen, Timo K. van den Berg, Judy Geissler, Alexander B. Meijer, Dirk Roos, Esther de Vries
Publikováno v:
Human Mutation. 38:1402-1411
Hermansky-Pudlak syndrome type 2 (HPS2) is a syndrome caused by mutations in the beta-3A subunit of the adaptor protein (AP)-3 complex (AP3B1 gene). We describe five unreported cases with four novel mutations, one of which caused aberrant pre-mRNA sp
Publikováno v:
Matlung, H L, Szilagyi, K, Barclay, N A & van den Berg, T K 2017, ' The CD47-SIRPα signaling axis as an innate immune checkpoint in cancer ', Immunological Reviews, vol. 276, no. 1, pp. 145-164 . https://doi.org/10.1111/imr.12527
Immune checkpoint inhibitors, including those targeting CTLA-4/B7 and the PD-1/PD-L1 inhibitory pathways, are now available for clinical use in cancer patients, with other interesting checkpoint inhibitors being currently in development. Most of thes
Autor:
Ida H. Hiemstra, Machiel H Janssen, John L. van Hamme, Taco W. Kuijpers, Timo K. van den Berg
Publikováno v:
Transfusion. 57:674-684
BACKGROUND Granulocyte transfusion (GTX) is a potential approach to correcting neutropenia and relieving the increased risk of infection in patients who are refractory to antibiotics. To mobilize enough granulocytes for transfusion, healthy donors ar
Autor:
Bas van Steensel, Katka Franke, Melania Balzarolo, Edith M. Janssen, Timo K. van den Berg, Anja J. de Jong, Sander Engels, Monika C. Wolkers
Nucleic acid sensing through pattern recognition receptors is critical for immune recognition of microbial infections. Microbial DNA is frequently methylated at the N6 position of adenines (m6A), a modification that is rare in mammalian host DNA. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6074a38afb74a54b5bdfbe1729ed0939
Autor:
Koen A. Marijt, Timo K. van den Berg, Arianne M. Brandsma, Matthijs Raaben, Raquel Gomez-Eerland, Ton N. Schumacher, Noor A. M. Bakker, Jacques Neefjes, Astrid Fauster, Thijn R. Brummelkamp, Mireille Toebes, Simone van der Schot, Jeanette H. W. Leusen, Joost H. van den Berg, Martijn Verdoes, Katka Franke, Hanke L. Matlung, Ferenc A. Scheeren, J. H. Marco Jansen, Meike Emma Willemijn Logtenberg, John B. A. G. Haanen
Publikováno v:
Nature medicine
Nature Medicine, 25, 4, pp. 612-619
Nature medicine, 25(4), 612-619. Nature Publishing Group
Nature Medicine, 25(4), 612
Nature Medicine
Nature Medicine, 25, 612-619
Nature Medicine, 25, 4, pp. 612-619
Nature medicine, 25(4), 612-619. Nature Publishing Group
Nature Medicine, 25(4), 612
Nature Medicine
Nature Medicine, 25, 612-619
Cancer cells are able to evade immune surveillance through the expression of inhibitory ligands that bind their cognate receptors on immune effector cells. Expression of Programmed Death-Ligand 1 (PD-L1) in tumor micro-environments is a major immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7424239d9777176a6df9b7f382570737
https://doi.org/10.1038/s41591-019-0356-z
https://doi.org/10.1038/s41591-019-0356-z
Autor:
Steffen Kahle, Jan M. Prins, Jeanette H. W. Leusen, Taco W. Kuijpers, Louise W. Treffers, Michel van Houdt, Paul Verkuijlen, Toine ten Broeke, Hanke L. Matlung, Karin Schornagel, Thies Rösner, Timo K. van den Berg, J. H. Marco Jansen, Katka Franke, Thomas Valerius
Publikováno v:
Cancer Immunology Research, 8(1), 120. American Association for Cancer Research Inc.
Cancer immunology research, 8(1), 120-130. American Association for Cancer Research Inc.
Cancer immunology research, 8(1), 120-130. American Association for Cancer Research Inc.
Therapeutic monoclonal antibodies (mAb), directed toward either tumor antigens or inhibitory checkpoints on immune cells, are effective in cancer therapy. Increasing evidence suggests that the therapeutic efficacy of these tumor antigen–targeting m